Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same

Liu, Chang-Jun; Cai, Yuanheng

Title: Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same

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Abstract

Specialized (iso)eugenol 4-O-methyltransferase (s-IEMT) enzymes having increased capacity for methylation of monolignols are disclosed. The s-IEMTs have unique activity favoring methylation of coniferyl alcohol versus sinapyl alcohol. Various s-IEMTs methylate ferulic acid. Means for producing the various s-IEMTs are provided. The s-IEMTs are useful for modification of lignin content and production of aromatic compounds.

Inventors:: Liu, Chang-Jun; Cai, Yuanheng

Issue Date:: 2017-01-31

Research Org.:: Brookhaven National Lab. (BNL), Upton, NY (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1342100

Patent Number(s):: 9556420

Application Number:: 14/306,511

Assignee:: Brookhaven Science Associates, LLC

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N9/1007 - {Methyltransferases

C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
C12Y201/01146 -

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N15/8255 - {involving lignin biosynthesis}

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DOE Contract Number:: AC02-98CH10886

Resource Type:: Patent

Resource Relation:: Patent File Date: 2014 Jun 17

Country of Publication:: United States

Language:: English

Subject:: 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats


                    Liu, Chang-Jun, and Cai, Yuanheng. Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same.  United States: N. p., 2017. 
        Web.

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                    Liu, Chang-Jun, & Cai, Yuanheng. Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same.  United States.

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                    Liu, Chang-Jun, and Cai, Yuanheng. Tue .  
        "Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same".  United States.  https://www.osti.gov/servlets/purl/1342100.

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@article{osti_1342100,

  title        = {Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same},

  author       = {Liu, Chang-Jun and Cai, Yuanheng},

  abstractNote = {Specialized (iso)eugenol 4-O-methyltransferase (s-IEMT) enzymes having increased capacity for methylation of monolignols are disclosed. The s-IEMTs have unique activity favoring methylation of coniferyl alcohol versus sinapyl alcohol. Various s-IEMTs methylate ferulic acid. Means for producing the various s-IEMTs are provided. The s-IEMTs are useful for modification of lignin content and production of aromatic compounds.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2017},

  month        = {1}

}

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