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Title: Method for detection of antibodies for metallic elements

Abstract

An apparatus and method for detecting antibodies specific to non-protein antigens. The apparatus is an immunological plate containing a plurality of plastic projections coated with a non-protein material. Assays utilizing the plate are capable of stabilizing the non-protein antigens with detection levels for antibodies specific to the antigens on a nanogram level. A screening assay with the apparatus allows for early detection of exposure to non-protein materials. Specifically metallic elements are detected. 10 figures.

Inventors:
; ;
Issue Date:
Research Org.:
Rockwell International Corp
OSTI Identifier:
140714
Patent Number(s):
5,266,499
Assignee:
Dept. of Energy, Washington, DC (United States)
DOE Contract Number:  
AC04-76DP03533
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 30 Nov 1993
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; 56 BIOLOGY AND MEDICINE, APPLIED STUDIES; METALS; IMMUNOASSAY; LABORATORY EQUIPMENT; DESIGN; ANTIBODIES

Citation Formats

Barrick, C W, Clarke, S M, and Nordin, C W. Method for detection of antibodies for metallic elements. United States: N. p., 1993. Web.
Barrick, C W, Clarke, S M, & Nordin, C W. Method for detection of antibodies for metallic elements. United States.
Barrick, C W, Clarke, S M, and Nordin, C W. Tue . "Method for detection of antibodies for metallic elements". United States.
@article{osti_140714,
title = {Method for detection of antibodies for metallic elements},
author = {Barrick, C W and Clarke, S M and Nordin, C W},
abstractNote = {An apparatus and method for detecting antibodies specific to non-protein antigens. The apparatus is an immunological plate containing a plurality of plastic projections coated with a non-protein material. Assays utilizing the plate are capable of stabilizing the non-protein antigens with detection levels for antibodies specific to the antigens on a nanogram level. A screening assay with the apparatus allows for early detection of exposure to non-protein materials. Specifically metallic elements are detected. 10 figures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1993},
month = {11}
}