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Title: System and method for detecting components of a mixture including a valving scheme for competition assays

Examples are described including measurement systems for conducting competition assays. A first chamber of an assay device may be loaded with a sample containing a target antigen. The target antigen in the sample may be allowed to bind to antibody-coated beads in the first chamber. A control layer separating the first chamber from a second chamber may then be opened to allow a labeling agent loaded in a first portion of the second chamber to bind to any unoccupied sites on the antibodies. A centrifugal force may then be applied to transport the beads through a density media to a detection region for measurement by a detection unit.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1393511
Assignee:
National Technology & Engineering Solutions of Sandia, LLC NNSA
Patent Number(s):
9,766,230
Application Number:
15/616,740
Contract Number:
NA0003525
Resource Relation:
Patent File Date: 2017 Jun 07
Research Org:
National Technology & Engineering Solutions of Sandia, LLC., Albuquerque, NM (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING; 59 BASIC BIOLOGICAL SCIENCES; 47 OTHER INSTRUMENTATION

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