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Title: Method and system for formation and withdrawal of a sample from a surface to be analyzed

A method and system for formation and withdrawal of a sample from a surface to be analyzed utilizes a collection instrument having a port through which a liquid solution is conducted onto the surface to be analyzed. The port is positioned adjacent the surface to be analyzed, and the liquid solution is conducted onto the surface through the port so that the liquid solution conducted onto the surface interacts with material comprising the surface. An amount of material is thereafter withdrawn from the surface. Pressure control can be utilized to manipulate the solution balance at the surface to thereby control the withdrawal of the amount of material from the surface. Furthermore, such pressure control can be coordinated with the movement of the surface relative to the port of the collection instrument within the X-Y plane.
Inventors:
;
Issue Date:
OSTI Identifier:
1397242
Assignee:
UT-BATTELLE, LLC ORNL
Patent Number(s):
9,779,926
Application Number:
14/245,324
Contract Number:
AC05-00OR22725
Resource Relation:
Patent File Date: 2014 Apr 04
Research Org:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
99 GENERAL AND MISCELLANEOUS; 36 MATERIALS SCIENCE

Other works cited in this record:

Multiple sample introduction mass spectrometry
patent, March 2001

Ultra high throughput sampling and analysis systems and methods
patent, September 2003

Sampling probe for microarray read out using electrospray mass spectrometry
patent, October 2004

Film-forming method, film-forming apparatus and liquid film drying apparatus
patent-application, March 2002

System and method for dispensing liquids
patent-application, May 2003

Sampling probe for microarray read out using electrospray mass spectrometry
patent-application, October 2003

Exposure apparatus, exposure method, and device fabrication method
patent-application, April 2006

Enclosed desorption electrospray ionization
patent-application, July 2008

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