Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same

Title: Specialized (iso)eugenol-4-O-methyltransferases (s-IEMTs) and methods of making and using the same

Specialized (iso)eugenol 4-O-methyltransferase (s-IEMT) enzymes having increased capacity for methylation of monolignols are disclosed. The s-IEMTs have unique activity favoring methylation of coniferyl alcohol versus sinapyl alcohol. Various s-IEMTs methylate ferulic acid. Means for producing the various s-IEMTs are provided. The s-IEMTs are useful for modification of lignin content and production of aromatic compounds.

Inventors:: Liu, Chang-Jun; Cai, Yuanheng

Issue Date:: 2017-01-31

OSTI Identifier:: 1342100

Assignee:: Brookhaven Science Associates, LLC BNL

Patent Number(s):: 9,556,420

Application Number:: 14/306,511

Contract Number:: AC02-98CH10886

Resource Relation:: Patent File Date: 2014 Jun 17

Research Org:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Org:: USDOE

Country of Publication:: United States

Language:: English

Subject:: 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

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Works referenced in this record:

Methods for simultaneous control of lignin content and composition, and cellulose content in plants
patent, April 2009

Chiang, Vincent; Li, Laigeng
US Patent Document 7,514,596
URL: http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/7514596

Monolignol 4-O-methyltransferases and uses thereof
patent, November 2014

Liu, Chang-Jun; Bhuiya, Mohammad-Wadud; Zhang, Kewei
US Patent Document 8,889,392
URL: http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/8889392

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