Sequestration of carbon dioxide with hydrogen to useful products
Abstract
Provided herein are genetically engineered microbes that include at least a portion of a carbon fixation pathway, and in one embodiment, use molecular hydrogen to drive carbon dioxide fixation. In one embodiment, the genetically engineered microbe is modified to convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof at levels greater than a control microbe. Other products may also be produced. Also provided herein are cell free compositions that convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof. Also provided herein are methods of using the genetically engineered microbes and the cell free compositions.
- Inventors:
- Issue Date:
- Research Org.:
- University of Georgia Research Foundation, Inc. Athens, GA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1346064
- Patent Number(s):
- 9587256
- Application Number:
- 14/426,290
- Assignee:
- University of Georgia Research Foundation, Inc.
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- AR0000081
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2013 Sep 06
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 08 HYDROGEN; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Adams, Michael W. W., Kelly, Robert M., Hawkins, Aaron B., Menon, Angeli Lal, Lipscomb, Gina Lynette Pries, and Schut, Gerrit Jan. Sequestration of carbon dioxide with hydrogen to useful products. United States: N. p., 2017.
Web.
Adams, Michael W. W., Kelly, Robert M., Hawkins, Aaron B., Menon, Angeli Lal, Lipscomb, Gina Lynette Pries, & Schut, Gerrit Jan. Sequestration of carbon dioxide with hydrogen to useful products. United States.
Adams, Michael W. W., Kelly, Robert M., Hawkins, Aaron B., Menon, Angeli Lal, Lipscomb, Gina Lynette Pries, and Schut, Gerrit Jan. Tue .
"Sequestration of carbon dioxide with hydrogen to useful products". United States. https://www.osti.gov/servlets/purl/1346064.
@article{osti_1346064,
title = {Sequestration of carbon dioxide with hydrogen to useful products},
author = {Adams, Michael W. W. and Kelly, Robert M. and Hawkins, Aaron B. and Menon, Angeli Lal and Lipscomb, Gina Lynette Pries and Schut, Gerrit Jan},
abstractNote = {Provided herein are genetically engineered microbes that include at least a portion of a carbon fixation pathway, and in one embodiment, use molecular hydrogen to drive carbon dioxide fixation. In one embodiment, the genetically engineered microbe is modified to convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof at levels greater than a control microbe. Other products may also be produced. Also provided herein are cell free compositions that convert acetyl CoA, molecular hydrogen, and carbon dioxide to 3-hydroxypropionate, 4-hydroxybutyrate, acetyl CoA, or the combination thereof. Also provided herein are methods of using the genetically engineered microbes and the cell free compositions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 07 00:00:00 EST 2017},
month = {Tue Mar 07 00:00:00 EST 2017}
}
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Synthesis of protein with an identification peptide
patent, October 1987
- Hopp, Thomas P.; Bektesh, Susan; Conlon, Paul J.
- US Patent Document 4,703,004
Synthesis of protein with an identification peptide, and hybrid polypeptide incorporating same
patent, November 1988
- Hopp, Thomas P.; Bektesh, Susan; Conlon, Paul J.
- US Patent Document 4,782,137
Process of purifying recombinant proteins and compounds useful in such process
patent, January 1997
- Sharma, Satish
- US Patent Document 5,594,115
Thermophile gene transfer
patent, February 1999
- Weber, J. Mark; Demirjian, David; Casadaban, Malcolm J.
- US Patent Document 5,872,238
Switchable photosystem-II designer algae for photobiological hydrogen production
patent, January 2010
- Lee, James Weifu
- US Patent Document 7,642,405
Hyperphotosynthetic organisms
patent, August 2010
- Devroe, Eric; Kosuri, Sriram; Berry, David Arthur
- US Patent Document 7,785,861
Methods and compositions for the recombinant biosynthesis of n-alkanes
patent, September 2010
- Reppas, Nikos Basil; Ridley, Christian Perry
- US Patent Document 7,794,969
Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
patent, September 2010
- Burk, Mark J.; Schilling, Christophe H.; Burgard, Anthony P.
- US Patent Document 7,803,589
Compositions and methods for 3-hydroxypropionate bio-production from biomass
patent, November 2011
- Lynch, Michael D.
- US Patent Document 8,048,624
Energy production with hyperthermophilic organisms
patent, October 2012
- Remmereit, Jan; Thomm, Michael
- US Patent Document 8,278,087
Method for the combined production of butanol and hydrogen
patent, April 2013
- Claassen, Pieternel A. M.; Budde, Miriam; De Vrije, Geertruida
- US Patent Document 8,420,358
Microorganisms and methods for carbon-efficient biosynthesis of MEK and 2-butanol
patent, April 2013
- Osterhout, Robin E.; Niu, Wei; Burgard, Anthony P.
- US Patent Document 8,420,375
Gene knockout mesophilic and thermophilic organisms, and methods of use thereof
patent, May 2013
- Hogsett, David A.; Rajgarhia, Vineet
- US Patent Document 8,435,770
Microorganisms and methods for conversion of syngas and other carbon sources to useful products
patent, June 2013
- Trawick, John D.; Burk, Mark J.; Burgard, Anthony P.
- US Patent Document 8,470,566
Sporulation-deficient thermophilic microorganisms for the production of ethanol
patent, July 2013
- Atkinson, Anthony; Cripps, Roger; Eley, Kirstin
- US Patent Document 8,486,687
Genetic modification of homolactic thermophilic bacilli
patent, July 2013
- Van Kranenburg, Richard; Van Hartskamp, Mariska; Heintz, Eelco Anthonius Johannes
- US Patent Document 8,497,128
Hydrogen production with photosynthetic organisms and from biomass derived therefrom
patent-application, March 2005
- Berzin, Isaac
- US Patent Application 10/924742; 20050064577
Hyperphotosynthetic Organisms
patent-application, August 2009
- Devroe, Eric James; Kosuri, Sriram; Berry, David Arthur
- US Patent Application 12/268406; 20090203070
Microbiological Production of 3-Hydroxyisobutyric Acid
patent-application, March 2010
- Marx, Achim; Poetter, MArkus; Buchholz, Stefen
- US Patent Application 12/303161; 20100068773 A1
Biological and Chemical Process Utilizing Chemoautotrophic Microorganisms for the Chemosythetic Fixation of Carbon Dioxide and or Other Inorganic Carbon Sources into Organic Compounds, and the Generation of Additional Useful Products
patent-application, May 2010
- Reed, John Stuart
- US Patent Application 12/613550; 20100120104
Methods, systems and compositions for increased microorganism tolerance to and production of 3-hydroxypropionic acid (3-HP)
patent-application, October 2011
- Lipscomb, Tanya E. W.; Lynch, Michael D.; Gill, Ryan T.
- US Patent Application 13/055138; 20110244575
A 3-Hydroxypropionate/4-Hydroxybutyrate Autotrophic Carbon Dioxide Assimilation Pathway in Archaea
journal, December 2007
- Berg, Ivan A.; Kockelkorn, Daniel; Buckel, Wolfgang
- Science, Vol. 318, Issue 5857, p. 1782-1786
The Southeast Collaboratory for Structural Genomics: A High-Throughput Gene to Structure Factory
journal, March 2003
- Adams, Michael W. W.; Dailey, Harry A.; DeLucas, Lawrence J.
- Accounts of Chemical Research, Vol. 36, Issue 3, p. 191-198
The structure and mechanism of iron-hydrogenases
journal, November 1990
- Adams, Michael W. W.
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1020, Issue 2, p. 115-145
Organometallic iron: the key to biological hydrogen metabolism
journal, April 2000
- Adams, Michael W.W.; Stiefel, Edward I.
- Current Opinion in Chemical Biology, Vol. 4, Issue 2, p. 214-220
Identification of Eggshell Membrane Proteins and Purification of Ovotransferrin and β-NAGase from Hen Egg White
journal, January 2006
- Ahlborn, G. J.; Clare, D. A.; Sheldon, B. W.
- The Protein Journal, Vol. 25, Issue 1, p. 71-81
3-Hydroxypropionyl-Coenzyme A Synthetase from Metallosphaera sedula, an Enzyme Involved in Autotrophic CO2 Fixation
journal, December 2007
- Alber, B. E.; Kung, J. W.; Fuchs, G.
- Journal of Bacteriology, Vol. 190, Issue 4, p. 1383-1389
Nickel hydrogenases: in search of the active site
journal, December 1994
- Albracht, Simon P. J.
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1188, Issue 3, p. 167-204
Metabolic engineering of Escherichia coli for 1-butanol production
journal, November 2008
- Atsumi, Shota; Cann, Anthony F.; Connor, Michael R.
- Metabolic Engineering, Vol. 10, Issue 6, p. 305-311
Impact of Molecular Hydrogen on Chalcopyrite Bioleaching by the Extremely Thermoacidophilic Archaeon Metallosphaera sedula
journal, February 2010
- Auernik, K. S.; Kelly, R. M.
- Applied and Environmental Microbiology, Vol. 76, Issue 8, p. 2668-2672
Life in hot acid: pathway analyses in extremely thermoacidophilic archaea
journal, October 2008
- Auernik, Kathryne S.; Cooper, Charlotte R.; Kelly, Robert M.
- Current Opinion in Biotechnology, Vol. 19, Issue 5, p. 445-453
Global analysis of carbohydrate utilization by Lactobacillus acidophilus using cDNA microarrays
journal, February 2006
- Barrangou, R.; Azcarate-Peril, M. A.; Duong, T.
- Proceedings of the National Academy of Sciences, Vol. 103, Issue 10, p. 3816-3821
Generation of New Hydrogen-Recycling Rhizobiaceae Strains by Introduction of a Novel hup Minitransposon
journal, October 2000
- Bascones, E.; Imperial, J.; Ruiz-Argueso, T.
- Applied and Environmental Microbiology, Vol. 66, Issue 10, p. 4292-4299
Autotrophic carbon fixation in archaea
journal, May 2010
- Berg, Ivan A.; Kockelkorn, Daniel; Ramos-Vera, W. Hugo
- Nature Reviews Microbiology, Vol. 8, Issue 6, p. 447-460
Comparison of the X-ray structure of native rubredoxin from pyrococcus furiosus with the NMR structure of the zinc-substituted protein
journal, November 1992
- Blake, Paul R.; Day, Michael W.; Hsu, Barbara T.
- Protein Science, Vol. 1, Issue 11, p. 1522-1525
Solution-state structure by NMR of zinc-substituted rubredoxin from the marine hyperthermophilic archaebacterium pyrococcus furiosus
journal, November 1992
- Blake, Paul R.; Park, Jae-Bum; Zhou, Zhi Hao
- Protein Science, Vol. 1, Issue 11, p. 1508-1521
Purification and characterization of pyruvate ferredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus
journal, January 1993
- Blamey, Jenny M.; Adams, Michael W. W.
- Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, Vol. 1161, Issue 1, p. 19-27
Can Biology Transform Our Energy Future?: ARPA-E infuses innovative research ventures with fresh funds
journal, February 2012
- Blaustein, Richard
- BioScience, Vol. 62, Issue 2, p. 115-119
The Complex Between Hydrogenase-maturation Proteins HypC and HypD is an Intermediate in the Supply of Cyanide to the Active Site Iron of [NiFe]-Hydrogenases
journal, November 2004
- Blokesch, Melanie; Albracht, Simon P. J.; Matzanke, Berthold F.
- Journal of Molecular Biology, Vol. 344, Issue 1, p. 155-167
Maturation of [NiFe]-hydrogenases in Escherichia coli: The HypC Cycle
journal, November 2002
- Blokesch, Melanie; Böck, August
- Journal of Molecular Biology, Vol. 324, Issue 2, p. 287-296
Analysis of the transcarbamoylation-dehydration reaction catalyzed by the hydrogenase maturation proteins HypF and HypE: Hydrogenase maturation protein HypE
journal, July 2004
- Blokesch, Melanie; Paschos, Athanasios; Bauer, Anette
- European Journal of Biochemistry, Vol. 271, Issue 16, p. 3428-3436
Metal insertion into NiFe-hydrogenases
journal, August 2002
- Blokesch, M.; Paschos, A.; Theodoratou, E.
- Biochemical Society Transactions, Vol. 30, Issue 4, p. 674-680
HybF, a Zinc-Containing Protein Involved in NiFe Hydrogenase Maturation
journal, May 2004
- Blokesch, M.; Rohrmoser, M.; Rode, S.
- Journal of Bacteriology, Vol. 186, Issue 9, p. 2603-2611
Extremely thermophilic microorganisms for biomass conversion status and prospects
journal, June 2008
- Blumer-Schuette, Sara E.; Kataeva, Irina; Westpheling, Janet
- Current Opinion in Biotechnology, Vol. 19, Issue 3, p. 210-217
Maturation of Hydrogenases
book, September 2006
- Böck, August; King, Paul W.; Blokesch, Melanie
- Advances in Microbial Physiology, Vol. 51, p. 1-71
Origins and evolution of isoprenoid lipid biosynthesis in archaea
journal, March 2004
- Boucher, Yan; Kamekura, Masahiro; Doolittle, W. Ford
- Molecular Microbiology, Vol. 52, Issue 2, p. 515-527
AMP-forming acetyl-CoA synthetase from the extremely halophilic archaeon Haloarcula marismortui: purification, identification and expression of the encoding gene, and phylogenetic affiliation
journal, June 2005
- Bräsen, Christopher; Schönheit, Peter
- Extremophiles, Vol. 9, Issue 5, p. 355-365
A novel octameric AMP-forming acetyl-CoA synthetase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum
journal, December 2004
- Bräsen, Christopher; Urbanke, Claus; Schönheit, Peter
- FEBS Letters, Vol. 579, Issue 2, p. 477-482
An improved method using acetyl-coenzyme A regeneration for the enzymic inactivation of aminoglycosides prior to sterility testing
journal, October 1982
- Breeze, A.S.; Simpson, Ann M.
- Journal of Applied Bacteriology, Vol. 53, Issue 2, p. 277-284
Genome Sequencing of a Genetically Tractable Pyrococcus furiosus Strain Reveals a Highly Dynamic Genome
journal, May 2012
- Bridger, S. L.; Lancaster, W. A.; Poole, F. L.
- Journal of Bacteriology, Vol. 194, Issue 15, p. 4097-4106
Radical Enzymes in Anaerobes
journal, October 2006
- Buckel, Wolfgang; Golding, Bernard T.
- Annual Review of Microbiology, Vol. 60, Issue 1, p. 27-49
A Phylogenetic Analysis of Aquifex pyrophilus
journal, August 1992
- Burggraf, S.; Olsen, G. J.; Stetter, K. O.
- Systematic and Applied Microbiology, Vol. 15, Issue 3, p. 352-356
The First Agmatine/Cadaverine Aminopropyl Transferase: Biochemical and Structural Characterization of an Enzyme Involved in Polyamine Biosynthesis in the Hyperthermophilic Archaeon Pyrococcus furiosus
journal, June 2007
- Cacciapuoti, G.; Porcelli, M.; Moretti, M. A.
- Journal of Bacteriology, Vol. 189, Issue 16, p. 6057-6067
Engineering Hyperthermophilic Archaeon Pyrococcus furiosus to Overproduce Its Cytoplasmic [NiFe]-Hydrogenase
journal, December 2011
- Chandrayan, Sanjeev K.; McTernan, Patrick M.; Hopkins, R. Christopher
- Journal of Biological Chemistry, Vol. 287, Issue 5, p. 3257-3264
Acetone-butanol-isopropanol production byClostridium beijerinckii (synonym,Clostridium butylicum)
journal, May 1986
- Chen, Jiann-Shin; Hiu, Stephen F.
- Biotechnology Letters, Vol. 8, Issue 5, p. 371-376
Hydrogenesis in hyperthermophilic microorganisms: Implications for biofuels
journal, November 2008
- Chou, Chung-Jung; Jenney, Francis E.; Adams, Michael W.W.
- Metabolic Engineering, Vol. 10, Issue 6, p. 394-404
Impact of Substrate Glycoside Linkage and Elemental Sulfur on Bioenergetics of and Hydrogen Production by the Hyperthermophilic Archaeon Pyrococcus furiosus
journal, September 2007
- Chou, C.-J.; Shockley, K. R.; Conners, S. B.
- Applied and Environmental Microbiology, Vol. 73, Issue 21, p. 6842-6853
The Escherichia coli metal-binding chaperone SlyD interacts with the large subunit of [NiFe]-hydrogenase 3
journal, December 2010
- Chan Chung, Kim C.; Zamble, Deborah B.
- FEBS Letters, Vol. 585, Issue 2, p. 291-294
Functional-Genomics-Based Identification and Characterization of Open Reading Frames Encoding α-Glucoside-Processing Enzymes in the Hyperthermophilic Archaeon Pyrococcus furiosus
journal, December 2007
- Comfort, D. A.; Chou, C.-J.; Conners, S. B.
- Applied and Environmental Microbiology, Vol. 74, Issue 4, p. 1281-1283
Biochemical Analysis of Thermotoga maritima GH36 α-Galactosidase (Tm GalA) Confirms the Mechanistic Commonality of Clan GH-D Glycoside Hydrolases
journal, March 2007
- Comfort, Donald A.; Bobrov, Kirill S.; Ivanen, Dina R.
- Biochemistry, Vol. 46, Issue 11, p. 3319-3330
Strategic biocatalysis with hyperthermophilic enzymes
journal, August 2004
- Comfort, Donald A.; Chhabra, Swapnil R.; Conners, Shannon B.
- Green Chemistry, Vol. 6, Issue 9, p. 459-465
Microbial production of advanced transportation fuels in non-natural hosts
journal, June 2009
- Connor, Michael R.; Liao, James C.
- Current Opinion in Biotechnology, Vol. 20, Issue 3, p. 307-315
Microbial biochemistry, physiology, and biotechnology of hyperthermophilic Thermotoga species
journal, November 2006
- Conners, Shannon B.; Mongodin, Emmanuel F.; Johnson, Matthew R.
- FEMS Microbiology Reviews, Vol. 30, Issue 6, p. 872-905
X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium pyrococcus furiosus
journal, November 1992
- Day, Michael W.; Hsu, Barbara T.; Joshua-Tor, Leemor
- Protein Science, Vol. 1, Issue 11, p. 1494-1507
Growth in sulfidic mineral environments: metal resistance mechanisms in acidophilic micro-organisms
journal, August 2003
- Dopson, Mark; Baker-Austin, Craig; Koppineedi, P. Ram
- Microbiology, Vol. 149, Issue 8, p. 1959-1970
Retrobiosynthetic analysis of carbon fixation in the phototrophic eubacterium Chloroflexus aurantiacus
journal, August 1993
- Eisenreich, Wolfgang; Strauss, Gerhard; Werz, Udo
- European Journal of Biochemistry, Vol. 215, Issue 3, p. 619-632
Influence of divalent cations on the structural thermostability and thermal inactivation kinetics of class II xylose isomerases: Thermostability of class II xylose isomerases
journal, March 2005
- Epting, Kevin L.; Vieille, Claire; Zeikus, J. Gregory
- FEBS Journal, Vol. 272, Issue 6, p. 1454-1464
Labeling and Enzyme Studies of the Central Carbon Metabolism in Metallosphaera sedula
journal, December 2010
- Estelmann, S.; Hugler, M.; Eisenreich, W.
- Journal of Bacteriology, Vol. 193, Issue 5, p. 1191-1200
Molecular characterization of a conserved archaeal copper resistance (cop) gene cluster and its copper-responsive regulator in Sulfolobus solfataricus P2
journal, July 2006
- Ettema, Thijs J. G.; Brinkman, Arie B.; Lamers, Packo P.
- Microbiology, Vol. 152, Issue 7, p. 1969-1979
Pyrococcus furiosus sp. nov. represents a novel genus of marine heterotrophic archaebacteria growing optimally at 100°C
journal, June 1986
- Fiala, Gerhard; Stetter, Karl O.
- Archives of Microbiology, Vol. 145, Issue 1, p. 56-61
Maturation of [NiFe]-hydrogenases in Escherichia coli
journal, January 2007
- Forzi, Lucia; Sawers, R. Gary
- BioMetals, Vol. 20, Issue 3-4, p. 565-578
Evaluation of continuous ethanol fermentation of dilute-acid corn stover hydrolysate using thermophilic anaerobic bacterium Thermoanaerobacter BG1L1
journal, September 2007
- Georgieva, Tania I.; Ahring, Birgitte K.
- Applied Microbiology and Biotechnology, Vol. 77, Issue 1, p. 61-68
Effect of temperature on ethanol tolerance of a thermophilic anaerobic ethanol producer Thermoanaerobacter A10: Modeling and simulation
journal, June 2007
- Georgieva, Tania I.; Skiadas, Ioannis V.; Ahring, Birgitte K.
- Biotechnology and Bioengineering, Vol. 98, Issue 6, p. 1161-1170
Fermentation of 4-aminobutyrate by Clostridium aminobutyricum : cloning of two genes involved in the formation and dehydration of 4-hydroxybutyryl-CoA
journal, August 2000
- Gerhardt, Astrid; Çinkaya, Irfan; Linder, Dietmar
- Archives of Microbiology, Vol. 174, Issue 3, p. 189-199
Structural and transcriptional analyses of a purine nucleotide-binding protein from Pyrococcus furiosus: a component of a novel, membrane-bound multiprotein complex unique to this hyperthermophilic archaeon
journal, October 2007
- Gerwe, Brian; Kelley, Laura-Lee Clancy; Dillard, Bret D.
- Journal of Structural and Functional Genomics, Vol. 8, Issue 1, p. 1-10
Purification and Properties of Acetyl-CoA Synthetase (ADP-forming), an Archaeal Enzyme of Acetate Formation and ATP Synthesis, from the Hyperthermophile Pyrococcus furiosus
journal, March 1997
- Glasemacher, Jurgen; Bock, Anne-Katrin; Schmid, Roland
- European Journal of Biochemistry, Vol. 244, Issue 2, p. 561-567
Microorganisms: Extremely Thermophilic
book, December 2009
- Gray, Steven R.; Adams, Michael W.W.; Kelly, Robert M.
- Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology
In vivo analyses of constitutive and regulated promoters in halophilic archaea
journal, January 2005
- Gregor, Dagmar; Pfeifer, Felicitas
- Microbiology, Vol. 151, Issue 1, p. 25-33
Phenotypic characterization of the archaebacterial genus Sulfolobus: comparison of five wild-type strains.
journal, December 1989
- Grogan, D. W.
- Journal of Bacteriology, Vol. 171, Issue 12, p. 6710-6719
The 1.75 Å Crystal Structure of Acetyl-CoA Synthetase Bound to Adenosine-5‘-propylphosphate and Coenzyme A †
journal, March 2003
- Gulick, Andrew M.; Starai, Vincent J.; Horswill, Alexander R.
- Biochemistry, Vol. 42, Issue 10, p. 2866-2873
Crystal Structure of 4-Chlorobenzoate:CoA Ligase/Synthetase in the Unliganded and Aryl Substrate-Bound States † , ‡
journal, July 2004
- Gulick, Andrew M.; Lu, Xuefeng; Dunaway-Mariano, Debra
- Biochemistry, Vol. 43, Issue 27, p. 8670-8679
Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase
journal, October 2009
- Gulick, Andrew M.
- ACS Chemical Biology, Vol. 4, Issue 10, p. 811-827
Pathways of Carbon Assimilation and Ammonia Oxidation Suggested by Environmental Genomic Analyses of Marine Crenarchaeota
journal, March 2006
- Hallam, Steven J.; Mincer, Tracy J.; Schleper, Christa
- PLoS Biology, Vol. 4, Issue 4, Article No. e95
Biooxidation capacity of the extremely thermoacidophilic archaeon Metallosphaera sedula under bioenergetic challenge
journal, June 1998
- Han, Chae J.; Kelly, Robert M.
- Biotechnology and Bioengineering, Vol. 58, Issue 6, p. 617-624
Enzymes, Extremely Thermophilic
book, April 2010
- Harris, James M.; Adams, Michael; Kelly, Robert M.
- Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology
Biological conversion of carbon dioxide and hydrogen into liquid fuels and industrial chemicals
journal, June 2013
- Hawkins, Aaron S.; McTernan, Patrick M.; Lian, Hong
- Current Opinion in Biotechnology, Vol. 24, Issue 3, p. 376-384
Autotrophic CO2 Fixation by Chloroflexus aurantiacus: Study of Glyoxylate Formation and Assimilation via the 3-Hydroxypropionate Cycle
journal, July 2001
- Herter, S.; Farfsing, J.; Gad'On, N.
- Journal of Bacteriology, Vol. 183, Issue 14, p. 4305-4316
Unusual ligand structure in Ni–Fe active center and an additional Mg site in hydrogenase revealed by high resolution X-ray structure analysis
journal, December 1997
- Higuchi, Yoshiki; Yagi, Tatsuhiko; Yasuoka, Noritake
- Structure, Vol. 5, Issue 12, p. 1671-1680
Homologous Expression of a Subcomplex of Pyrococcus furiosus Hydrogenase that Interacts with Pyruvate Ferredoxin Oxidoreductase
journal, October 2011
- Hopkins, R. Christopher; Sun, Junsong; Jenney, Francis E.
- PLoS ONE, Vol. 6, Issue 10, Article No.e26569
Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension
journal, April 1989
- Horton, Robert M.; Hunt, Henry D.; Ho, Steffan N.
- Gene, Vol. 77, Issue 1, p. 61-68
Metallosphaera sedula gen, and sp. nov. Represents a New Genus of Aerobic, Metal-Mobilizing, Thermoacidophilic Archaebacteria
journal, July 1989
- Huber, Gertrud; Spinnler, Carola; Gambacorta, Agata
- Systematic and Applied Microbiology, Vol. 12, Issue 1, p. 38-47
A dicarboxylate/4-hydroxybutyrate autotrophic carbon assimilation cycle in the hyperthermophilic Archaeum Ignicoccus hospitalis
journal, May 2008
- Huber, H.; Gallenberger, M.; Jahn, U.
- Proceedings of the National Academy of Sciences, Vol. 105, Issue 22, p. 7851-7856
Autotrophic CO2 fixation pathways in archaea (Crenarchaeota)
journal, February 2003
- Hügler, Michael; Huber, Harald; Stetter, Karl Otto
- Archives of Microbiology, Vol. 179, Issue 3, p. 160-173
Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula : Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation
journal, January 2003
- Hügler, Michael; Krieger, Robert S.; Jahn, Martina
- European Journal of Biochemistry, Vol. 270, Issue 4, p. 736-744
Assaying for the 3‐Hydroxypropionate Cycle of Carbon Fixation
book, January 2005
- Hügler, Michael; Fuchs, Georg
- Methods in Enzymology, Vol. 397, p. 212-221
AMP-forming acetyl-CoA synthetases in Archaea show unexpected diversity in substrate utilization
journal, January 2006
- Ingram-Smith, Cheryl; Smith, Kerry S.
- Archaea, Vol. 2, Issue 2, p. 95-107
Characterization of the Acyl Substrate Binding Pocket of Acetyl-CoA Synthetase
journal, September 2006
- Ingram-Smith, Cheryl; Woods, Barrett I.; Smith, Kerry S.
- Biochemistry, Vol. 45, Issue 38, p. 11482-11490
High-throughput production of Pyrococcus furiosus proteins: considerations for metalloproteins
journal, December 2004
- Jenney, F. E.; Brereton, P. S.; Izumi, M.
- Journal of Synchrotron Radiation, Vol. 12, Issue 1, p. 8-12
Crystal Structure of Yeast Acetyl-Coenzyme A Synthetase in Complex with AMP
journal, February 2004
- Jogl, Gerwald; Tong, Liang
- Biochemistry, Vol. 43, Issue 6, p. 1425-1431
Functional genomics-based studies of the microbial ecology of hyperthermophilic micro-organisms
journal, April 2004
- Johnson, M.R.; Montero, C.I.; Conners, S.B.
- Biochemical Society Transactions, Vol. 32, Issue 2, p. 188-192
Production of isopropanol by metabolically engineered Escherichia coli
journal, November 2007
- Jojima, Toru; Inui, Masayuki; Yukawa, Hideaki
- Applied Microbiology and Biotechnology, Vol. 77, Issue 6, p. 1219-1224
Probing the stability of native and activated forms of α2-macroglobulin
journal, January 2008
- Kaczowka, Steven J.; Madding, Lara S.; Epting, Kevin L.
- International Journal of Biological Macromolecules, Vol. 42, Issue 1, p. 62-67
Identification of the Phr-dependent heat shock regulon in the hyperthermophilic archaeon, Thermococcus kodakaraensis
journal, November 2009
- Kanai, Tamotsu; Takedomi, Shogo; Fujiwara, Shinsuke
- The Journal of Biochemistry, Vol. 147, Issue 3, p. 361-370
Exploiting microbial hyperthermophilicity to produce an industrial chemical, using hydrogen and carbon dioxide
journal, March 2013
- Keller, M. W.; Schut, G. J.; Lipscomb, G. L.
- Proceedings of the National Academy of Sciences, Vol. 110, Issue 15, p. 5840-5845
Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 Å resolution
journal, June 2007
- Clancy Kelley, Laura-Lee; Dillard, Bret D.; Tempel, Wolfram
- Acta Crystallographica Section F Structural Biology and Crystallization Communications, Vol. 63, Issue 7, p. 549-552
Electrochemical Potential-Step Investigations of the Aerobic Interconversions of [NiFe]-Hydrogenase from Allochromatium v inosum: Insights into the Puzzling Difference between Unready and Ready Oxidized Inactive States
journal, November 2004
- Lamle, Sophie E.; Albracht, Simon P. J.; Armstrong, Fraser A.
- Journal of the American Chemical Society, Vol. 126, Issue 45, p. 14899-14909
Membrane-bound hydrogenase and sulfur reductase of the hyperthermophilic and acidophilic archaeon Acidianus ambivalens
journal, September 2003
- Laska, Simone; Lottspeich, Friedrich; Kletzin, Arnulf
- Microbiology, Vol. 149, Issue 9, p. 2357-2371
Fermentative butanol production by clostridia
journal, October 2008
- Lee, Sang Yup; Park, Jin Hwan; Jang, Seh Hee
- Biotechnology and Bioengineering, Vol. 101, Issue 2, p. 209-228
Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels
journal, December 2008
- Lee, Sung Kuk; Chou, Howard; Ham, Timothy S.
- Current Opinion in Biotechnology, Vol. 19, Issue 6, p. 556-563
Requirements for Heterologous Production of a Complex Metalloenzyme: the Membrane-Bound [NiFe] Hydrogenase
journal, September 2005
- Lenz, O.; Gleiche, A.; Strack, A.
- Journal of Bacteriology, Vol. 187, Issue 18, p. 6590-6595
Natural Competence in the Hyperthermophilic Archaeon Pyrococcus furiosus Facilitates Genetic Manipulation: Construction of Markerless Deletions of Genes Encoding the Two Cytoplasmic Hydrogenases
journal, February 2011
- Lipscomb, Gina L.; Stirrett, Karen; Schut, Gerrit J.
- Applied and Environmental Microbiology, Vol. 77, Issue 7, p. 2232-2238
SurR: a transcriptional activator and repressor controlling hydrogen and elemental sulphur metabolism in Pyrococcus furiosus
journal, January 2009
- Lipscomb, Gina L.; Keese, Annette M.; Cowart, Darin M.
- Molecular Microbiology, Vol. 71, Issue 2, p. 332-349
The United States Department of Energy's Regional Carbon Sequestration Partnerships Program Validation Phase
journal, January 2008
- Litynski, John T.; Plasynski, Sean; McIlvried, Howard G.
- Environment International, Vol. 34, Issue 1, p. 127-138
Construction of a Shuttle Vector for, and Spheroplast Transformation of, the Hyperthermophilic Archaeon Pyrococcus abyssi
journal, November 2002
- Lucas, S.; Toffin, L.; Zivanovic, Y.
- Applied and Environmental Microbiology, Vol. 68, Issue 11, p. 5528-5536
Control of the Heterogeneous Azeotropic n -Butanol/Water Distillation System
journal, November 2008
- Luyben, William L.
- Energy & Fuels, Vol. 22, Issue 6, p. 4249-4258
[18] Hydrogenases I and II from Pyrococcus furiosus
book, January 2001
- Ma, Kesen; Adams, Michael W.W.
- Methods in Enzymology, Vol. 331, p. 208-216
Sulfide dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus: a new multifunctional enzyme involved in the reduction of elemental sulfur
journal, November 1994
- Ma, K.; Adams, M. W.
- Journal of Bacteriology, Vol. 176, Issue 21, p. 6509-6517
Rheological Properties of Guar Galactomannan Solutions during Hydrolysis with Galactomannanase and α-Galactosidase Enzyme Mixtures
journal, March 2007
- Mahammad, Shamsheer; Comfort, Donald A.; Kelly, Robert M.
- Biomacromolecules, Vol. 8, Issue 3, p. 949-956
Crystal structure of 4-hydroxybutyryl-CoA dehydratase: Radical catalysis involving a [4Fe-4S] cluster and flavin
journal, October 2004
- Martins, B. M.; Dobbek, H.; Cinkaya, I.
- Proceedings of the National Academy of Sciences, Vol. 101, Issue 44, p. 15645-15649
Disruption of a Sugar Transporter Gene Cluster in a Hyperthermophilic Archaeon Using a Host-Marker System Based on Antibiotic Resistance
journal, January 2007
- Matsumi, R.; Manabe, K.; Fukui, T.
- Journal of Bacteriology, Vol. 189, Issue 7, p. 2683-2691
Isoprenoid biosynthesis in Archaea – Biochemical and evolutionary implications
journal, January 2011
- Matsumi, Rie; Atomi, Haruyuki; Driessen, Arnold J. M.
- Research in Microbiology, Vol. 162, Issue 1, p. 39-52
Isoprenoid biosynthesis in Archaea – Biochemical and evolutionary implications
journal, January 2011
- Matsumi, Rie; Atomi, Haruyuki; Driessen, Arnold J. M.
- Research in Microbiology, Vol. 162, Issue 1, p. 39-52
Ethanol production from xylose in engineered Saccharomyces cerevisiae strains: current state and perspectives
journal, July 2009
- Matsushika, Akinori; Inoue, Hiroyuki; Kodaki, Tsutomu
- Applied Microbiology and Biotechnology, Vol. 84, Issue 1, p. 37-53
Structure determination of a new protein from backbone-centered NMR data and NMR-assisted structure prediction
journal, August 2006
- Mayer, K. L.; Qu, Y.; Bansal, S.
- Proteins: Structure, Function, and Bioinformatics, Vol. 65, Issue 2, p. 480-489
[FeFe] hydrogenases and their evolution: a genomic perspective
journal, March 2007
- Meyer, J.
- Cellular and Molecular Life Sciences, Vol. 64, Issue 9, p. 1063-1084
High-performance liquid chromatographic determination of mono-, poly- and hydroxycarboxylic acids in foods and beverages as their 2-nitrophenylhydrazides
journal, June 2000
- Miwa, Hiroshi
- Journal of Chromatography A, Vol. 881, Issue 1-2, p. 365-385
Colocation of Genes Encoding a tRNA-mRNA Hybrid and a Putative Signaling Peptide on Complementary Strands in the Genome of the Hyperthermophilic Bacterium Thermotoga maritima
journal, October 2006
- Montero, C. I.; Lewis, D. L.; Johnson, M. R.
- Journal of Bacteriology, Vol. 188, Issue 19, p. 6802-6807
Responses of Wild-Type and Resistant Strains of the Hyperthermophilic Bacterium Thermotoga maritima to Chloramphenicol Challenge
journal, June 2007
- Montero, Clemente I.; Johnson, Matthew R.; Chou, Chung-Jung
- Applied and Environmental Microbiology, Vol. 73, Issue 15, p. 5058-5065
4-Hydroxybutyryl-CoA Dehydratase from Clostridium aminobutyricum: Characterization of FAD and Iron−Sulfur Clusters Involved in an Overall Non-Redox Reaction
journal, September 1996
- Müh, Ute; Çinkaya, Irfan; Albracht, Simon P. J.
- Biochemistry, Vol. 35, Issue 36, p. 11710-11718
Engineering alternative butanol production platforms in heterologous bacteria
journal, July 2009
- Nielsen, David R.; Leonard, Effendi; Yoon, Sang-Hwal
- Metabolic Engineering, Vol. 11, Issue 4-5, p. 262-273
Recent progress in consolidated bioprocessing
journal, June 2012
- Olson, Daniel G.; McBride, John E.; Joe Shaw, A.
- Current Opinion in Biotechnology, Vol. 23, Issue 3, p. 396-405
Extremely thermostable L(+)-lactate dehydrogenase from thermotoga maritima: Cloning, characterization, and crystallization of the recombinant enzyme in its tetrameric and octameric state
journal, May 1996
- Ostendorp, Ralf; Auerbach, Günter; Jaenicke, Rainer
- Protein Science, Vol. 5, Issue 5, p. 862-873
Assessment of Options for Selective 1-Butanol Recovery from Aqueous Solution
journal, August 2009
- Oudshoorn, Arjan; van der Wielen, Luuk A. M.; Straathof, Adrie J. J.
- Industrial & Engineering Chemistry Research, Vol. 48, Issue 15, p. 7325-7336
High level heterologous expression in E.coli using the anaerobically-activated nirB promoter
journal, January 1991
- Oxer, M.D.; Bentley, C.M.; Doyle, J.G.
- Nucleic Acids Research, Vol. 19, Issue 11, p. 2889-2892
Bioenergetics of the metal/sulfur-oxidizing extreme thermoacidophile, Metallosphaera sedula
journal, December 1993
- Peeples, T. L.; Kelly, R. M.
- Fuel, Vol. 72, Issue 12, p. 1619-1624
Advanced biofuel production in microbes
journal, January 2010
- Peralta-Yahya, Pamela P.; Keasling, Jay D.
- Biotechnology Journal, Vol. 5, Issue 2, p. 147-162
Regulation of phosphate acquisition in Saccharomyces cerevisiae
journal, July 2003
- Persson, Bengt L.; Lagerstedt, Jens O.; Pratt, James R.
- Current Genetics, Vol. 43, Issue 4, p. 225-244
Expression of a functional NAD-reducing [NiFe] hydrogenase from the gram-positive Rhodococcus opacus in the gram-negative Ralstonia eutropha
journal, November 2001
- Porthun, Antje; Bernhard, Michael; Friedrich, Bärbel
- Archives of Microbiology, Vol. 177, Issue 2, p. 159-166
Structure-function relationships among the nickel-containing hydrogenases
journal, February 1992
- Przybyla, Alan E.; Robbins, Jeffery; Menon, Nanda
- FEMS Microbiology Letters, Vol. 88, Issue 2, p. 109-136
Aflatoxin conducive and non-conducive growth conditions reveal new gene associations with aflatoxin production
journal, June 2005
- Price, Michael S.; Conners, Shannon B.; Tachdjian, Sabrina
- Fungal Genetics and Biology, Vol. 42, Issue 6, p. 506-518
The microbiology of butyrate formation in the human colon
journal, December 2002
- Pryde, Susan E.; Duncan, Sylvia H.; Hold, Georgina L.
- FEMS Microbiology Letters, Vol. 217, Issue 2, p. 133-139
Transcriptional analysis of dynamic heat-shock response by the hyperthermophilic bacterium Thermotoga maritima
journal, February 2004
- Pysz, Marybeth A.; Ward, Donald E.; Shockley, Keith R.
- Extremophiles, Vol. 8, Issue 3, p. 209-217
Enzymology of the Acetyl-CoA Pathway of CO2 Fixation
journal, January 1991
- Ragsdale, Stephen W.
- Critical Reviews in Biochemistry and Molecular Biology, Vol. 26, Issue 3-4, p. 261-300
Identification of Missing Genes and Enzymes for Autotrophic Carbon Fixation in Crenarchaeota
journal, December 2010
- Ramos-Vera, W. H.; Weiss, M.; Strittmatter, E.
- Journal of Bacteriology, Vol. 193, Issue 5, p. 1201-1211
Copper tolerance of the thermoacidophilic archaeon Sulfolobus metallicus: possible role of polyphosphate metabolism
journal, January 2006
- Remonsellez, Francisco; Orell, Alvaro Orell; Jerez, Carlos A. Jerez
- Microbiology, Vol. 152, Issue 1, p. 59-66
The reductive acetyl coenzyme A pathway: sequence and heterologous expression of active methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase from Clostridium thermoaceticum
journal, October 1994
- Roberts, D. L.; Zhao, S.; Doukov, T.
- Journal of Bacteriology, Vol. 176, Issue 19, p. 6127-6130
Polarity in Archaeal Operon Transcription in Thermococcus kodakaraensis
journal, January 2008
- Santangelo, T. J.; Cubonova, L.; Matsumi, R.
- Journal of Bacteriology, Vol. 190, Issue 6, p. 2244-2248
A simple energy-conserving system: Proton reduction coupled to proton translocation
journal, June 2003
- Sapra, R.; Bagramyan, K.; Adams, M. W. W.
- Proceedings of the National Academy of Sciences, Vol. 100, Issue 13, p. 7545-7550
Thermostable ATP regeneration system using polyphosphate kinase from Thermosynechococcus elongatus BP-1 for d-amino acid dipeptide synthesis
journal, February 2007
- Sato, Masaru; Masuda, Yusuke; Kirimura, Kohtaro
- Journal of Bioscience and Bioengineering, Vol. 103, Issue 2, p. 179-184
Purification and properties of an iron-sulfur and FAD-containing 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ3-Δ2-isomerase from Clostridium aminobutyricum
journal, July 1993
- Scherf, Uwe; Buckel, Wolfgang
- European Journal of Biochemistry, Vol. 215, Issue 2, p. 421-429
Insights into the Metabolism of Elemental Sulfur by the Hyperthermophilic Archaeon Pyrococcus furiosus: Characterization of a Coenzyme A- Dependent NAD(P)H Sulfur Oxidoreductase
journal, April 2007
- Schut, G. J.; Bridger, S. L.; Adams, M. W. W.
- Journal of Bacteriology, Vol. 189, Issue 12, p. 4431-4441
The complete genome of the crenarchaeon Sulfolobus solfataricus P2
journal, June 2001
- She, Q.; Singh, R. K.; Confalonieri, F.
- Proceedings of the National Academy of Sciences, Vol. 98, Issue 14, p. 7835-7840
Driving Forces Enable High-Titer Anaerobic 1-Butanol Synthesis in Escherichia coli
journal, March 2011
- Shen, Claire R.; Lan, Ethan I.; Dekishima, Yasumasa
- Applied and Environmental Microbiology, Vol. 77, Issue 9, p. 2905-2915
Genome-Wide Transcriptional Variation within and between Steady States for Continuous Growth of the Hyperthermophile Thermotoga Maritima
journal, September 2005
- Shockley, K. R.; Scott, K. L.; Pysz, M. A.
- Applied and Environmental Microbiology, Vol. 71, Issue 9, p. 5572-5576
Carbon Dioxide-Fixation in Photosynthetic Green Sulfur Bacteria
journal, July 1970
- Sirevag, Reudun; Ormerod, J. G.
- Science, Vol. 169, Issue 3941, p. 186-188
Feedstocks for Lignocellulosic Biofuels
journal, August 2010
- Somerville, Cris; Youngs, Heather; Taylor, Caroline
- Science, Vol. 329, Issue 5993, p. 790-792
From The Cover: Hydrogen and bioenergetics in the Yellowstone geothermal ecosystem
journal, January 2005
- Spear, J. R.; Walker, J. J.; McCollom, T. M.
- Proceedings of the National Academy of Sciences, Vol. 102, Issue 7, p. 2555-2560
Sir2-Dependent Activation of Acetyl-CoA Synthetase by Deacetylation of Active Lysine
journal, December 2002
- Starai, V. J.; Celic, I.; Cole, R. N.
- Science, Vol. 298, Issue 5602, p. 2390-2392
Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol
journal, January 2008
- Steen, Eric J.; Chan, Rossana; Prasad, Nilu
- Microbial Cell Factories, Vol. 7, Issue 1, Article No. 36
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass
journal, January 2010
- Steen, Eric J.; Kang, Yisheng; Bokinsky, Gregory
- Nature, Vol. 463, Issue 7280, p. 559-562
13C-NMR study of autotrophic CO2 fixation pathways in the sulfur-reducing Archaebacterium Thermoproteus neutrophilus and in the phototrophic Eubacterium Chloroflexus aurantiacus
journal, April 1992
- Strauss, Gerhard; Eisenreich, Wolfgang; Bacher, Adelbert
- European Journal of Biochemistry, Vol. 205, Issue 2, p. 853-866
Enzymes of a novel autotrophic CO2 fixation pathway in the phototrophic bacterium Chloroflexus aurantiacus, the 3-hydroxypropionate cycle
journal, August 1993
- Strauss, Gerhard; Fuchs, Georg
- European Journal of Biochemistry, Vol. 215, Issue 3, p. 633-643
Protein production by auto-induction in high-density shaking cultures
journal, May 2005
- Studier, F. William
- Protein Expression and Purification, Vol. 41, Issue 1, p. 207-234
Comparison of Small- and Large-scale Expression of Selected Pyrococcus furiosus Genes as an Aid to High-throughput Protein Production
journal, September 2005
- Sugar, Frank J.; Jenney, Francis E.; Poole, Farris L.
- Journal of Structural and Functional Genomics, Vol. 6, Issue 2-3, p. 149-158
Heterologous Expression and Maturation of an NADP-Dependent [NiFe]-Hydrogenase: A Key Enzyme in Biofuel Production
journal, May 2010
- Sun, Junsong; Hopkins, Robert C.; Jenney, Francis E.
- PLoS ONE, Vol. 5, Issue 5, Article No. e10526
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences
journal, May 1999
- Tatusova, Tatiana A.; Madden, Thomas L.
- FEMS Microbiology Letters, Vol. 174, Issue 2, p. 247-250
Thermophilic ethanologenesis: future prospects for second-generation bioethanol production
journal, July 2009
- Taylor, Mark P.; Eley, Kirsten L.; Martin, Steve
- Trends in Biotechnology, Vol. 27, Issue 7, p. 398-405
3-Hydroxypropionyl-Coenzyme A Dehydratase and Acryloyl-Coenzyme A Reductase, Enzymes of the Autotrophic 3-Hydroxypropionate/4-Hydroxybutyrate Cycle in the Sulfolobales
journal, May 2009
- Teufel, R.; Kung, J. W.; Kockelkorn, D.
- Journal of Bacteriology, Vol. 191, Issue 14, p. 4572-4581
A sterilisation Time–Temperature Integrator based on amylase from the hyperthermophilic organism Pyrococcus furiosus
journal, March 2007
- Tucker, G. S.; Brown, H. M.; Fryer, P. J.
- Innovative Food Science & Emerging Technologies, Vol. 8, Issue 1, p. 63-72
Backbone solution structures of proteins using residual dipolar couplings: Application to a novel structural genomics target
journal, January 2005
- Valafar, H.; Mayer, K. L.; Bougault, C. M.
- Journal of Structural and Functional Genomics, Vol. 5, Issue 4, p. 241-254
Metabolic Pathway for Biosynthesis of Poly (3-Hydroxybutyrate-co-4-Hydroxybutyrate) from 4-Hydroxybutyrate by Alcaligenes eutrophus
journal, January 1995
- Valentin, Henry E.; Zwingmann, Gundula; Schonebaum, Andreas
- European Journal of Biochemistry, Vol. 227, Issue 1-2, p. 43-60
Hydrogenomics of the Extremely Thermophilic Bacterium Caldicellulosiruptor saccharolyticus
journal, September 2008
- van de Werken, H. J. G.; Verhaart, M. R. A.; VanFossen, A. L.
- Applied and Environmental Microbiology, Vol. 74, Issue 21, p. 6720-6729
Stable carbon isotope fractionations of the hyperthermophilic crenarchaeon Metallosphaera sedula
journal, March 2001
- Meer, Marcel T. J.; Schouten, Stefan; Rijpstra, W. Irene C.
- FEMS Microbiology Letters, Vol. 196, Issue 1, p. 67-70
Heterologous expression and properties of the γ-subunit of the Fe-only hydrogenase from Thermotoga maritima
journal, June 2001
- Verhagen, Marc F.J.M.; O’Rourke, Thomas W.; Menon, Angeli Lal
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1505, Issue 2-3, p. 209-219
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
journal, October 2007
- Vignais, Paulette M.; Billoud, Bernard
- Chemical Reviews, Vol. 107, Issue 10, p. 4206-4272
Classification and phylogeny of hydrogenases
journal, August 2001
- Vignais, Paulette M.; Billoud, Bernard; Meyer, Jacques
- FEMS Microbiology Reviews, Vol. 25, Issue 4, p. 455-501
Novel metal sites in protein structures
journal, December 1996
- Volbeda, Anne; Fontecilla-Camps, Juan Carlos; Frey, Michel
- Current Opinion in Structural Biology, Vol. 6, Issue 6, p. 804-812
Engineering microbes to produce biofuels
journal, June 2011
- Wackett, Lawrence P.
- Current Opinion in Biotechnology, Vol. 22, Issue 3, p. 388-393
PF0610, a Novel Winged Helix−Turn−Helix Variant Possessing a Rubredoxin-like Zn Ribbon Motif from the Hyperthermophilic Archaeon, Pyrococcus furiosus
journal, December 2006
- Wang, Xu; Lee, Han-Seung; Sugar, Frank J.
- Biochemistry, Vol. 46, Issue 3, p. 752-761
Comprehensive Study of the Hydration and Dehydration Reactions of Carbon Dioxide in Aqueous Solution
journal, December 2009
- Wang, Xiaoguang; Conway, William; Burns, Robert
- The Journal of Physical Chemistry A, Vol. 114, Issue 4, p. 1734-1740
Protein Production and Crystallization at SECSG – An Overview
journal, September 2005
- Wang, Bi-Cheng; Adams, Michael W.W.; Dailey, Harry
- Journal of Structural and Functional Genomics, Vol. 6, Issue 2-3, p. 233-243
Cold Shock of a Hyperthermophilic Archaeon: Pyrococcus furiosus Exhibits Multiple Responses to a Suboptimal Growth Temperature with a Key Role for Membrane-Bound Glycoproteins
journal, January 2005
- Weinberg, M. V.; Schut, G. J.; Brehm, S.
- Journal of Bacteriology, Vol. 187, Issue 1, p. 336-348
Low-pressure solubility of gases in liquid water
journal, April 1977
- Wilhelm, Emmerich.; Battino, Rubin.; Wilcock, Robert J.
- Chemical Reviews, Vol. 77, Issue 2, p. 219-262
In vitro hydrogen production by glucose dehydrogenase and hydrogenase
journal, July 1996
- Woodward, Jonathan; Mattingly, Susan M.; Danson, Michael
- Nature Biotechnology, Vol. 14, Issue 7, p. 872-874
Perspectives and new directions for the production of bioethanol using consolidated bioprocessing of lignocellulose
journal, June 2009
- Xu, Qi; Singh, Arjun; Himmel, Michael E.
- Current Opinion in Biotechnology, Vol. 20, Issue 3, p. 364-371
Spontaneous High-Yield Production of Hydrogen from Cellulosic Materials and Water Catalyzed by Enzyme Cocktails
journal, February 2009
- Ye, Xinhao; Wang, Yiran; Hopkins, Robert C.
- ChemSusChem, Vol. 2, Issue 2, p. 149-152
Molecular characterization of the recombinant iron-containing alcohol dehydrogenase from the hyperthermophilic Archaeon, Thermococcus strain ES1
journal, December 2008
- Ying, Xiangxian; Grunden, Amy M.; Nie, Lin
- Extremophiles, Vol. 13, Issue 2, p. 299-311
Parallel evolution of transcriptome architecture during genome reorganization
journal, July 2011
- Yoon, S. H.; Reiss, D. J.; Bare, J. C.
- Genome Research, Vol. 21, Issue 11, p. 1892-1904
Microwave Activation of Enzymatic Catalysis
journal, August 2008
- Young, Douglas D.; Nichols, Jason; Kelly, Robert M.
- Journal of the American Chemical Society, Vol. 130, Issue 31, p. 10048-10049
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus
journal, December 2009
- Zarzycki, Jan; Brecht, Volker; Müller, Michael
- Proceedings of the National Academy of Sciences, Vol. 106, Issue 50, p. 21317-21322
High-Yield Hydrogen Production from Starch and Water by a Synthetic Enzymatic Pathway
journal, May 2007
- Zhang, Y.-H. Percival; Evans, Barbara R.; Mielenz, Jonathan R.
- PLoS ONE, Vol. 2, Issue 5, Article No. e456
A Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutant derivative highly active and stereoselective on phenylacetone and benzylacetone
journal, January 2007
- Ziegelmann-Fjeld, Karla I.; Musa, Musa M.; Phillips, Robert S.
- Protein Engineering, Design and Selection, Vol. 20, Issue 2, p. 47-55