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Title: Identification and use of genes encoding amatoxin and phallotoxin

Abstract

The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.

Inventors:
; ; ;
Issue Date:
Research Org.:
Board of Trustees of Michigan State University, East Lansing, MI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1335867
Patent Number(s):
9,518,097
Application Number:
12/268,229
Assignee:
Board of Trustees of Michigan State University (East Lansing CHO
DOE Contract Number:  
FG02-91ER20021
Resource Type:
Patent
Resource Relation:
Patent File Date: 2008 Nov 10
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Hallen, Heather E., Walton, Jonathan D., Luo, Hong, and Scott-Craig, John S. Identification and use of genes encoding amatoxin and phallotoxin. United States: N. p., 2016. Web.
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, & Scott-Craig, John S. Identification and use of genes encoding amatoxin and phallotoxin. United States.
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, and Scott-Craig, John S. Tue . "Identification and use of genes encoding amatoxin and phallotoxin". United States. https://www.osti.gov/servlets/purl/1335867.
@article{osti_1335867,
title = {Identification and use of genes encoding amatoxin and phallotoxin},
author = {Hallen, Heather E. and Walton, Jonathan D. and Luo, Hong and Scott-Craig, John S.},
abstractNote = {The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {12}
}

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