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Title: Host cells and methods for production of isobutanol

Abstract

Provided herein are recombinant yeast host cells and methods for their use for production of isobutanol. Yeast host cells provided comprise an isobutanol biosynthetic pathway and at least one of reduced or eliminated aldehyde dehydrogenase activity, reduced or eliminated acetolactate reductase activity; or a heterologous polynucleotide encoding a polypeptide having ketol-acid reductoisomerase activity.

Inventors:
; ; ; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Butamax Advanced Biofuels LLC, Wilmington, DE (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1400243
Patent Number(s):
9,790,521
Application Number:
13/428,585
Assignee:
Butamax Advanced Biofuels LLC ARPA-E
DOE Contract Number:  
AR0000006
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Mar 23
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Anthony, Larry Cameron, He, Hongxian, Huang, Lixuan Lisa, Okeefe, Daniel P., Kruckeberg, Arthur Leo, Li, Yougen, Maggio-Hall, Lori, McElvain, Jessica, Nelson, Mark J., Patnaik, Ranjan, and Rothman, Steven Cary. Host cells and methods for production of isobutanol. United States: N. p., 2017. Web.
Anthony, Larry Cameron, He, Hongxian, Huang, Lixuan Lisa, Okeefe, Daniel P., Kruckeberg, Arthur Leo, Li, Yougen, Maggio-Hall, Lori, McElvain, Jessica, Nelson, Mark J., Patnaik, Ranjan, & Rothman, Steven Cary. Host cells and methods for production of isobutanol. United States.
Anthony, Larry Cameron, He, Hongxian, Huang, Lixuan Lisa, Okeefe, Daniel P., Kruckeberg, Arthur Leo, Li, Yougen, Maggio-Hall, Lori, McElvain, Jessica, Nelson, Mark J., Patnaik, Ranjan, and Rothman, Steven Cary. Tue . "Host cells and methods for production of isobutanol". United States. https://www.osti.gov/servlets/purl/1400243.
@article{osti_1400243,
title = {Host cells and methods for production of isobutanol},
author = {Anthony, Larry Cameron and He, Hongxian and Huang, Lixuan Lisa and Okeefe, Daniel P. and Kruckeberg, Arthur Leo and Li, Yougen and Maggio-Hall, Lori and McElvain, Jessica and Nelson, Mark J. and Patnaik, Ranjan and Rothman, Steven Cary},
abstractNote = {Provided herein are recombinant yeast host cells and methods for their use for production of isobutanol. Yeast host cells provided comprise an isobutanol biosynthetic pathway and at least one of reduced or eliminated aldehyde dehydrogenase activity, reduced or eliminated acetolactate reductase activity; or a heterologous polynucleotide encoding a polypeptide having ketol-acid reductoisomerase activity.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {10}
}

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