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Title: Transgenic cells with increased plastoquinone levels and methods of use

Disclosed herein are transgenic cells expressing a heterologous nucleic acid encoding a prephenate dehydrogenase (PDH) protein, a heterologous nucleic acid encoding a homogentisate solanesyl transferase (HST) protein, a heterologous nucleic acid encoding a deoxyxylulose phosphate synthase (DXS) protein, or a combination of two or more thereof. In particular examples, the disclosed transgenic cells have increased plastoquinone levels. Also disclosed are methods of increasing cell growth rates or production of biomass by cultivating transgenic cells expressing a heterologous nucleic acid encoding a PDH protein, a heterologous nucleic acid encoding an HST protein, a heterologous nucleic acid encoding a DXS protein, or a combination of two or more thereof under conditions sufficient to produce cell growth or biomass.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1337682
Assignee:
LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, NM LANL
Patent Number(s):
9,528,119
Application Number:
14/307,180
Contract Number:
AC52-06NA25396
Resource Relation:
Patent File Date: 2014 Jun 17
Research Org:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Works referenced in this record:

Optimization of photosynthetic light energy utilization by microalgae
journal, October 2012