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Title: Methods for the selective detection of alkyne-presenting molecules and related compositions and systems

Provided herein are methods for selectively detecting an alkyne-presenting molecule in a sample and related detection reagents, compositions, methods and systems. The methods include contacting a detection reagent with the sample for a time and under a condition to allow binding of the detection reagent to the one or more alkyne-presenting molecules possibly present in the matrix to the detection reagent. The detection reagent includes an organic label moiety presenting an azide group. The binding of the azide group to the alkyne-presenting molecules results in emission of a signal from the organic label moiety.
Inventors:
;
Issue Date:
OSTI Identifier:
1400219
Assignee:
Lawrence Livermore National Security, LLC LLNL
Patent Number(s):
9,791,463
Application Number:
14/201,530
Contract Number:
AC52-07NA27344
Resource Relation:
Patent File Date: 2014 Mar 07
Research Org:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

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