Two-dimensional fourier transform spectrometer
The present invention relates to a system and methods for acquiring two-dimensional Fourier transform (2D FT) spectra. Overlap of a collinear pulse pair and probe induce a molecular response which is collected by spectral dispersion of the signal modulated probe beam. Simultaneous collection of the molecular response, pulse timing and characteristics permit real time phasing and rapid acquisition of spectra. Full spectra are acquired as a function of pulse pair timings and numerically transformed to achieve the full frequency-frequency spectrum. This method demonstrates the ability to acquire information on molecular dynamics, couplings and structure in a simple apparatus. Multi-dimensional methods can be used for diagnostic and analytical measurements in the biological, biomedical, and chemical fields.
- Issue Date:
- OSTI Identifier:
- 1330327
- Assignee:
- Massachusetts Institute of Technology (Cambridge, MA) CHO
- Patent Number(s):
- 9,476,768
- Application Number:
- 13/955,158
- Contract Number:
- FG02-99ER14988
- Resource Relation:
- Patent File Date: 2013 Jul 31
- Research Org:
- Massachusetts Institute of Technology, Cambridge, MA (United States)
- Sponsoring Org:
- USDOE
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS
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Works referenced in this record:
Automated 2D IR spectroscopy using a mid-IR pulse shaper and application of this technology to the human islet amyloid polypeptide
journal, May 2007
journal, May 2007
- Shim, S.-H.; Strasfeld, D. B.; Ling, Y. L.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 36, p. 14197-14202