Global to push GA events into
skip to main content

Title: System and method for measuring fluorescence of a sample

The present disclosure provides a system and a method for measuring fluorescence of a sample. The sample may be a polymerase-chain-reaction (PCR) array, a loop-mediated-isothermal amplification array, etc. LEDs are used to excite the sample, and a photodiode is used to collect the sample's fluorescence. An electronic offset signal is used to reduce the effects of background fluorescence and the noises from the measurement system. An integrator integrates the difference between the output of the photodiode and the electronic offset signal over a given period of time. The resulting integral is then converted into digital domain for further processing and storage.
Issue Date:
OSTI Identifier:
Lawrence Livermore National Security, LLC LLNL
Patent Number(s):
Application Number:
Contract Number:
Resource Relation:
Patent File Date: 2015 Jan 21
Research Org:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org:
Country of Publication:
United States

Other works cited in this record:

Detection of certain minerals of zinc, tungsten, fluorine, molybdenum, mercury and other metals using photoluminescence
patent, December 1982

Method and apparatus for separating magnetic particles from a solution
patent, July 1997

Manifold with check valve positioned within manifold body
patent, August 2000

Signal processing of an array of sensor elements in a detector
patent, August 2000

Digital offset corrector
patent, August 2001

System and methods for improving signal/noise ratio for signal detectors
patent, June 2007

Fluidics platform and method for sample preparation and analysis
patent, August 2014

System and method for measuring fluorescence of a sample
patent, March 2015

Fluidics platform and method for sample preparation
patent, June 2016

Thermal Cycling System
patent-application, January 2008

Digital intensity suppression for vibration and radiation insensitivity in a fiber optic gyroscope
patent-application, April 2008

Method of Concentrating Beads in a Droplet
patent-application, May 2011

Syringe Filter Cap and Method of Using the Same for Administration of Medication Dosage
patent-application, September 2011

Similar records in DOepatents and OSTI.GOV collections: