Title: System and method for detecting components of a mixture including tooth elements for alignment

Abstract

Examples are described including assay platforms having tooth elements. An impinging element may sequentially engage tooth elements on the assay platform to sequentially align corresponding detection regions with a detection unit. In this manner, multiple measurements may be made of detection regions on the assay platform without necessarily requiring the starting and stopping of a motor.

Inventors:

Sommer, Gregory Jon; Schaff, Ulrich Y.

Issue Date:

2016-11-22

Research Org.:

Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1333223

Patent Number(s):

9500579

Application Number:

14/256,294

Assignee:

Sandia Corporation (Albuquerque, NM)

Patent Classifications (CPCs):

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

B01L2200/143 - Quality control, feedback systems
B01L2200/025 - Align devices or objects to ensure defined positions relative to each other

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N21/07 - Centrifugal type cuvettes
G01N35/04 - Details of the conveyor system {
G01N21/59 - Transmissivity
G01N2201/0415 - Carrusel, sequential
G01N2035/0449 - {using centrifugal transport of liquid}
G01N2035/00237 - {Handling microquantities of analyte, e.g. microvalves, capillary networks}

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

B01L2400/0409 - centrifugal forces
B01L2300/0803 - Disc shape

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N35/025 - {having a carousel or turntable for reaction cells or cuvettes}
G01N2035/1034 - {Transferring microquantities of liquid}
G01N35/00069 - {whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk}
G01N21/00 - Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
G01N21/253 - {for batch operation, i.e. multisample apparatus
G01N21/6452 - {Individual samples arranged in a regular 2D-array, e.g. multiwell plates}

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

B01L3/5027 - {by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N21/76 - Chemiluminescence
G01N21/64 - Fluorescence

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DOE Contract Number:  

AC04-94AL85000

Resource Type:

Patent

Resource Relation:

Patent File Date: 2014 Apr 18

Country of Publication:

United States

Language:

English

Subject:

47 OTHER INSTRUMENTATION; 42 ENGINEERING