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Title: Protection against herbivores

The present invention relates to genes, proteins and methods comprising molecules that alter amino acid levels. In one embodiment, the present invention relates to altering guanidino substrate hydrolysis activities in plants, arthropods and microorganisms using molecules within the arginase family and other molecules that alter an amino acid levels. In ones embodiment, the present invention relates to altering threonine substrate deamination and dehydration activities in plants, arthropods and microorganisms using molecules within the threonine deaminase family and other molecules that alter amino acid levels. In one embodiment, the present invention relates to using genes, proteins and methods comprising arginase or threonine deaminase for altering the pathophysiology of plants, arthropods and microorganisms. In a preferred embodiment, the present invention relates to altering guanidino substrate hydrolysis activity in plants, arthropods, and microorganisms using arginase. In another preferred embodiment, the invention relates to altering threonine substrated deamination and dehydration activity in plants, arthropods, and microorganisms using threonine deaminase. In some embodiments, the invention related to overexpression and increased activity of arginase, threonine deaminase and a proteinase inhibitor.
Inventors:
;
Issue Date:
OSTI Identifier:
1404940
Assignee:
Board of Trustees of Michigan State University CHO
Patent Number(s):
9,796,984
Application Number:
14/490,457
Contract Number:
FG02-91ER20021
Resource Relation:
Patent File Date: 2014 Sep 18
Research Org:
Board of Trustees of Michigan State University, East Lansing, MI (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Other works cited in this record:

Methods of optimizing substrate pools and biosynthesis of poly-.beta.-hydroxybutyrate-co-poly-.beta.-hydroxyvalerate in bacteria and plants
patent, September 1999

Protection against herbivores
patent, October 2014

Expressed sequences of arabidopsis thaliana
patent-application, June 2003

Polynucleotides and polypeptides, materials incorporating them and methods for using them
patent-application, July 2003

Methods for stimulating nervous system regeneration and repair by regulating arginase I and polyamine synthesis
patent-application, November 2003

Methods and compositions for producing plants and microorganisms that express feedback insensitive threonine dehydratase/deaminase
patent-application, January 2004

Protection against herbivores
patent-application, January 2009

Regulation of Plant Arginase by Wounding, Jasmonate, and the Phytotoxin Coronatine
journal, August 2004
  • Chen, Hui; McCaig, Bonnie C.; Melotto, Maeli
  • Journal of Biological Chemistry, Vol. 279, Issue 44, p. 45998-46007
  • DOI: 10.1074/jbc.M407151200

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