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Title: Array-based detection of genetic alterations associated with disease

The present invention relates to DNA sequences from regions of copy number change on chromosome 20. The sequences can be used in hybridization methods for the identification of chromosomal abnormalities associated with various diseases.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1379191
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA LBNL
Patent Number(s):
9,753,035
Application Number:
11/900,648
Contract Number:
AC03-76SF00098
Resource Relation:
Patent File Date: 2007 Sep 11
Research Org:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES

Works referenced in this record:

Molecular heterogeneity at the breakpoints of smaller 20q deletions
journal, September 1994

Comparative genomic hybridization of ductal carcinoma in situ of the breast—evidence of multiple genetic pathways
journal, March 1999

Co-amplification of erbB2, topoisomerase II α and retinoic acid receptor α genes in breast cancer and allelic loss at topoisomerase I on chromosome 20
journal, January 1993