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Title: System and method for dose verification and gamma ray imaging in ion beam therapy

Abstract

This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.

Inventors:
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1415032
Patent Number(s):
9849307
Application Number:
14/886,862
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61N - ELECTROTHERAPY
G - PHYSICS G21 - NUCLEAR PHYSICS G21K - TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Oct 19
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY

Citation Formats

Mihailescu, Lucian. System and method for dose verification and gamma ray imaging in ion beam therapy. United States: N. p., 2017. Web.
Mihailescu, Lucian. System and method for dose verification and gamma ray imaging in ion beam therapy. United States.
Mihailescu, Lucian. Tue . "System and method for dose verification and gamma ray imaging in ion beam therapy". United States. https://www.osti.gov/servlets/purl/1415032.
@article{osti_1415032,
title = {System and method for dose verification and gamma ray imaging in ion beam therapy},
author = {Mihailescu, Lucian},
abstractNote = {This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {12}
}

Works referenced in this record:

Method and apparatus for real time imaging and monitoring of radiotherapy beams
patent, November 2011


Hadron Radiation Installation and Verification Method
patent-application, October 2015


High Energy Radiation Detecting Apparatus and Method
patent-application, December 2015


Development of array-type prompt gamma measurement system for in vivo range verification in proton therapy
journal, March 2012


Prompt gamma imaging with a slit camera for real-time range control in proton therapy
journal, May 2012


Coded aperture computed tomography
conference, August 2009

  • Choi, Kerkil; Brady, David J.; Rogers, Stanley
  • Adaptive Coded Aperture Imaging, Non-Imaging, and Unconventional Imaging Sensor Systems, Vol. 7468
  • https://doi.org/10.1117/12.825277

In-beam PET measurements of β+ radioactivity induced by proton beams
journal, November 2001


Coded aperture imaging: a Fourier space analysis
journal, January 1987


A Tracking Compton-Scattering Imaging System for Hadron Therapy Monitoring
journal, February 2010


Compressive coded aperture superresolution image reconstruction
conference, March 2008


Optimal coded aperture patterns for improved SNR in nuclear medicine imaging
journal, December 2001

  • Accorsi, Roberto; Gasparini, Francesca; Lanza, Richard C
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 474, Issue 3, p. 273-284
  • https://doi.org/10.1016/S0168-9002(01)01326-2

Prompt gamma detection for range verification in proton therapy
journal, March 2012


Real-time prompt gamma monitoring in spot-scanning proton therapy using imaging through a knife-edge-shaped slit
journal, December 2011