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Title: Site-specific incorporation of redox active amino acids into proteins

Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate redox active amino acids into proteins are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with redox active amino acids using these orthogonal pairs.
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Issue Date:
OSTI Identifier:
The Scripps Research Institute CHO
Patent Number(s):
Application Number:
Contract Number:
Resource Relation:
Patent File Date: 2012 Jan 05
Research Org:
The Scripps Research Inst., La Jolla, CA (United States)
Sponsoring Org:
Country of Publication:
United States

Other works cited in this record:

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Methods and compositions for the production of orthogonal tRNA-aminoacyltRNA synthetase pairs
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Site-Specific Incorporation of a Redox-Active Amino Acid into Proteins
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