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Title: Cells and methods for producing fatty alcohols

Recombinant cells and methods for improved yield of fatty alcohols. The recombinant cells harbor a recombinant thioesterase gene, a recombinant acyl-CoA synthetase gene, and a recombinant acyl-CoA reductase gene. In addition, a gene product from one or more of an acyl-CoA dehydrogenase gene, an enoyl-CoA hydratase gene, a 3-hydroxyacyl-CoA dehydrogenase gene, and a 3-ketoacyl-CoA thiolase gene in the recombinant cells is functionally deleted. Culturing the recombinant cells produces fatty alcohols at high yields.
Inventors:
;
Issue Date:
OSTI Identifier:
1371919
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION CHO
Patent Number(s):
9,708,630
Application Number:
14/509,408
Contract Number:
FC02-07ER64494
Resource Relation:
Patent File Date: 2014 Oct 08
Research Org:
WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

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