Variants of glycoside hydrolases
Abstract
The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.
- Inventors:
- Issue Date:
- Research Org.:
- National Renewable Energy Lab. (NREL), Golden, CO (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1369226
- Patent Number(s):
- 9,701,951
- Application Number:
- 14/475,639
- Assignee:
- Novozymes, Inc.
- DOE Contract Number:
- AC36-98GO10337
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2014 Sep 03
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Teter, Sarah, Ward, Connie, Cherry, Joel, Jones, Aubrey, Harris, Paul, and Yi, Jung. Variants of glycoside hydrolases. United States: N. p., 2017.
Web.
Teter, Sarah, Ward, Connie, Cherry, Joel, Jones, Aubrey, Harris, Paul, & Yi, Jung. Variants of glycoside hydrolases. United States.
Teter, Sarah, Ward, Connie, Cherry, Joel, Jones, Aubrey, Harris, Paul, and Yi, Jung. Tue .
"Variants of glycoside hydrolases". United States. https://www.osti.gov/servlets/purl/1369226.
@article{osti_1369226,
title = {Variants of glycoside hydrolases},
author = {Teter, Sarah and Ward, Connie and Cherry, Joel and Jones, Aubrey and Harris, Paul and Yi, Jung},
abstractNote = {The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {7}
}
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