Identification and use of genes encoding amatoxin and phallotoxin
Abstract
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.
- Inventors:
- Issue Date:
- Research Org.:
- Michigan State Univ., East Lansing, MI (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1335867
- Patent Number(s):
- 9518097
- Application Number:
- 12/268,229
- Assignee:
- Board of Trustees of Michigan State University (East Lansing
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- FG02-91ER20021
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2008 Nov 10
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, and Scott-Craig, John S.. Identification and use of genes encoding amatoxin and phallotoxin. United States: N. p., 2016.
Web.
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, & Scott-Craig, John S.. Identification and use of genes encoding amatoxin and phallotoxin. United States.
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, and Scott-Craig, John S.. Tue .
"Identification and use of genes encoding amatoxin and phallotoxin". United States. https://www.osti.gov/servlets/purl/1335867.
@article{osti_1335867,
title = {Identification and use of genes encoding amatoxin and phallotoxin},
author = {Hallen, Heather E. and Walton, Jonathan D. and Luo, Hong and Scott-Craig, John S.},
abstractNote = {The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {12}
}
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