Identification of cancer protein biomarkers using proteomic techniques
Abstract
The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.
- Inventors:
- Issue Date:
- Research Org.:
- Yale Univ., New Haven, CT (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1329309
- Patent Number(s):
- 9470688
- Application Number:
- 14/602,916
- Assignee:
- Yale University (New Haven, CT
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- FG02-ER63462
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2015 Jul 22
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES
Citation Formats
Mor, Gil G., Ward, David C., and Bray-Ward, Patricia. Identification of cancer protein biomarkers using proteomic techniques. United States: N. p., 2016.
Web.
Mor, Gil G., Ward, David C., & Bray-Ward, Patricia. Identification of cancer protein biomarkers using proteomic techniques. United States.
Mor, Gil G., Ward, David C., and Bray-Ward, Patricia. Tue .
"Identification of cancer protein biomarkers using proteomic techniques". United States. https://www.osti.gov/servlets/purl/1329309.
@article{osti_1329309,
title = {Identification of cancer protein biomarkers using proteomic techniques},
author = {Mor, Gil G. and Ward, David C. and Bray-Ward, Patricia},
abstractNote = {The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {10}
}
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