Bacterial production of methyl ketones
Abstract
The present invention relates to methods and compositions for increasing production of methyl ketones in a genetically modified host cell that overproduces .beta.-ketoacyl-CoAs through a re-engineered .beta.-oxidation pathway and overexpresses FadM.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1342098
- Patent Number(s):
- 9556458
- Application Number:
- 14/354,510
- Assignee:
- The Regents of the University of California
- Patent Classifications (CPCs):
-
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02P - CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2012 Oct 26
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Beller, Harry R., and Goh, Ee-Been. Bacterial production of methyl ketones. United States: N. p., 2017.
Web.
Beller, Harry R., & Goh, Ee-Been. Bacterial production of methyl ketones. United States.
Beller, Harry R., and Goh, Ee-Been. Tue .
"Bacterial production of methyl ketones". United States. https://www.osti.gov/servlets/purl/1342098.
@article{osti_1342098,
title = {Bacterial production of methyl ketones},
author = {Beller, Harry R. and Goh, Ee-Been},
abstractNote = {The present invention relates to methods and compositions for increasing production of methyl ketones in a genetically modified host cell that overproduces .beta.-ketoacyl-CoAs through a re-engineered .beta.-oxidation pathway and overexpresses FadM.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {1}
}
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Works referenced in this record:
Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals
journal, August 2011
- Dellomonaco, Clementina; Clomburg, James M.; Miller, Elliot N.
- Nature, Vol. 476, Issue 7360, p. 355-359
Synthesis of methyl ketones by metabolically engineered Escherichia coli
journal, August 2012
- Park, John; Rodríguez-Moyá, María; Li, Mai
- Journal of Industrial Microbiology & Biotechnology, Vol. 39, Issue 11, p. 1703-1712