Production of alpha-hydroxy carboxylic acids and esters from higher sugars using tandem catalyst systems

Title: Production of alpha-hydroxy carboxylic acids and esters from higher sugars using tandem catalyst systems

The present disclosure is directed to methods and composition used in the preparation of alpha-hydroxy carboxylic acids and esters from higher sugars using a tandem catalyst system comprising retro-aldol catalysts and Lewis acid catalysts. In some embodiments, these alpha-hydroxy carboxylic acids may be prepared from pentoses and hexoses. The retro-aldol and Lewis catalysts may be characterized by their respective ability to catalyze a 1,2-carbon shift reaction and a 1,2-hydride shift reaction on an aldose or ketose substrate.

Inventors:: Orazov, Marat; Davis, Mark E.

Issue Date:: 2017-11-07

OSTI Identifier:: 1407952

Assignee:: California Institute of Technology EFRC

Patent Number(s):: 9,809,528

Application Number:: 15/207,822

Contract Number:: SC0001004

Resource Relation:: Patent File Date: 2016 Jul 12

Research Org:: California Institute of Technology, Pasadena, CA (United States)

Sponsoring Org:: USDOE

Country of Publication:: United States

Language:: English

Subject:: 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

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