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Title: Radioisotope trithiol complexes

The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of radioisotopes present in low concentrations. In certain embodiments, the complex contains a linking domain configured to conjugate the radioisotope trithiol complex to a targeting vector. The invention is also directed to a novel method of linking the radioisotope to a trithiol compound to form the radioisotope trithiol complex. The inventive radioisotope trithiol complexes may be utilized for a variety of applications, including diagnostics and/or treatment in nuclear medicine.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1344768
Assignee:
THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, MO) CHO
Patent Number(s):
9,427,483
Application Number:
14/679,520
Contract Number:
SC0003851
Resource Relation:
Patent File Date: 2015 Apr 06
Research Org:
THE CURATORS OF THE UNIVERSITY OF MISSOURI, Columbia, MO (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE

Other works cited in this record:

A new method for radiochemical separation of arsenic from irradiated germanium oxide
journal, September 2005

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