Identification and use of genes encoding amatoxin and phallotoxin
Abstract
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.
- Inventors:
- Issue Date:
- Research Org.:
- Michigan State Univ., East Lansing, MI (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1335867
- Patent Number(s):
- 9518097
- Application Number:
- 12/268,229
- Assignee:
- Board of Trustees of Michigan State University (East Lansing
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- FG02-91ER20021
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2008 Nov 10
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, and Scott-Craig, John S. Identification and use of genes encoding amatoxin and phallotoxin. United States: N. p., 2016.
Web.
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, & Scott-Craig, John S. Identification and use of genes encoding amatoxin and phallotoxin. United States.
Hallen, Heather E., Walton, Jonathan D., Luo, Hong, and Scott-Craig, John S. Tue .
"Identification and use of genes encoding amatoxin and phallotoxin". United States. https://www.osti.gov/servlets/purl/1335867.
@article{osti_1335867,
title = {Identification and use of genes encoding amatoxin and phallotoxin},
author = {Hallen, Heather E. and Walton, Jonathan D. and Luo, Hong and Scott-Craig, John S.},
abstractNote = {The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {12}
}
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Works referenced in this record:
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
patent, July 1987
- Mullis, Kary B.; Erlich, Henry A.; Arnheim, Norman
- US Patent Document 4,683,195
Process for amplifying nucleic acid sequences
patent, July 1987
- Mullis, Kary B.
- US Patent Document 4,683,202
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
patent, October 1990
- Mullis, Kary B.; Erlich, Henry A.; Gelfand, David H.
- US Patent Document 4,965,188
Process for direct sequencing during template amplification
patent, July 1999
- Koster, Hubert; Van Den Boom, Dirk Johannes; Ruppert, Andreas
- US Patent Document 5,928,906
Use of Galerina marginata genes and proteins for peptide production
patent, March 2016
- Hallen-Adams, Heather E.; Scott-Craig, John S.; Walton, Jonathan D.
- US Patent Document 9,273,100
Diagnostic Detection of Nucleic Acids
patent-application, August 2001
- Urnovitz, Howard B.
- US Patent Application 08/943607; 20010014445
Random-primed reverse transcriptase-in vitro transcription method for rna amplification
patent-application, April 2004
- Ziman, Michael; Davis, Collen P.
- US Patent Application 10/432176; 20040081978
Methods for amplifying polymeric nucleic acids
patent-application, November 2005
- Behlke, Mark A.; Walder, Joseph A.; Manthey, Jeffrey A.
- US Patent Application 10/911652; 20050255486
Polymorphic markers and methods of genotyping corn
patent-application, June 2006
- Wu, Kunsheng
- US Patent Application 11/218305; 20060141495
Nucleic Acid Sample Purification and Enrichment with a Thermo-Affinity Microfluidic Sub-Circuit
patent-application, March 2008
- Yershov, Gennadiy M.; Kukhtin, Alexander; Chernov, Boris K.
- US Patent Application 11/744112; 20080076677
Annotated Plant Genes
patent-application, April 2009
- Kovalic, David; Liu, Jingdong
- US Patent Application 09/684016; 20090093620
Use Of Galerina Marginata Genes And Proteins For Peptide Production
patent-application, November 2012
- Hallen-Adams, Heather E.; Scott-Craig, John S.; Walton, Jonathan D.
- US Patent Application 13/362561; 20120276588