skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry

Abstract

The production and use of semiconducting nanopost arrays made by nanofabrication is described herein. These nanopost arrays (NAPA) provide improved laser ionization yields and controllable fragmentation with switching or modulation capabilities for mass spectrometric detection and identification of samples deposited on them.

Inventors:
; ; ;
Issue Date:
Research Org.:
George Washington Univ., Washington, DC (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1331181
Patent Number(s):
9490113
Application Number:
12/755,769
Assignee:
The George Washington University (Washington, DC)
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
DOE Contract Number:  
FG02-01ER15129
Resource Type:
Patent
Resource Relation:
Patent File Date: 2010 Apr 07
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 77 NANOSCIENCE AND NANOTECHNOLOGY

Citation Formats

Vertes, Akos, Walker, Bennett N., Stolee, Jessica A., and Retterer, Scott T. Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry. United States: N. p., 2016. Web.
Vertes, Akos, Walker, Bennett N., Stolee, Jessica A., & Retterer, Scott T. Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry. United States.
Vertes, Akos, Walker, Bennett N., Stolee, Jessica A., and Retterer, Scott T. Tue . "Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry". United States. https://www.osti.gov/servlets/purl/1331181.
@article{osti_1331181,
title = {Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry},
author = {Vertes, Akos and Walker, Bennett N. and Stolee, Jessica A. and Retterer, Scott T.},
abstractNote = {The production and use of semiconducting nanopost arrays made by nanofabrication is described herein. These nanopost arrays (NAPA) provide improved laser ionization yields and controllable fragmentation with switching or modulation capabilities for mass spectrometric detection and identification of samples deposited on them.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {11}
}

Patent:

Save / Share:

Works referenced in this record:

Assessment of laser-induced thermal load on silicon nanostructures based on ion desorption yields
journal, July 2010


Nanophotonic Ion Production from Silicon Microcolumn Arrays
journal, January 2009


High Sensitivity and Analyte Capture with Desorption/Ionization Mass Spectrometry on Silylated Porous Silicon
journal, August 2004


Surface nanostructuring of silicon
journal, July 2003


Surfactant-Enhanced Desorption/Ionization on Silicon Mass Spectrometry
journal, January 2006


Matrix-assisted laser desorption/ionization of peptides on AnchorChip™ targets with α-cyano-4-hydroxycinnamic acid and nitrocellulose as matrix
journal, January 2005


Internal Energy Transfer in Laser Desorption/Ionization from Silicon Nanowires
journal, July 2006


Surface Modification and Laser Pulse Length Effects on Internal Energy Transfer in DIOS
journal, December 2005


Growth and application of highly ordered array of vertical nanoposts
journal, January 2006


Femtosecond laser-induced formation of spikes on silicon
journal, April 2000


Desorption/ionization mass spectrometry on array of silicon microtips
journal, January 2005

  • Gorecka-Drzazga, Anna; Dziuban, Jan; Drzazga, Wlodzimierz
  • Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures, Vol. 23, Issue 2
  • https://doi.org/10.1116/1.1861046

Desorption/Ionization on Silicon Time-of-Flight/Time-of-Flight Mass Spectrometry
journal, May 2003


Comparison of structure and properties of femtosecond and nanosecond laser-structured silicon
journal, March 2004


Adjustable Fragmentation in Laser Desorption/Ionization from Laser-Induced Silicon Microcolumn Arrays
journal, August 2006


Tailoring Nanoparticle Surface Chemistry to Enhance Laser Desorption Ionization of Peptides and Proteins
journal, October 2007


Improved broadband and quasi-omnidirectional anti-reflection properties with biomimetic silicon nanostructures
journal, December 2007


Near-field fluorescence imaging by localized field enhancement near a sharp probe tip
journal, April 2000


Polarization sensitivity of optical resonant dipole antennas
journal, January 2008


Single Quantum Dot Coupled to a Scanning Optical Antenna: A Tunable Superemitter
journal, June 2005


Plasmonic laser antenna
journal, August 2006


Optical antennas: Resonators for local field enhancement
journal, October 2003


Ballistic-Diffusive Heat-Conduction Equations
journal, March 2001


Field enhancement in apertureless near-field scanning optical microscopy
journal, January 2001


Enhancement and Quenching of Single-Molecule Fluorescence
journal, March 2006


Interaction of powerful laser radiation with the surfaces of semiconductors and metals: nonlinear optical effects and nonlinear optical diagnostics
journal, December 1985


Contributions of mass spectrometry to peptide and protein structure
journal, October 1988


Silicon electron emitters fabricated by ultraviolet laser pulses
journal, February 2006


Correlation of Kinetic Energy Losses in High-Energy Collision-Induced Dissociation with Observed Peptide Product Ions
journal, January 1996


Optical antennas direct single-molecule emission
journal, March 2008


High-Energy Fragmentation in Nanophotonic Ion Production by Laser-Induced Silicon Microcolumn Arrays
journal, October 2009


Nanoscale Atmospheric Pressure Laser Ablation-Mass Spectrometry
journal, April 2001


Near-Field Fluorescence Microscopy Based on Two-Photon Excitation with Metal Tips
journal, May 1999


Femtosecond laser near-field ablation from gold nanoparticles
journal, December 2005


New dimension in nano-imaging: breaking through the diffraction limit with scanning near-field optical microscopy
journal, November 2004


Direct Protein Detection from Biological Media through Electrospray-Assisted Laser Desorption Ionization/Mass Spectrometry
journal, May 2006


Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
journal, April 2005


Desorption−Ionization Mass Spectrometry Using Deposited Nanostructured Silicon Films
journal, March 2001