Positron emission tomography probe to monitor selected sugar metabolism in vivo
Abstract
The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1346982
- Patent Number(s):
- 9592309
- Application Number:
- 14/399,701
- Assignee:
- The Regents of the University of California
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- SC0001249
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2013 May 09
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; 47 OTHER INSTRUMENTATION
Citation Formats
Witte, Owen, Clark, Peter M., Castillo, Blanca Graciela Flores, Jung, Michael E., and Evdokimov, Nikolai M. Positron emission tomography probe to monitor selected sugar metabolism in vivo. United States: N. p., 2017.
Web.
Witte, Owen, Clark, Peter M., Castillo, Blanca Graciela Flores, Jung, Michael E., & Evdokimov, Nikolai M. Positron emission tomography probe to monitor selected sugar metabolism in vivo. United States.
Witte, Owen, Clark, Peter M., Castillo, Blanca Graciela Flores, Jung, Michael E., and Evdokimov, Nikolai M. Tue .
"Positron emission tomography probe to monitor selected sugar metabolism in vivo". United States. https://www.osti.gov/servlets/purl/1346982.
@article{osti_1346982,
title = {Positron emission tomography probe to monitor selected sugar metabolism in vivo},
author = {Witte, Owen and Clark, Peter M. and Castillo, Blanca Graciela Flores and Jung, Michael E. and Evdokimov, Nikolai M.},
abstractNote = {The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {3}
}
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