Global to push GA events into
skip to main content

Title: System and method for dose verification and gamma ray imaging in ion beam therapy

This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.
Issue Date:
OSTI Identifier:
The Regents of the University of California (Oakland, CA) LBNL
Patent Number(s):
Application Number:
Contract Number:
Resource Relation:
Patent File Date: 2015 Oct 19
Research Org:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org:
Country of Publication:
United States

Works referenced in this record:

Development of array-type prompt gamma measurement system for in vivo range verification in proton therapy
journal, March 2012
  • Min, Chul Hee; Lee, Han Rim; Kim, Chan Hyeong
  • Medical Physics, Vol. 39, Issue 4, p. 2100-2107
  • DOI: 10.1118/1.3694098

Heavy-ion tumor therapy: Physical and radiobiological benefits
journal, February 2010
  • Schardt, Dieter; Elsässer, Thilo; Schulz-Ertner, Daniela
  • Reviews of Modern Physics, Vol. 82, Issue 1, p. 383-425
  • DOI: 10.1103/RevModPhys.82.383

Prompt gamma imaging with a slit camera for real-time range control in proton therapy
journal, May 2012
  • Smeets, J.; Roellinghoff, F.; Prieels, D.
  • Physics in Medicine and Biology, Vol. 57, Issue 11, p. 3371-3405
  • DOI: 10.1088/0031-9155/57/11/3371

Coded aperture computed tomography
conference, August 2009
  • Choi, Kerkil; Brady, David J.; Rogers, Stanley
  • Adaptive Coded Aperture Imaging, Non-Imaging, and Unconventional Imaging Sensor Systems, Vol. 7468
  • DOI: 10.1117/12.825277

In-beam PET measurements of β+ radioactivity induced by proton beams
journal, November 2001
  • Parodi, K.; Enghardt, W.; Haberer, T.
  • Physics in Medicine and Biology, Vol. 47, Issue 1, p. 21-36
  • DOI: 10.1088/0031-9155/47/1/302

Coded aperture imaging: a Fourier space analysis
journal, January 1987

A Tracking Compton-Scattering Imaging System for Hadron Therapy Monitoring
journal, February 2010
  • Frandes, Mirela; Zoglauer, Andreas; Maxim, Voichita
  • IEEE Transactions on Nuclear Science, Vol. 57, Issue 1, p. 144-150
  • DOI: 10.1109/TNS.2009.2031679

Compressive coded aperture superresolution image reconstruction
conference, March 2008
  • Marcia, Roummel F.; Willett, Rebecca M.
  • Acoustics, Speech and Signal Processing, 2008. ICASSP 2008. IEEE International Conference on
  • DOI: 10.1109/ICASSP.2008.4517739

Optimal coded aperture patterns for improved SNR in nuclear medicine imaging
journal, December 2001
  • Accorsi, Roberto; Gasparini, Francesca; Lanza, Richard C
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 474, Issue 3, p. 273-284
  • DOI: 10.1016/S0168-9002(01)01326-2

Prompt gamma detection for range verification in proton therapy
journal, March 2012
  • Kurosawa, Shunsuke; Kubo, Hidetoshi; Ueno, Kazuki
  • Current Applied Physics, Vol. 12, Issue 2, p. 364-368
  • DOI: 10.1016/j.cap.2011.07.027

Real-time prompt gamma monitoring in spot-scanning proton therapy using imaging through a knife-edge-shaped slit
journal, December 2011
  • Bom, Victor; Joulaeizadeh, Leila; Beekman, Freek
  • Physics in Medicine and Biology, Vol. 57, Issue 2, p. 297-308
  • DOI: 10.1088/0031-9155/57/2/297