Nanolipoprotein particles comprising hydrogenases and related products, methods and systems

Baker, Sarah E.; Chromy, Brett A.; Henderson, Paul; Hoeprich, Paul D.

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Title: Nanolipoprotein particles comprising hydrogenases and related products, methods and systems

Abstract

Provided herein are nanolipoprotein particles that comprise a membrane associated hydrogenase and related assemblies, devices, methods and systems.

Inventors:: Baker, Sarah E.; Chromy, Brett A.; Henderson, Paul; Hoeprich, Jr., Paul D.

Issue Date:: Tue Jun 27 00:00:00 EDT 2017

Research Org.:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1366761

Patent Number(s):: 9688718

Application Number:: 12/352,472

Assignee:: Lawrence Livermore National Security, LLC

Patent Classifications (CPCs):: C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C07K1/145 - {by extraction or solubilisation}

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N11/02 - Enzymes or microbial cells immobilised on or in an organic carrier

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P3/00 - Preparation of elements or inorganic compounds except carbon dioxide {

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S977/799 - Containing biological material

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DOE Contract Number:: AC52-07NA27344

Resource Type:: Patent

Resource Relation:: Patent File Date: 2009 Jan 12

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Citation Formats


                    Baker, Sarah E., Chromy, Brett A., Henderson, Paul, and Hoeprich, Jr., Paul D. Nanolipoprotein particles comprising hydrogenases and related products, methods and systems.  United States: N. p., 2017. 
        Web.

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                    Baker, Sarah E., Chromy, Brett A., Henderson, Paul, & Hoeprich, Jr., Paul D. Nanolipoprotein particles comprising hydrogenases and related products, methods and systems.  United States.

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                    Baker, Sarah E., Chromy, Brett A., Henderson, Paul, and Hoeprich, Jr., Paul D. Tue .  
        "Nanolipoprotein particles comprising hydrogenases and related products, methods and systems".  United States.  https://www.osti.gov/servlets/purl/1366761.

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@article{osti_1366761,

  title        = {Nanolipoprotein particles comprising hydrogenases and related products, methods and systems},

  author       = {Baker, Sarah E. and Chromy, Brett A. and Henderson, Paul and Hoeprich, Jr., Paul D.},

  abstractNote = {Provided herein are nanolipoprotein particles that comprise a membrane associated hydrogenase and related assemblies, devices, methods and systems.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Jun 27 00:00:00 EDT 2017},

  month        = {Tue Jun 27 00:00:00 EDT 2017}

}

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Stable-isotope probing as a tool in microbial ecology
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Title: Nanolipoprotein particles comprising hydrogenases and related products, methods and systems

Abstract

Citation Formats

Muramyldipeptide derivatives patent, March 1982

Method for making liposomes of enhanced entrapping capacity toward foreign substances to be encapsulated patent, February 1995

Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration patent, August 2001

Membrane scaffold proteins patent, May 2006

Membrane scaffold proteins patent, August 2006

Copper-catalysed ligation of azides and acetylenes patent, May 2008

Surface plasmon resonance systems and methods having a variable charge density layer patent, March 2006

Cell-free synthesis of membrane bound polypeptides patent, May 2012

Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification patent, December 2014

Nanolipoprotein particles comprising a natural rubber biosynthetic enzyme complex and related products, methods and systems patent, April 2016

Apolipoprotein A-I mimics patent, July 2016

Photothermal detection of nucleic acid hybridization patent-application, September 2004

Membrane scaffold proteins patent-application, August 2005

Method to ameliorate osteolysis and metastasis patent-application, November 2005

Nanoparticle-Based vaccine delivery system containing adjuvant patent-application, August 2006

Membrane scaffold proteins and tethered membrane proteins patent-application, September 2006

Synthetic single domain polypeptides mimicking apolipoprotein E and methods of use patent-application, May 2007

Nanoparticle-based vaccine delivery system containing adjuvant patent-application, May 2008

Methods and Systems for Monitoring Production of a Target Protein In a Nanolipoprotein Particle patent-application, May 2009

Nanolipoprotein Particles Comprising Hydrogenases and Related Products, Methods and Systems patent-application, July 2009

Nanolipoprotein Particles And Related Methods And Systems For Protein Capture, Solubilization, And/Or Purification patent-application, July 2009

Functionalized Platform For Arrays Configured For Optical Detection Of Targets And Related Arrays, Methods And Systems patent-application, August 2009

Photocatalytic Hydrogen Production And Polypeptides Capable Of Same patent-application, August 2010

Methods and Systems for Producing Nanolipoprotein Particles patent-application, March 2011

Modified Human Apolipoprotein A-1 and Their Uses patent-application, July 2011

In Vitro Protein Synthesis Systems for Membrane Proteins that Include Adolipoproteins and Phospholipid Adolipoprotein Particles patent-application, August 2011

Synthetic Apolipoprotein E Mimicking Polypeptides and Methods of Use patent-application, September 2012

Atomic force microscopy differentiates discrete size distributions between membrane protein containing and empty nanolipoprotein particles journal, March 2009

Functional Cell-free Synthesis of a Seven Helix Membrane Protein: In situ Insertion of Bacteriorhodopsin into Liposomes journal, August 2007

Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs journal, June 2006

Different Apolipoproteins Impact Nanolipoprotein Particle Formation journal, November 2007

Reconstitution and Imaging of a Membrane Protein in a Nanometer-Size Phospholipid Bilayer journal, September 1998

Carboxyl-Terminal Domain of Human Apolipoprotein E: Expression, Purification, and Crystallization journal, November 1999

Functional Characterization of Apolipoprotein E Isoforms Overexpressed in Escherichia coli journal, July 1999

Structural Basis for Thermal Stability of Human Low-Density Lipoprotein journal, March 2005

High level cell-free expression and specific labeling of integral membrane proteins journal, February 2004

Cell-free expression as an emerging technique for the large scale production of integral membrane protein journal, September 2006

Evaluation of detergents for the soluble expression of α-helical and β-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system journal, November 2005

Chemoselective Attachment of Biologically Active Proteins to Surfaces by Expressed Protein Ligation and Its Application for “Protein Chip” Fabrication journal, November 2004

Comparison of Multiplexed Techniques for Detection of Bacterial and Viral Proteins journal, August 2004

Conformational Reorganization of the Four-helix Bundle of Human Apolipoprotein E in Binding to Phospholipid journal, May 2000

Electron microscopic study on reassembly of plasma high density apoprotein with various lipids journal, November 1971

Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers journal, November 2003

A novel approach for biohydrogen production journal, September 2006

From The Cover: Electrocatalytic hydrogen oxidation by an enzyme at high carbon monoxide or oxygen levels journal, October 2005

High-Yield Hydrogen Production from Starch and Water by a Synthetic Enzymatic Pathway journal, May 2007

In vitro hydrogen production by glucose dehydrogenase and hydrogenase journal, July 1996

Enzymatic production of biohydrogen: Biotechnology journal, June 2000

Immobilization of Active Hydrogenases by Encapsulation in Polymeric Porous Gels journal, October 2005

Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins journal, August 2002

Nanodiscs for Immobilization of Lipid Bilayers and Membrane Receptors: Kinetic Analysis of Cholera Toxin Binding to a Glycolipid Receptor journal, August 2008

Investigating and Exploiting the Electrocatalytic Properties of Hydrogenases journal, October 2007

Peptide stabilized amphotericin B nanodisks journal, April 2007

Negative and positive ion matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry and positive ion nano‐electrospray ionization quadrupole ion trap mass spectrometry of peptidoglycan fragments isolated from various Bacillus species journal, February 2001

A simple energy-conserving system: Proton reduction coupled to proton translocation journal, June 2003

In-depth analysis of the membrane and cytosolic proteome of red blood cells journal, August 2006

Charge‐reduced nano electrospray ionization combined with differential mobility analysis of peptides, proteins, glycoproteins, noncovalent protein complexes and viruses journal, September 2001

High yield cell-free production of integral membrane proteins without refolding or detergents journal, May 2008

Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase journal, April 2002

Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems journal, January 2003

The growing impact of click chemistry on drug discovery journal, December 2003

Large-scale profiling of protein palmitoylation in mammalian cells journal, January 2009

The Efficiency of Light-Directed Synthesis of DNA Arrays on Glass Substrates journal, June 1997

Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array journal, October 1999

Bacterial Rhodopsin: Evidence for a New Type of Phototrophy in the Sea journal, September 2000

Specific Interaction and Two-Dimensional Crystallization of Histidine Tagged Yeast RNA Polymerase I on Nickel-Chelating Lipids journal, March 1998

Characterization and Purification of Polydisperse Reconstituted Lipoproteins and Nanolipoprotein Particles journal, July 2009

CpG oligodeoxynucleotides as DNA adjuvants in vertebrates and their applications in immunotherapy journal, October 2006

Attaching histidine-tagged peptides and proteins to lipid-based carriers through use of metal-ion-chelating lipids journal, December 2002

Stability of pressure-extruded liposomes made from archaeobacterial ether lipids journal, November 1994

Surface changes induced by osmotic shrinkage on large unilamellar vesicles journal, November 1996

Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice journal, February 2000

Conjugation to Nickel-Chelating Nanolipoprotein Particles Increases the Potency and Efficacy of Subunit Vaccines to Prevent West Nile Encephalitis journal, June 2010

Adjuvants for human vaccines—current status, problems and future prospects journal, January 1995

Influence of liposome charge and composition on their interaction with human blood serum proteins journal, January 1993

Steric stabilization of phospholipid vesicles by block copolymers Vesicle flocculation and osmotic swelling caused by monovalent and divalent cations journal, January 1998

Two-Dimensional Crystallization of Histidine-Tagged, HIV-1 Reverse Transcriptase Promoted by a Novel Nickel-Chelating Lipid journal, September 1994

Muramyldipeptide derivatives
patent, March 1982

Method for making liposomes of enhanced entrapping capacity toward foreign substances to be encapsulated
patent, February 1995

Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration
patent, August 2001

Membrane scaffold proteins
patent, May 2006

Membrane scaffold proteins
patent, August 2006

Copper-catalysed ligation of azides and acetylenes
patent, May 2008

Surface plasmon resonance systems and methods having a variable charge density layer
patent, March 2006

Cell-free synthesis of membrane bound polypeptides
patent, May 2012

Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification
patent, December 2014

Nanolipoprotein particles comprising a natural rubber biosynthetic enzyme complex and related products, methods and systems
patent, April 2016

Apolipoprotein A-I mimics
patent, July 2016

Photothermal detection of nucleic acid hybridization
patent-application, September 2004

Membrane scaffold proteins
patent-application, August 2005

Method to ameliorate osteolysis and metastasis
patent-application, November 2005

Nanoparticle-Based vaccine delivery system containing adjuvant
patent-application, August 2006

Membrane scaffold proteins and tethered membrane proteins
patent-application, September 2006

Synthetic single domain polypeptides mimicking apolipoprotein E and methods of use
patent-application, May 2007

Nanoparticle-based vaccine delivery system containing adjuvant
patent-application, May 2008

Methods and Systems for Monitoring Production of a Target Protein In a Nanolipoprotein Particle
patent-application, May 2009

Nanolipoprotein Particles Comprising Hydrogenases and Related Products, Methods and Systems
patent-application, July 2009

Nanolipoprotein Particles And Related Methods And Systems For Protein Capture, Solubilization, And/Or Purification
patent-application, July 2009

Functionalized Platform For Arrays Configured For Optical Detection Of Targets And Related Arrays, Methods And Systems
patent-application, August 2009

Photocatalytic Hydrogen Production And Polypeptides Capable Of Same
patent-application, August 2010

Methods and Systems for Producing Nanolipoprotein Particles
patent-application, March 2011

Modified Human Apolipoprotein A-1 and Their Uses
patent-application, July 2011

In Vitro Protein Synthesis Systems for Membrane Proteins that Include Adolipoproteins and Phospholipid Adolipoprotein Particles
patent-application, August 2011

Synthetic Apolipoprotein E Mimicking Polypeptides and Methods of Use
patent-application, September 2012

Atomic force microscopy differentiates discrete size distributions between membrane protein containing and empty nanolipoprotein particles
journal, March 2009

Functional Cell-free Synthesis of a Seven Helix Membrane Protein: In situ Insertion of Bacteriorhodopsin into Liposomes
journal, August 2007

Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs
journal, June 2006

Different Apolipoproteins Impact Nanolipoprotein Particle Formation
journal, November 2007

Reconstitution and Imaging of a Membrane Protein in a Nanometer-Size Phospholipid Bilayer
journal, September 1998

Carboxyl-Terminal Domain of Human Apolipoprotein E: Expression, Purification, and Crystallization
journal, November 1999

Functional Characterization of Apolipoprotein E Isoforms Overexpressed in Escherichia coli
journal, July 1999

Structural Basis for Thermal Stability of Human Low-Density Lipoprotein
journal, March 2005

High level cell-free expression and specific labeling of integral membrane proteins
journal, February 2004

Cell-free expression as an emerging technique for the large scale production of integral membrane protein
journal, September 2006

Evaluation of detergents for the soluble expression of α-helical and β-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system
journal, November 2005

Chemoselective Attachment of Biologically Active Proteins to Surfaces by Expressed Protein Ligation and Its Application for “Protein Chip” Fabrication
journal, November 2004

Comparison of Multiplexed Techniques for Detection of Bacterial and Viral Proteins
journal, August 2004

Conformational Reorganization of the Four-helix Bundle of Human Apolipoprotein E in Binding to Phospholipid
journal, May 2000

Electron microscopic study on reassembly of plasma high density apoprotein with various lipids
journal, November 1971

Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers
journal, November 2003

A novel approach for biohydrogen production
journal, September 2006

From The Cover: Electrocatalytic hydrogen oxidation by an enzyme at high carbon monoxide or oxygen levels
journal, October 2005

High-Yield Hydrogen Production from Starch and Water by a Synthetic Enzymatic Pathway
journal, May 2007

In vitro hydrogen production by glucose dehydrogenase and hydrogenase
journal, July 1996

Enzymatic production of biohydrogen: Biotechnology
journal, June 2000

Immobilization of Active Hydrogenases by Encapsulation in Polymeric Porous Gels
journal, October 2005

Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins
journal, August 2002

Nanodiscs for Immobilization of Lipid Bilayers and Membrane Receptors: Kinetic Analysis of Cholera Toxin Binding to a Glycolipid Receptor
journal, August 2008

Investigating and Exploiting the Electrocatalytic Properties of Hydrogenases
journal, October 2007

Peptide stabilized amphotericin B nanodisks
journal, April 2007

Negative and positive ion matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry and positive ion nano‐electrospray ionization quadrupole ion trap mass spectrometry of peptidoglycan fragments isolated from various Bacillus species
journal, February 2001

A simple energy-conserving system: Proton reduction coupled to proton translocation
journal, June 2003

In-depth analysis of the membrane and cytosolic proteome of red blood cells
journal, August 2006

Charge‐reduced nano electrospray ionization combined with differential mobility analysis of peptides, proteins, glycoproteins, noncovalent protein complexes and viruses
journal, September 2001

High yield cell-free production of integral membrane proteins without refolding or detergents
journal, May 2008

Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase
journal, April 2002

Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems
journal, January 2003

The growing impact of click chemistry on drug discovery
journal, December 2003

Large-scale profiling of protein palmitoylation in mammalian cells
journal, January 2009

The Efficiency of Light-Directed Synthesis of DNA Arrays on Glass Substrates
journal, June 1997

Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array
journal, October 1999

Bacterial Rhodopsin: Evidence for a New Type of Phototrophy in the Sea
journal, September 2000

Specific Interaction and Two-Dimensional Crystallization of Histidine Tagged Yeast RNA Polymerase I on Nickel-Chelating Lipids
journal, March 1998

Characterization and Purification of Polydisperse Reconstituted Lipoproteins and Nanolipoprotein Particles
journal, July 2009

CpG oligodeoxynucleotides as DNA adjuvants in vertebrates and their applications in immunotherapy
journal, October 2006

Attaching histidine-tagged peptides and proteins to lipid-based carriers through use of metal-ion-chelating lipids
journal, December 2002

Stability of pressure-extruded liposomes made from archaeobacterial ether lipids
journal, November 1994

Surface changes induced by osmotic shrinkage on large unilamellar vesicles
journal, November 1996

Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice
journal, February 2000

Conjugation to Nickel-Chelating Nanolipoprotein Particles Increases the Potency and Efficacy of Subunit Vaccines to Prevent West Nile Encephalitis
journal, June 2010

Adjuvants for human vaccines—current status, problems and future prospects
journal, January 1995

Influence of liposome charge and composition on their interaction with human blood serum proteins
journal, January 1993

Steric stabilization of phospholipid vesicles by block copolymers Vesicle flocculation and osmotic swelling caused by monovalent and divalent cations
journal, January 1998

Two-Dimensional Crystallization of Histidine-Tagged, HIV-1 Reverse Transcriptase Promoted by a Novel Nickel-Chelating Lipid
journal, September 1994

Mechanical properties and stability measurement of cholesterol-containing liposome on mica by atomic force microscopy
journal, October 2004

The Vaccine Adjuvant Monophosphoryl Lipid A as a TRIF-Biased Agonist of TLR4
journal, June 2007

The Effects of Deleting the Mouse Neurotensin Receptor NTR1 on Central and Peripheral Responses to Neurotensin
journal, January 2002