Global to push GA events into
skip to main content

Title: Compositions and methods for increased ethanol titer from biomass

The present application discloses the identification of novel I. orientalis ADH1, ADHa, and ADHb genes, and the production and characterization of genetically modified yeast cells in which these genes were altered. Provided herein are isolated I. orientalis ADH1, ADHa, and ADHb polynucleotides and polypeptides, genetically modified yeast cells that overexpress I. orientalis ADH1 and/or contain deletions or disruptions of ADHa and/or ADHb, and methods of using culturing these modified cells to produce ethanol.
Inventors:
;
Issue Date:
OSTI Identifier:
1332276
Assignee:
Cargill, Incorporated (Wayzata, MN) GFO
Patent Number(s):
9,493,793
Application Number:
13/988,899
Contract Number:
FC36-07GO17055
Resource Relation:
Patent File Date: 2011 Nov 22
Research Org:
Cargill, Incorporated, Wayzata, MN (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 09 BIOMASS FUELS

Works referenced in this record:

Evolution of a glucose-regulated ADH gene in the genus Saccharomyces
journal, March 2000

The alcohol dehydrogenases of Saccharomyces cerevisiae: a comprehensive review
journal, November 2008

Enhanced ethanol production from sugarcane juice by galactose adaptation of a newly isolated thermotolerant strain of Pichia kudriavzevii
journal, May 2011
  • Dhaliwal, Sandeep Singh; Oberoi, Harinder Singh; Sandhu, Simranjeet Kaur
  • Bioresource Technology, Vol. 102, Issue 10, p. 5968-5975
  • DOI: 10.1016/j.biortech.2011.02.015

Effect of lignocellulosic inhibitory compounds on growth and ethanol fermentation of newly-isolated thermotolerant Issatchenkia orientalis
journal, September 2011