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Title: Ion focusing

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1339553
Assignee:
Purdue Research Foundation (West Lafayette, IN) CHO
Patent Number(s):
9,548,192
Application Number:
14/936,223
Contract Number:
FG02-06ER15807
Resource Relation:
Patent File Date: 2015 Nov 09
Research Org:
Purdue Research Foundation, West Lafayette, IN (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
70 PLASMA PHYSICS AND FUSION TECHNOLOGY

Other works cited in this record:

Apparatus and method for focusing ions and charged particles at atmospheric pressure
patent, June 2004

Laminated tube for the transport of charged particles contained in a gaseous medium
patent, September 2005

Method and apparatus for aerodynamic ion focusing
patent, January 2006

Method and system for desorption electrospray ionization
patent, February 2008

System and method for the preparation of arrays of biological or other molecules
patent, April 2008

Method and device for non-contact sampling and detection
patent, September 2009

Ion transport device and modes of operation thereof
patent, August 2010

Microengineered vacuum interface for an ionization system
patent, August 2010

Discontinuous atmospheric pressure interface
patent, November 2012

Apparatus and methods for analyzing ions
patent, January 2013

Systems and methods for transfer of ions for analysis
patent, April 2013

Ion focusing
patent, November 2015

Simulation of Ion Motion at Atmospheric Pressure: Particle Tracing Versus Electrokinetic Flow
journal, December 2011
  • Wissdorf, Walter; Pohler, Larissa; Klee, Sonja
  • Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 2, p. 397-406
  • DOI: 10.1007/s13361-011-0290-x

Growth of phenylene vinylene thin films via surface polymerization by ion-assisted deposition
journal, September 2008
  • Wroble, Amanda T.; Wildeman, Jurjen; Asunskis, Daniel J.
  • Thin Solid Films, Vol. 516, Issue 21, p. 7386-7392
  • DOI: 10.1016/j.tsf.2008.02.024

Inkjet-Printed Microfluidic Multianalyte Chemical Sensing Paper
journal, September 2008
  • Abe, Koji; Suzuki, Koji; Citterio, Daniel
  • Analytical Chemistry, Vol. 80, Issue 18, p. 6928-6934
  • DOI: 10.1021/ac800604v

Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations
journal, August 2012
  • Badu-Tawiah, Abraham K.; Li, Anyin; Jjunju, Fred P. M.
  • Angewandte Chemie International Edition, Vol. 51, Issue 37, p. 9417-9421
  • DOI: 10.1002/anie.201205044

Reactions of Microsolvated Organic Compounds at Ambient Surfaces: Droplet Velocity, Charge State, and Solvent Effects
journal, March 2012
  • Badu-Tawiah, Abraham K.; Campbell, Dahlia I.; Cooks, R. Graham
  • Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 6, p. 1077-1084
  • DOI: 10.1007/s13361-012-0365-3

Reactions of Organic Ions at Ambient Surfaces in a Solvent-Free Environment
journal, January 2012
  • Badu-Tawiah, Abraham K.; Cyriac, Jobin; Cooks, R. Graham
  • Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 5, p. 842-849
  • DOI: 10.1007/s13361-012-0337-7

Current status of droplet evaporation in turbulent flows
journal, July 2006

Low-Cost Printing of Poly(dimethylsiloxane) Barriers To Define Microchannels in Paper
journal, May 2008
  • Bruzewicz, Derek A.; Reches, Meital; Whitesides, George M.
  • Analytical Chemistry, Vol. 80, Issue 9, p. 3387-3392
  • DOI: 10.1021/ac702605a

Practical implications of some recent studies in electrospray ionization fundamentals
journal, January 2001
  • Cech, Nadja B.; Enke, Christie G.
  • Mass Spectrometry Reviews, Vol. 20, Issue 6, p. 362-387
  • DOI: 10.1002/mas.10008

Non-proximate detection of explosives and chemical warfare agent simulants by desorption electrospray ionization mass spectrometry
journal, June 2006
  • Cotte-Rodríguez, Ismael; Cooks, R. Graham
  • Chem. Commun., Issue 28, p. 2968-2970
  • DOI: 10.1039/B606020J

Low-Energy Ionic Collisions at Molecular Solids
journal, June 2012
  • Cyriac, Jobin; Pradeep, T.; Kang, H.
  • Chemical Reviews, Vol. 112, Issue 10, p. 5356-5411
  • DOI: 10.1021/cr200384k

Handheld Rectilinear Ion Trap Mass Spectrometer
journal, September 2006
  • Gao, Liang; Song, Qingyu; Patterson, Garth E.
  • Analytical Chemistry, Vol. 78, Issue 17, p. 5994-6002
  • DOI: 10.1021/ac061144k

Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry
journal, October 2009
  • Gao, Liang; Li, Guangtao; Cyriac, Jobin
  • The Journal of Physical Chemistry C, Vol. 114, Issue 12, p. 5331-5337
  • DOI: 10.1021/jp904960t

Gas-flow assisted ion transfer for mass spectrometry: Flow assisted ion transfer
journal, February 2012
  • Garimella, Sandilya; Xu, Wei; Huang, Guangming
  • Journal of Mass Spectrometry, Vol. 47, Issue 2, p. 201-207
  • DOI: 10.1002/jms.2955

The growth and modification of materials via ion–surface processing
journal, March 2002

Sampling Wand for an Ion Trap Mass Spectrometer
journal, March 2011
  • Hou, Keyong; Xu, Wei; Xu, Jian
  • Analytical Chemistry, Vol. 83, Issue 5, p. 1857-1861
  • DOI: 10.1021/ac102962e

Ambient Ionization Mass Spectrometry
journal, June 2010

Desorption electrospray ionization and other ambient ionization methods: current progress and preview
journal, March 2010
  • Ifa, Demian R.; Wu, Chunping; Ouyang, Zheng
  • The Analyst, Vol. 135, Issue 4, p. 669-681
  • DOI: 10.1039/B925257F

Vibrational Spectroscopy and Mass Spectrometry for Characterization of Soft Landed Polyatomic Molecules
journal, July 2011
  • Cyriac, Jobin; Li, Guangtao; Cooks, R. Graham
  • Analytical Chemistry, Vol. 83, Issue 13, p. 5114-5121
  • DOI: 10.1021/ac200118f

In situ Raman spectroscopy of surfaces modified by ion soft landing
journal, February 2012
  • Cyriac, Jobin; Wleklinski, Michael; Li, Guangtao
  • The Analyst, Vol. 137, Issue 6, p. 1363-1369
  • DOI: 10.1039/C2AN16163J

Nano-electrospray ionization mass spectrometry: addressing analytical problems beyond routine
journal, March 2000
  • Karas, M.; Bahr, U.; Dülcks, T.
  • Fresenius' Journal of Analytical Chemistry, Vol. 366, Issue 6-7, p. 669-676
  • DOI: 10.1007/s002160051561

The ion funnel: Theory, implementations, and applications
journal, April 2009
  • Kelly, Ryan T.; Tolmachev, Aleksey V.; Page, Jason S.
  • Mass Spectrometry Reviews, Vol. 29, Issue 2, p. 294-312
  • DOI: 10.1002/mas.20232

Dielectric-Barrier Discharges: Their History, Discharge Physics, and Industrial Applications
journal, March 2003
  • Kogelschatz, Ulrich
  • Plasma Chemistry and Plasma Processing, Vol. 23, Issue 1, p. 1-46
  • DOI: 10.1023/A:1022470901385

The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments
journal, September 2008
  • Lai, Hanh; McJunkin, Timothy R.; Miller, Carla J.
  • International Journal of Mass Spectrometry, Vol. 276, Issue 1, p. 1-8
  • DOI: 10.1016/j.ijms.2008.06.011

Paper-Based Microfluidic Devices by Plasma Treatment
journal, December 2008
  • Li, Xu; Tian, Junfei; Nguyen, Thanh
  • Analytical Chemistry, Vol. 80, Issue 23, p. 9131-9134
  • DOI: 10.1021/ac801729t

Molecular ion yield enhancement in static secondary ion mass spectrometry by soft landing of protonated water clusters
journal, February 2010
  • Li, Guangtao; Cyriac, Jobin; Gao, Liang
  • Surface and Interface Analysis, Vol. 43, Issue 1-2, p. 498-501
  • DOI: 10.1002/sia.3161

Chemistry of mass-selected Au clusters deposited on sputter-damaged HOPG surfaces: The unique properties of Au8 clusters
journal, May 2007
  • Lim, Dong Chan; Dietsche, Rainer; Bubek, Moritz
  • Chemical Physics Letters, Vol. 439, Issue 4-6, p. 364-368
  • DOI: 10.1016/j.cplett.2007.04.001

FLASH: A rapid method for prototyping paper-based microfluidic devices
journal, January 2008
  • Martinez, Andres W.; Phillips, Scott T.; Wiley, Benjamin J.
  • Lab on a Chip, Vol. 8, Issue 12, p. 2146-2150
  • DOI: 10.1039/B811135A

Three-dimensional microfluidic devices fabricated in layered paper and tape
journal, December 2008
  • Martinez, A. W.; Phillips, S. T.; Whitesides, G. M.
  • Proceedings of the National Academy of Sciences, Vol. 105, Issue 50, p. 19606-19611
  • DOI: 10.1073/pnas.0810903105

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays
journal, February 2007
  • Martinez, Andres W.; Phillips, Scott T.; Butte, Manish J.
  • Angewandte Chemie International Edition, Vol. 46, Issue 8, p. 1318-1320
  • DOI: 10.1002/anie.200603817

Direct monitoring of toxic compounds in air using a portable mass spectrometer
journal, February 2006
  • Mulligan, Christopher C.; Justes, Dina R.; Noll, Robert. J.
  • The Analyst, Vol. 131, Issue 4, p. 556-567
  • DOI: 10.1039/B517541K

Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface
journal, September 2007
  • Page, Jason S.; Kelly, Ryan T.; Tang, Keqi
  • Journal of the American Society for Mass Spectrometry, Vol. 18, Issue 9, p. 1582-1590
  • DOI: 10.1016/j.jasms.2007.05.018

Redox chemistry in thin layers of organometallic complexes prepared using ion soft landing
journal, November 2011
  • Peng, Wen-Ping; Johnson, Grant E.; Fortmeyer, Ivy C.
  • Phys. Chem. Chem. Phys., Vol. 13, Issue 1, p. 267-275
  • DOI: 10.1039/C0CP01457E

Simulation of Ion Motion in FAIMS through Combined Use of SIMION and Modified SDS
journal, November 2009
  • Prasad, Satendra; Tang, Keqi; Manura, David
  • Analytical Chemistry, Vol. 81, Issue 21, p. 8749-8757
  • DOI: 10.1021/ac900880v

Processing of giant graphene molecules by soft-landing mass spectrometry
journal, March 2006
  • Räder, Hans Joachim; Rouhanipour, Ali; Talarico, Anna Maria
  • Nature Materials, Vol. 5, Issue 4, p. 276-280
  • DOI: 10.1038/nmat1597

Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
journal, October 2004

Photoemission Studies of Polythiophene and Polyphenyl Films Produced via Surface Polymerization by Ion-Assisted Deposition
journal, April 2005
  • Tepavcevic, Sanja; Wroble, Amanda T.; Bissen, Mark
  • The Journal of Physical Chemistry B, Vol. 109, Issue 15, p. 7134-7140
  • DOI: 10.1021/jp0451445

Grafting Crown Ether Alkali Host−Guest Complexes at Surfaces by Electrospray Ion Beam Deposition
journal, September 2010
  • Thontasen, Nicha; Levita, Giacomo; Malinowski, Nikola
  • The Journal of Physical Chemistry C, Vol. 114, Issue 41, p. 17768-17772
  • DOI: 10.1021/jp106123q

Preparative Soft and Reactive Landing of Multiply Charged Protein Ions on a Plasma-Treated Metal Surface
journal, August 2005
  • Volný, Michael; Elam, W. Timothy; Branca, Andrew
  • Analytical Chemistry, Vol. 77, Issue 15, p. 4890-4896
  • DOI: 10.1021/ac0507136

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