Rapid and highly fieldable viral diagnostic

McKnight, Timothy E.

Advanced Search OptionsAdvanced Search queries use a traditional Term Search. For more info, see our FAQ.

All Fields:

Patent Title:

Abstract:

Assignee:

Inventor(s):

Patent Number:

Patent Classification (CPC):

All Classifications
A - human necessities
A01 - agriculture
A21 - baking
A22 - butchering
A23 - foods or foodstuffs
A24 - tobacco
A41 - wearing apparel
A42 - headwear
A43 - footwear
A44 - haberdashery
A45 - hand or travelling articles
A46 - brushware
A47 - furniture
A61 - medical or veterinary science
A62 - life-saving
A63 - sports
A99 - subject matter not otherwise provided for in this section
B - performing operations
B01 - physical or chemical processes or apparatus in general
B02 - crushing, pulverising, or disintegrating
B03 - separation of solid materials using liquids or using pneumatic tables or jigs
B04 - centrifugal apparatus or machines for carrying-out physical or chemical processes
B05 - spraying or atomising in general
B06 - generating or transmitting mechanical vibrations in general
B07 - separating solids from solids
B08 - cleaning
B09 - disposal of solid waste
B21 - mechanical metal-working without essentially removing material
B22 - casting
B23 - machine tools
B24 - grinding
B25 - hand tools
B26 - hand cutting tools
B27 - working or preserving wood or similar material
B28 - working cement, clay, or stone
B29 - working of plastics
B30 - presses
B31 - making articles of paper, cardboard or material worked in a manner analogous to paper
B32 - layered products
B33 - additive manufacturing technology
B41 - printing
B42 - bookbinding
B43 - writing or drawing implements
B44 - decorative arts
B60 - vehicles in general
B61 - railways
B62 - land vehicles for travelling otherwise than on rails
B63 - ships or other waterborne vessels
B64 - aircraft
B65 - conveying
B66 - hoisting
B67 - opening, closing {or cleaning} bottles, jars or similar containers
B68 - saddlery
B81 - microstructural technology
B82 - nanotechnology
B99 - subject matter not otherwise provided for in this section
C - chemistry
C01 - inorganic chemistry
C02 - treatment of water, waste water, sewage, or sludge
C03 - glass
C04 - cements
C05 - fertilisers
C06 - explosives
C07 - organic chemistry
C08 - organic macromolecular compounds
C09 - dyes
C10 - petroleum, gas or coke industries
C11 - animal or vegetable oils, fats, fatty substances or waxes
C12 - biochemistry
C13 - sugar industry
C14 - skins
C21 - metallurgy of iron
C22 - metallurgy
C23 - coating metallic material
C25 - electrolytic or electrophoretic processes
C30 - crystal growth
C40 - combinatorial technology
C99 - subject matter not otherwise provided for in this section
D - textiles
D01 - natural or man-made threads or fibres
D02 - yarns
D03 - weaving
D04 - braiding
D05 - sewing
D06 - treatment of textiles or the like
D07 - ropes
D10 - indexing scheme associated with sublasses of section d, relating to textiles
D21 - paper-making
D99 - subject matter not otherwise provided for in this section
E - fixed constructions
E01 - construction of roads, railways, or bridges
E02 - hydraulic engineering
E03 - water supply
E04 - building
E05 - locks
E06 - doors, windows, shutters, or roller blinds in general
E21 - earth drilling
E99 - subject matter not otherwise provided for in this section
F - mechanical engineering
F01 - machines or engines in general
F02 - combustion engines
F03 - machines or engines for liquids
F04 - positive - displacement machines for liquids
F05 - indexing schemes relating to engines or pumps in various subclasses of classes f01-f04
F15 - fluid-pressure actuators
F16 - engineering elements and units
F17 - storing or distributing gases or liquids
F21 - lighting
F22 - steam generation
F23 - combustion apparatus
F24 - heating
F25 - refrigeration or cooling
F26 - drying
F27 - furnaces
F28 - heat exchange in general
F41 - weapons
F42 - ammunition
F99 - subject matter not otherwise provided for in this section
G - physics
G01 - measuring
G02 - optics
G03 - photography
G04 - horology
G05 - controlling
G06 - computing
G07 - checking-devices
G08 - signalling
G09 - education
G10 - musical instruments
G11 - information storage
G12 - instrument details
G16 - information and communication technology [ict] specially adapted for specific application fields
G21 - nuclear physics
G99 - subject matter not otherwise provided for in this section
H - electricity
H01 - basic electric elements
H02 - generation
H03 - basic electronic circuitry
H04 - electric communication technique
H05 - electric techniques not otherwise provided for
H99 - subject matter not otherwise provided for in this section
Y - new / cross sectional technologies
Y02 - technologies or applications for mitigation or adaptation against climate change
Y04 - information or communication technologies having an impact on other technology areas
Y10 - technical subjects covered by former uspc

More Options ...

Title: Rapid and highly fieldable viral diagnostic

Abstract

The present invention relates to a rapid, highly fieldable, nearly reagentless diagnostic to identify active RNA viral replication in a live, infected cells, and more particularly in leukocytes and tissue samples (including biopsies and nasal swabs) using an array of a plurality of vertically-aligned nanostructures that impale the cells and introduce a DNA reporter construct that is expressed and amplified in the presence of active viral replication.

Inventors:: McKnight, Timothy E.

Issue Date:: Tue Dec 20 00:00:00 EST 2016

Research Org.:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1336928

Patent Number(s):: 9523132

Application Number:: 14/212,718

Assignee:: UT-Battelle, LLC (Oak Ridge, TN)

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS

Show more

C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
C12Q1/701 - {Specific hybridization probes}

Show less

DOE Contract Number:: AC05-00OR22725

Resource Type:: Patent

Resource Relation:: Patent File Date: 2014 Mar 14

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES

Citation Formats


                    McKnight, Timothy E. Rapid and highly fieldable viral diagnostic.  United States: N. p., 2016. 
        Web.

Copy to clipboard


                    McKnight, Timothy E. Rapid and highly fieldable viral diagnostic.  United States.

Copy to clipboard


                    McKnight, Timothy E. Tue .  
        "Rapid and highly fieldable viral diagnostic".  United States.  https://www.osti.gov/servlets/purl/1336928.

Copy to clipboard


                    
@article{osti_1336928,

  title        = {Rapid and highly fieldable viral diagnostic},

  author       = {McKnight, Timothy E.},

  abstractNote = {The present invention relates to a rapid, highly fieldable, nearly reagentless diagnostic to identify active RNA viral replication in a live, infected cells, and more particularly in leukocytes and tissue samples (including biopsies and nasal swabs) using an array of a plurality of vertically-aligned nanostructures that impale the cells and introduce a DNA reporter construct that is expressed and amplified in the presence of active viral replication.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Dec 20 00:00:00 EST 2016},

  month        = {Tue Dec 20 00:00:00 EST 2016}

}

Copy to clipboard

Patent:

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Device for depletion of the leukocyte content of blood and blood components
patent, May 1990

Pall, David B.
US Patent Document 4,923,620
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4923620

Device and method for depletion of the leukocyte content of blood and blood components
patent, May 1990

Pall, David B.
US Patent Document 4,925,572
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4925572

Method and apparatus for sustaining viability of biological cells on a substrate
patent, December 2011

McKnight, Timothy E.; Melechko, Anatoli V.; Simpson, Michael L.
US Patent Document 8,076,124
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8076124

Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures
patent-application, October 2004

McKnight, Timothy E.; Melechko, Anatoli V.; Griffin, Guy D.
US Patent Application 10/408294; 20040197909
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20040197909

Tracking Gene Expression after DNA Delivery Using Spatially Indexed Nanofiber Arrays
journal, July 2004

McKnight, Timothy E.; Melechko, Anatoli V.; Hensley, Dale K.
Nano Letters, Vol. 4, Issue 7
https://doi.org/10.1021/nl049504b

Inducible RNA Interference-Mediated Gene Silencing Using Nanostructured Gene Delivery Arrays
journal, December 2007

Mann, David G. J.; McKnight, Timothy E.; McPherson, Jackson T.
ACS Nano, Vol. 2, Issue 1
https://doi.org/10.1021/nn700198y

Functional RNA Elements in the Dengue Virus Genome
journal, September 2011

Gebhard, Leopoldo G.; Filomatori, Claudia V.; Gamarnik, Andrea V.
Viruses, Vol. 3, Issue 9
https://doi.org/10.3390/v3091739

Development of Dengue type-2 virus replicons expressing GFP reporter gene in study of viral RNA replication
journal, February 2012

Leardkamolkarn, Vijittra; Sirigulpanit, Wipawan; Chotiwan, Nunya
Virus Research, Vol. 163, Issue 2, p. 552-562
https://doi.org/10.1016/j.virusres.2011.12.007

Identification of Cis -Acting Elements in the 3′-Untranslated Region of the Dengue Virus Type 2 RNA That Modulate Translation and Replication
journal, April 2011

Manzano, Mark; Reichert, Erin D.; Polo, Stephanie
Journal of Biological Chemistry, Vol. 286, Issue 25
https://doi.org/10.1074/jbc.M111.234302

Insights into dengue virus genome replication
journal, September 2010

Alcaraz-Estrada, Sofia Lizeth; Yocupicio-Monroy, Martha; del Angel, Rosa María
Future Virology, Vol. 5, Issue 5
https://doi.org/10.2217/fvl.10.49

cis- and trans-Acting Elements in Flavivirus RNA Replication
journal, April 2000

Khromykh, A. A.; Sedlak, P. L.; Westaway, E. G.
Journal of Virology, Vol. 74, Issue 7
https://doi.org/10.1128/JVI.74.7.3253-3263.2000

Hepatitis C virus replicons: dinosaurs still in business?
journal, January 2009

Woerz, I.; Lohmann, V.; Bartenschlager, R.
Journal of Viral Hepatitis, Vol. 16, Issue 1, p. 1-9
https://doi.org/10.1111/j.1365-2893.2008.01066.x

The Foot-and-Mouth Disease Virus cis-Acting Replication Element (cre) Can Be Complemented in trans within Infected Cells
journal, February 2003

Tiley, L.; King, A. M. Q.; Belsham, G. J.
Journal of Virology, Vol. 77, Issue 3
https://doi.org/10.1128/JVI.77.3.2243-2246.2003

Cis-active RNA elements (CREs) and picornavirus RNA replication
journal, February 2009

Steil, Benjamin P.; Barton, David J.
Virus Research, Vol. 139, Issue 2, p. 240-252
https://doi.org/10.1016/j.virusres.2008.07.027

Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine
journal, October 2007

Ljungberg, K.; Whitmore, A. C.; Fluet, M. E.
Journal of Virology, Vol. 81, Issue 24
https://doi.org/10.1128/JVI.01799-07

Novel Replicon-Based Reporter Gene Assay for Detection of Rubella Virus in Clinical Specimens
journal, February 2005

Tzeng, W. -P.; Zhou, Y.; Icenogle, J.
Journal of Clinical Microbiology, Vol. 43, Issue 2
https://doi.org/10.1128/JCM.43.2.879-885.2005

High-throughput assay using a GFP-expressing replicon for SARS-CoV drug discovery
journal, November 2008

Ge, F.; Xiong, S.; Lin, F.
Antiviral Research, Vol. 80, Issue 2
https://doi.org/10.1016/j.antiviral.2008.05.005

Bioluminescent bioreporter integrated circuits: potentially small, rugged and inexpensive whole-cell biosensors for remote environmental monitoring
journal, January 2004

Nivens, D. E.; McKnight, T. E.; Moser, S. A.
Journal of Applied Microbiology, Vol. 96, Issue 1
https://doi.org/10.1046/j.1365-2672.2003.02114.x

IFITM Proteins Restrict Antibody-Dependent Enhancement of Dengue Virus Infection
journal, March 2012

Chan, Ying Kai; Huang, I-Chueh; Farzan, Michael
PLoS ONE, Vol. 7, Issue 3
https://doi.org/10.1371/journal.pone.0034508

HADDOCK: A Protein−Protein Docking Approach Based on Biochemical or Biophysical Information
journal, February 2003

Dominguez, Cyril; Boelens, Rolf; Bonvin, Alexandre M. J. J.
Journal of the American Chemical Society, Vol. 125, Issue 7
https://doi.org/10.1021/ja026939x

RNA folding pathway functional intermediates: their prediction and analysis 1 1Edited by I. Tinoco
journal, September 2001

Shapiro, Bruce A.; Bengali, David; Kasprzak, Wojciech
Journal of Molecular Biology, Vol. 312, Issue 1
https://doi.org/10.1006/jmbi.2001.4931

iFoldRNA: three-dimensional RNA structure prediction and folding
journal, June 2008

Sharma, Shantanu; Ding, Feng; Dokholyan, Nikolay V.
Bioinformatics, Vol. 24, Issue 17
https://doi.org/10.1093/bioinformatics/btn328

Temperature-dependent production of pseudoinfectious dengue reporter virus particles by complementation
journal, November 2008

Ansarah-Sobrinho, Camilo; Nelson, Steevenson; Jost, Christiane A.
Virology, Vol. 381, Issue 1, p. 67-74
https://doi.org/10.1016/j.virol.2008.08.021

Relationship Between Clinical Signs and Transmission of an Infectious Disease and the Implications for Control
journal, May 2011

Charleston, B.; Bankowski, B. M.; Gubbins, S.
Science, Vol. 332, Issue 6030
https://doi.org/10.1126/science.1199884

Helper virus-independent trans-replication of hepatitis C virus-derived minigenome
journal, January 2007

Zhang, Jing; Yamada, Osamu; Yoshida, Hiroshi
Biochemical and Biophysical Research Communications, Vol. 352, Issue 1, p. 170-176
https://doi.org/10.1016/j.bbrc.2006.10.188

In Vivo Bioluminescent Imaging (BLI): Noninvasive Visualization and Interrogation of Biological Processes in Living Animals
journal, December 2010

Close, Dan M.; Xu, Tingting; Sayler, Gary S.
Sensors, Vol. 11, Issue 1
https://doi.org/10.3390/s110100180

Control of Dengue Virus Translation and Replication
book, August 2009

Paranjape, Suman M.; Harris, Eva
Dengue Virus. Current Topics in Microbiology and Immunology
https://doi.org/10.1007/978-3-642-02215-9_2

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes
journal, February 2007

Schaller, T.; Appel, N.; Koutsoudakis, G.
Journal of Virology, Vol. 81, Issue 9
https://doi.org/10.1128/JVI.02144-06

Exclusion of West Nile Virus Superinfection through RNA Replication
journal, September 2009

Zou, G.; Zhang, B.; Lim, P. -Y.
Journal of Virology, Vol. 83, Issue 22
https://doi.org/10.1128/JVI.01205-09

Similar Records in DOE Patents and OSTI.GOV collections:

Fabrication of highly textured lithium cobalt oxide films by rapid thermal annealing

Patent Bates, John B.

Systems and methods are described for fabrication of highly textured lithium cobalt oxide films by rapid thermal annealing. A method of forming a lithium cobalt oxide film includes depositing a film of lithium cobalt oxide on a substrate; rapidly heating the film of lithium cobalt oxide to a target temperature; and maintaining the film of lithium cobalt oxide at the target temperature for a target annealing time of at most, approximately 60 minutes. The systems and methods provide advantages because they require less time to implement and are, therefore less costly than previous techniques.
Full Text Available
Fabrication of highly textured lithium cobalt oxide films by rapid thermal annealing

Patent Bates, John B [Marietta, GA]

Systems and methods are described for fabrication of highly textured lithium cobalt oxide films by rapid thermal annealing. A method of forming a lithium cobalt oxide film includes depositing a film of lithium cobalt oxide on a substrate; rapidly heating the film of lithium cobalt oxide to a target temperature; and maintaining the film of lithium cobalt oxide at the target temperature for a target annealing time of at most, approximately 60 minutes. The systems and methods provide advantages because they require less time to implement and are, therefore less costly than previous techniques.
Full Text Available
Fabrication of highly textured lithium cobalt oxide films by rapid thermal annealing

Patent Bates, John B [Marietta, GA]

Systems and methods are described for fabrication of highly textured lithium cobalt oxide films by rapid thermal annealing. A method of forming a lithium cobalt oxide film includes depositing a film of lithium cobalt oxide on a substrate; rapidly heating the film of lithium cobalt oxide to a target temperature; and maintaining the film of lithium cobalt oxide at the target temperature for a target annealing time of at most, approximately 60 minutes. The systems and methods provide advantages because they require less time to implement and are, therefore less costly than previous techniques.
Full Text Available
Highly conductive thermoplastic composites for rapid production of fuel cell bipolar plates

Patent Huang, Jianhua [Blacksburg, VA]; Baird, Donald G [Blacksburg, VA]; McGrath, James E [Blacksburg, VA]

A low cost method of fabricating bipolar plates for use in fuel cells utilizes a wet lay process for combining graphite particles, thermoplastic fibers, and reinforcing fibers to produce a plurality of formable sheets. The formable sheets are then molded into a bipolar plates with features impressed therein via the molding process. The bipolar plates formed by the process have conductivity in excess of 150 S/cm and have sufficient mechanical strength to be used in fuel cells. The bipolar plates can be formed as a skin/core laminate where a second polymer material is used on the skin surface which providesmore » « less
Full Text Available
Methods of treating Parkinson's disease using viral vectors

Patent Bankiewicz, Krystof; Cunningham, Janet

Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.
Full Text Available

Similar Records

Title: Rapid and highly fieldable viral diagnostic

Abstract

Citation Formats

Device for depletion of the leukocyte content of blood and blood components patent, May 1990

Device and method for depletion of the leukocyte content of blood and blood components patent, May 1990

Method and apparatus for sustaining viability of biological cells on a substrate patent, December 2011

Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures patent-application, October 2004

Tracking Gene Expression after DNA Delivery Using Spatially Indexed Nanofiber Arrays journal, July 2004

Inducible RNA Interference-Mediated Gene Silencing Using Nanostructured Gene Delivery Arrays journal, December 2007

Functional RNA Elements in the Dengue Virus Genome journal, September 2011

Development of Dengue type-2 virus replicons expressing GFP reporter gene in study of viral RNA replication journal, February 2012

Identification of Cis -Acting Elements in the 3′-Untranslated Region of the Dengue Virus Type 2 RNA That Modulate Translation and Replication journal, April 2011

Insights into dengue virus genome replication journal, September 2010

cis- and trans-Acting Elements in Flavivirus RNA Replication journal, April 2000

Hepatitis C virus replicons: dinosaurs still in business? journal, January 2009

The Foot-and-Mouth Disease Virus cis-Acting Replication Element (cre) Can Be Complemented in trans within Infected Cells journal, February 2003

Cis-active RNA elements (CREs) and picornavirus RNA replication journal, February 2009

Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine journal, October 2007

Novel Replicon-Based Reporter Gene Assay for Detection of Rubella Virus in Clinical Specimens journal, February 2005

High-throughput assay using a GFP-expressing replicon for SARS-CoV drug discovery journal, November 2008

Bioluminescent bioreporter integrated circuits: potentially small, rugged and inexpensive whole-cell biosensors for remote environmental monitoring journal, January 2004

IFITM Proteins Restrict Antibody-Dependent Enhancement of Dengue Virus Infection journal, March 2012

HADDOCK: A Protein−Protein Docking Approach Based on Biochemical or Biophysical Information journal, February 2003

RNA folding pathway functional intermediates: their prediction and analysis 1 1Edited by I. Tinoco journal, September 2001

iFoldRNA: three-dimensional RNA structure prediction and folding journal, June 2008

Temperature-dependent production of pseudoinfectious dengue reporter virus particles by complementation journal, November 2008

Relationship Between Clinical Signs and Transmission of an Infectious Disease and the Implications for Control journal, May 2011

Helper virus-independent trans-replication of hepatitis C virus-derived minigenome journal, January 2007

In Vivo Bioluminescent Imaging (BLI): Noninvasive Visualization and Interrogation of Biological Processes in Living Animals journal, December 2010

Control of Dengue Virus Translation and Replication book, August 2009

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes journal, February 2007

Exclusion of West Nile Virus Superinfection through RNA Replication journal, September 2009

Device for depletion of the leukocyte content of blood and blood components
patent, May 1990

Device and method for depletion of the leukocyte content of blood and blood components
patent, May 1990

Method and apparatus for sustaining viability of biological cells on a substrate
patent, December 2011

Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures
patent-application, October 2004

Tracking Gene Expression after DNA Delivery Using Spatially Indexed Nanofiber Arrays
journal, July 2004

Inducible RNA Interference-Mediated Gene Silencing Using Nanostructured Gene Delivery Arrays
journal, December 2007

Functional RNA Elements in the Dengue Virus Genome
journal, September 2011

Development of Dengue type-2 virus replicons expressing GFP reporter gene in study of viral RNA replication
journal, February 2012

Identification of Cis -Acting Elements in the 3′-Untranslated Region of the Dengue Virus Type 2 RNA That Modulate Translation and Replication
journal, April 2011

Insights into dengue virus genome replication
journal, September 2010

cis- and trans-Acting Elements in Flavivirus RNA Replication
journal, April 2000

Hepatitis C virus replicons: dinosaurs still in business?
journal, January 2009

The Foot-and-Mouth Disease Virus cis-Acting Replication Element (cre) Can Be Complemented in trans within Infected Cells
journal, February 2003

Cis-active RNA elements (CREs) and picornavirus RNA replication
journal, February 2009

Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine
journal, October 2007

Novel Replicon-Based Reporter Gene Assay for Detection of Rubella Virus in Clinical Specimens
journal, February 2005

High-throughput assay using a GFP-expressing replicon for SARS-CoV drug discovery
journal, November 2008

Bioluminescent bioreporter integrated circuits: potentially small, rugged and inexpensive whole-cell biosensors for remote environmental monitoring
journal, January 2004

IFITM Proteins Restrict Antibody-Dependent Enhancement of Dengue Virus Infection
journal, March 2012

HADDOCK: A Protein−Protein Docking Approach Based on Biochemical or Biophysical Information
journal, February 2003

RNA folding pathway functional intermediates: their prediction and analysis 1 1Edited by I. Tinoco
journal, September 2001

iFoldRNA: three-dimensional RNA structure prediction and folding
journal, June 2008

Temperature-dependent production of pseudoinfectious dengue reporter virus particles by complementation
journal, November 2008

Relationship Between Clinical Signs and Transmission of an Infectious Disease and the Implications for Control
journal, May 2011

Helper virus-independent trans-replication of hepatitis C virus-derived minigenome
journal, January 2007

In Vivo Bioluminescent Imaging (BLI): Noninvasive Visualization and Interrogation of Biological Processes in Living Animals
journal, December 2010

Control of Dengue Virus Translation and Replication
book, August 2009

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes
journal, February 2007

Exclusion of West Nile Virus Superinfection through RNA Replication
journal, September 2009