Genetically modified yeast species, and fermentation processes using genetically modified yeast
Abstract
Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.
- Inventors:
- Issue Date:
- Research Org.:
- Cargill Incorporated, Wayzata, MN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1390173
- Patent Number(s):
- 9758799
- Application Number:
- 15/201,913
- Assignee:
- Cargill Incorporated
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- FC07-02ID14349
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2016 Jul 05
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, and Ruohonen, Laura. Genetically modified yeast species, and fermentation processes using genetically modified yeast. United States: N. p., 2017.
Web.
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, & Ruohonen, Laura. Genetically modified yeast species, and fermentation processes using genetically modified yeast. United States.
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, and Ruohonen, Laura. Tue .
"Genetically modified yeast species, and fermentation processes using genetically modified yeast". United States. https://www.osti.gov/servlets/purl/1390173.
@article{osti_1390173,
title = {Genetically modified yeast species, and fermentation processes using genetically modified yeast},
author = {Rajgarhia, Vineet and Koivuranta, Kari and Penttila, Merja and Ilmen, Marja and Suominen, Pirkko and Aristidou, Aristos and Miller, Christopher Kenneth and Olson, Stacey and Ruohonen, Laura},
abstractNote = {Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 12 00:00:00 EDT 2017},
month = {Tue Sep 12 00:00:00 EDT 2017}
}
Works referenced in this record:
Xylose utilization by recombinant yeasts
patent, February 1999
- Hallborn, Johan; Penttila, Merja; Ojamo, Heikki
- US Patent Document 5,866,382
Genetically engineered yeast and mutants thereof for the efficient fermentation of lignocellulose hydrolysates
patent, June 2002
- Träff, K. L.; Cordero Otero, R. R.; Van Zyl, W. H.
- US Patent Document 6,410,302
Xylose isomerase with improved properties
patent, November 2002
- Otero, Ricardo Román Cordero; Gárdonyi, Márk; Hahn-Hägerdal, Bärbel
- US Patent Document 6,475,768
Production of ethanol from xylose
patent, June 2003
- Hallborn, Johan; Penttila, Merja; Ojamo, Heikki
- US Patent Document 6,582,944
Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same
patent, January 2012
- Suominen, Pirkko; Aristidou, Aristos; Pentilla, Merja
- US Patent Document 8,097,448
Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells
patent, March 2012
- Miller, Matthew; Suominen, Pirkko; Aristidou, Aristos
- US Patent Document 8,137,953
Cytosolic isobutanol pathway localization for the production of isobutanol
patent, July 2012
- Urano, Jun; Dundon, Catherine Asleson
- US Patent Document 8,232,089