Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification
Abstract
Provided herein are methods and systems for assembling, solubilizing and/or purifying a membrane associated protein in a nanolipoprotein particle, which comprise a temperature transition cycle performed in presence of a detergent, wherein during the temperature transition cycle the nanolipoprotein components are brought to a temperature above and below the gel to liquid crystalling transition temperature of the membrane forming lipid of the nanolipoprotein particle.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1327989
- Patent Number(s):
- 9458191
- Application Number:
- 14/536,513
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC52-07NA27344
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2014 Nov 07
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Chromy, Brett A., Henderson, Paul, and Hoeprich, Jr, Paul D. Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification. United States: N. p., 2016.
Web.
Chromy, Brett A., Henderson, Paul, & Hoeprich, Jr, Paul D. Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification. United States.
Chromy, Brett A., Henderson, Paul, and Hoeprich, Jr, Paul D. Tue .
"Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification". United States. https://www.osti.gov/servlets/purl/1327989.
@article{osti_1327989,
title = {Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification},
author = {Chromy, Brett A. and Henderson, Paul and Hoeprich, Jr, Paul D.},
abstractNote = {Provided herein are methods and systems for assembling, solubilizing and/or purifying a membrane associated protein in a nanolipoprotein particle, which comprise a temperature transition cycle performed in presence of a detergent, wherein during the temperature transition cycle the nanolipoprotein components are brought to a temperature above and below the gel to liquid crystalling transition temperature of the membrane forming lipid of the nanolipoprotein particle.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 04 00:00:00 EDT 2016},
month = {Tue Oct 04 00:00:00 EDT 2016}
}
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Works referenced in this record:
Muramyldipeptide derivatives
patent, March 1982
- Shiba, Tetsuo; Kotani, Shozo; Yamamura, Yuichi
- US Patent Document 4,317,771
Method for making liposomes of enhanced entrapping capacity toward foreign substances to be encapsulated
patent, February 1995
- Schneider, Michel; Tournier, Herve; Hyacinthe, Roland
- US Patent Document 5,393,530
Surface plasmon resonance systems and methods having a variable charge density layer
patent, March 2006
- Franzen, Stefan; Brewer, Scott
- US Patent Document 7,015,471
Membrane scaffold proteins
patent, May 2006
- Sligar, Stephen G.; Bayburt, Timothy H.
- US Patent Document 7,048,949
Membrane scaffold proteins
patent, August 2006
- Sligar, Stephen G.; Bayburt, Timothy H.; Schuler, Mary A.
- US Patent Document 7,083,958
Copper-catalysed ligation of azides and acetylenes
patent, May 2008
- Sharpless, K. Barry; Fokin, Valery; Rostovtsev, Vsevold A.
- US Patent Document 7,375,234
Cell-free synthesis of membrane bound polypeptides
patent, May 2012
- Swartz, James R.; Wuu, Jessica
- US Patent Document 8,183,010
Photothermal detection of nucleic acid hybridization
patent-application, September 2004
- Franzen, Stefan; Feldheim, Daniel
- US Patent Application 10/759496; 20040180369
Method to ameliorate osteolysis and metastasis
patent-application, November 2005
- Mundy, Gregory; Yoneda, Yoshiyuki; Guise, Theresa
- US Patent Application 11/109470; 20050244414
Nanoparticle-Based vaccine delivery system containing adjuvant
patent-application, August 2006
- Mumper, Russell; Cui, Zhengrong
- US Patent Application 10/528817; 20060189554
Membrane scaffold proteins and tethered membrane proteins
patent-application, September 2006
- Sligar, Stephen; Bayburt, Timothy
- US Patent Application 11/439458; 20060211092
In Vitro Protein Synthesis Systems For Membrane Proteins That Include Adolipoproteins And Phospholipid-Adolipoprotein Particles
patent-application, May 2007
- Kudlicki, Wieslaw; Fletcher, Julia; Katzen, Federico
- US Patent Application 11/535960; 20070117179
Nanoparticle-based vaccine delivery system containing adjuvant
patent-application, May 2008
- Mumper, Russell; Cui, Zhengrong
- US Patent Application 12/010468; 20080124350
Nanolipoprotein Particles And Related Methods And Systems For Protein Capture, Solubilization, And/Or Purification
patent-application, July 2009
- Chromy, Brett A.; Henderson, Paul; Hoeprich, Jr., Paul D.
- US Patent 12/352548; 20090192299
Nanolipoprotein Particles and Related Compositions, Methods and Systems
patent-application, December 2009
- Hoeprich, Paul D.; Fischer, Nicholas O.; Mason, Peter W.
- US Patent Application 12/469533; 20090311276
Photocatalytic Hydrogen Production And Polypeptides Capable Of Same
patent-application, August 2010
- Yacoby, Iftach; Gazit, Ehud; Nelson, Nathan
- US Patent Application 12/670407; 20100203609
Overview of Protein Structural and Functional Folds
book, February 2004
- Sun, Peter D.; Foster, Christine E.; Boyington, Jeffrey C.
- Current Protocols in Protein Science, Vol. 35, p. 17.1.1.1–17.1.189
Ab Initio Protein Structure Prediction
book, January 2009
- Lee, Jooyoung; Wu, Sitao; Zhang, Yang
- From Protein Structure to Function with Bioinformatics
Predictable difficulty or difficulty to predict: Letter to the Editor
journal, December 2010
- Arányi, Tamás; Fülöp, Krisztina; Symmons, Orsolya
- Protein Science, Vol. 20, Issue 1
Synthesis and Characterization of Chelator-Lipids for Reversible Immobilization of Engineered Proteins at Self-Assembled Lipid Interfaces
journal, September 1994
- Schmitt, Lutz; Dietrich, Christian; Tampe, Robert
- Journal of the American Chemical Society, Vol. 116, Issue 19, p. 8485-8491
Detection of DNA hybridization on indium tin oxide surfaces
journal, August 2007
- Moses, Selina; Brewer, Scott H.; Kraemer, Stephan
- Sensors and Actuators B: Chemical, Vol. 125, Issue 2, p. 574-580
High-Sensitivity Detection of DNA Hybridization on Microarrays Using Resonance Light Scattering
journal, April 2002
- Bao, Paul; Frutos, Anthony G.; Greef, Charles
- Analytical Chemistry, Vol. 74, Issue 8
Exploring the new world of the genome with DNA microarrays
journal, January 1999
- Brown, Patrick O.; Botstein, David
- Nature Genetics, Vol. 21, Issue S1
Formation of Thiolate and Phosphonate Adlayers on Indium−Tin Oxide: Optical and Electronic Characterization
journal, September 2002
- Brewer, Scott H.; Brown, Derek A.; Franzen, Stefan
- Langmuir, Vol. 18, Issue 18
Progress towards the easier use of P450 enzymes
journal, January 2006
- Chefson, Amandine; Auclair, Karine
- Molecular BioSystems, Vol. 2, Issue 10
Some Observations on the Type I and Type II Microsomal Binding Spectra
journal, January 1971
- Gorrod, J. W.; Disley, L. G.; Temple, D. J.
- Xenobiotica, Vol. 1, Issue 4-5
Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase
journal, April 2002
- Chen, J.-S.; Berenbaum, M. R.; Schuler, M. A.
- Insect Molecular Biology, Vol. 11, Issue 2, p. 175-186
How Translocons Select Transmembrane Helices
journal, June 2008
- White, Stephen H.; von Heijne, Gunnar
- Annual Review of Biophysics, Vol. 37, Issue 1
Noncytopathic Replication of Venezuelan Equine Encephalitis Virus and Eastern Equine Encephalitis Virus Replicons in Mammalian Cells
journal, May 2005
- Petrakova, O.; Volkova, E.; Gorchakov, R.
- Journal of Virology, Vol. 79, Issue 12
Construction and characterization of a second-generation pseudoinfectious West Nile virus vaccine propagated using a new cultivation system
journal, May 2008
- Widman, Douglas G.; Ishikawa, Tomohiro; Fayzulin, Rafik
- Vaccine, Vol. 26, Issue 22, p. 2762-2771
Immobilization of His-Tagged Proteins on Nickel-Chelating Nanolipoprotein Particles
journal, March 2009
- Fischer, Nicholas O.; Blanchette, Craig D.; Chromy, Brett A.
- Bioconjugate Chemistry, Vol. 20, Issue 3
Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles
journal, February 2010
- Sperling, R. A.; Parak, W. J.
- Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 368, Issue 1915, p. 1333-1383
Three-Dimensional Graphene Nano-Networks with High Quality and Mass Production Capability via Precursor-Assisted Chemical Vapor Deposition
journal, May 2013
- Yoon, Jong-Chul; Lee, Jung-Soo; Kim, Sun-I
- Scientific Reports, Vol. 3, Issue 1
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
journal, April 2007
- Whorton, M. R.; Bokoch, M. P.; Rasmussen, S. G. F.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 18, p. 7682-7687
Synthesis of Native Proteins by Chemical Ligation
journal, June 2000
- Dawson, Philip E.; Kent, Stephen B. H.
- Annual Review of Biochemistry, Vol. 69, Issue 1
Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems
journal, January 2003
- Terpe, K.
- Applied Microbiology and Biotechnology, Vol. 60, Issue 5, p. 523-533
The growing impact of click chemistry on drug discovery
journal, December 2003
- Kolb, Hartmuth C.; Sharpless, K. Barry
- Drug Discovery Today, Vol. 8, Issue 24, p. 1128-1137
Large-scale profiling of protein palmitoylation in mammalian cells
journal, January 2009
- Martin, Brent R.; Cravatt, Benjamin F.
- Nature Methods, Vol. 6, Issue 2, p. 135-138
Systems for orthogonal self-assembly of electroactive monolayers on Au and ITO: an approach to molecular electronics
journal, July 1995
- Gardner, Timothy J.; Frisbie, C. Daniel; Wrighton, Mark S.
- Journal of the American Chemical Society, Vol. 117, Issue 26, p. 6927-6933
The Efficiency of Light-Directed Synthesis of DNA Arrays on Glass Substrates
journal, June 1997
- McGall, Glenn H.; Barone, Anthony D.; Diggelmann, Martin
- Journal of the American Chemical Society, Vol. 119, Issue 22, p. 5081-5090
Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array
journal, October 1999
- Singh-Gasson, Sangeet; Green, Roland D.; Yue, Yongjian
- Nature Biotechnology, Vol. 17, Issue 10, p. 974-978
CpG DNA induces stronger immune responses with less toxicity than other adjuvants
journal, March 2000
- Weeratna, Risini D.; McCluskie, Michael J.; Xu, Yu
- Vaccine, Vol. 18, Issue 17, p. 1755-1762
Induction of tumor necrosis factor-α in solid tumor region by the orally administered synthetic muramyl dipeptide analogue, romurtide
journal, January 2001
- Ueda, Hiroshi; Yamazaki, Masatoshi
- International Immunopharmacology, Vol. 1, Issue 1, p. 97-104
Identification of active methylotroph populations in an acidic forest soil by stable-isotope probing c
journal, August 2002
- Radajewski, Stefan; Prosser, James I.; Nedwell, David B.
- Microbiology, Vol. 148, Issue 8
RNA Stable Isotope Probing, a Novel Means of Linking Microbial Community Function to Phylogeny
journal, November 2002
- Manefield, M.; Whiteley, A. S.; Griffiths, R. I.
- Applied and Environmental Microbiology, Vol. 68, Issue 11
DNA-based stable isotope probing: a link between community structure and function
journal, June 2009
- Uhlík, Ondrej; Jecná, Katerina; Leigh, Mary Beth
- Science of The Total Environment, Vol. 407, Issue 12, p. 3611-3619
Stable isotope probing: Technical considerations when resolving 15N-labeled RNA in gradients
journal, January 2010
- Addison, S. L.; McDonald, I. R.; Lloyd-Jones, G.
- Journal of Microbiological Methods, Vol. 80, Issue 1, p. 70-75
The contribution of macrophyte-derived organic matter to microbial biomass in salt-marsh sediments: Stable carbon isotope analysis of microbial biomarkers
journal, March 1999
- Boschker, H. T. S.; de Brouwer, J. F. C.; Cappenberg, T. E.
- Limnology and Oceanography, Vol. 44, Issue 2
The Isotope Array, a New Tool That Employs Substrate-Mediated Labeling of rRNA for Determination of Microbial Community Structure and Function
journal, November 2003
- Adamczyk, J.; Hesselsoe, M.; Iversen, N.
- Applied and Environmental Microbiology, Vol. 69, Issue 11
Integration of biological networks and gene expression data using Cytoscape
journal, September 2007
- Cline, Melissa S.; Smoot, Michael; Cerami, Ethan
- Nature Protocols, Vol. 2, Issue 10
Specific targeting of a lipophilic prodrug of iododeoxyuridine to parenchymal liver cells using lactosylated reconstituted high density lipoprotein particles
journal, July 1996
- Bijsterbosch, Martin K.; van de Bilt, Hendrika; van Berkel, Theo J. C.
- Biochemical Pharmacology, Vol. 52, Issue 1, p. 113-121
Indium-111 Labeling of Low Density Lipoproteins with the DTPA−Bis(stearylamide): Evaluation as a Potential Radiopharmaceutical for Tumor Localization
journal, January 1996
- Jasanada, François; Urizzi, Pascale; Souchard, Jean-Pierre
- Bioconjugate Chemistry, Vol. 7, Issue 1
In vitro characterization of binding and stability of single-chain Fv Ni-NTA-liposomes
journal, January 2006
- Rüger, Ronny; Müller, Dafne; Fahr, Alfred
- Journal of Drug Targeting, Vol. 14, Issue 8
Preparation and Characterization of Nickel Nanoparticles for Binding to His-tag Proteins and Antigens
journal, December 2006
- Patel, Jigna D.; O’Carra, Ronan; Jones, Julia
- Pharmaceutical Research, Vol. 24, Issue 2
Protein Translocons
journal, February 2003
- Schnell, Danny J.; Hebert, Daniel N.
- Cell, Vol. 112, Issue 4
Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment
journal, October 2004
- Baas, Bradley J.; Denisov, Ilia G.; Sligar, Stephen G.
- Archives of Biochemistry and Biophysics, Vol. 430, Issue 2, p. 218-228
Hydrogen Production by a Hyperthermophilic Membrane-Bound Hydrogenase in Water-Soluble Nanolipoprotein Particles
journal, June 2009
- Baker, Sarah E.; Hopkins, Robert C.; Blanchette, Craig D.
- Journal of the American Chemical Society, Vol. 131, Issue 22
Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks
journal, May 2002
- Bayburt, T. H.; Sligar, S. G.
- Proceedings of the National Academy of Sciences, Vol. 99, Issue 10, p. 6725-6730
Direct linking of microbial populations to specific biogeochemical processes by 13C-labelling of biomarkers
journal, April 1998
- Boschker, H. T. S.; Nold, S. C.; Wellsbury, P.
- Nature, Vol. 392, Issue 6678
Urban aerosols harbor diverse and dynamic bacterial populations
journal, December 2006
- Brodie, E. L.; DeSantis, T. Z.; Parker, J. P. M.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 1, p. 299-304
Cell-free Co-expression of Functional Membrane Proteins and Apolipoprotein, Forming Soluble Nanolipoprotein Particles
journal, July 2008
- Cappuccio, Jenny A.; Blanchette, Craig D.; Sulchek, Todd A.
- Molecular & Cellular Proteomics, Vol. 7, Issue 11
Stable-isotope probing as a tool in microbial ecology
journal, February 2000
- Radajewski, Stefan; Ineson, Philip; Parekh, Nisha R.
- Nature, Vol. 403, Issue 6770, p. 646-649
Evaluation of Nanolipoprotein Particles (NLPs) as an In Vivo Delivery Platform
journal, March 2014
- Fischer, Nicholas O.; Weilhammer, Dina R.; Dunkle, Alexis
- PLoS ONE, Vol. 9, Issue 3
Kinetic properties of recombinant MAO-A on incorporation into phospholipid nanodisks
journal, March 2007
- Cruz, F.; Edmondson, D. E.
- Journal of Neural Transmission, Vol. 114, Issue 6
Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB
journal, July 2006
- DeSantis, T. Z.; Hugenholtz, P.; Larsen, N.
- Applied and Environmental Microbiology, Vol. 72, Issue 7, p. 5069-5072
High-Density Universal 16S rRNA Microarray Analysis Reveals Broader Diversity than Typical Clone Library When Sampling the Environment
journal, March 2007
- DeSantis, Todd Z.; Brodie, Eoin L.; Moberg, Jordan P.
- Microbial Ecology, Vol. 53, Issue 3
An improved synthesis of isopentenyl pyrophosphate
journal, November 1967
- Donninger, C.; Popják, G.
- Biochemical Journal, Vol. 105, Issue 2
Enzyme-catalyzed Synthesis and Degradation of Biopolymers
journal, February 2009
- Hiraishi, Tomohiro; Taguchi, Seiichi
- Mini-Reviews in Organic Chemistry, Vol. 6, Issue 1
Expression of G protein coupled receptors in a cell-free translational system using detergents and thioredoxin-fusion vectors
journal, May 2005
- Ishihara, Goshi; Goto, Mie; Saeki, Mihoro
- Protein Expression and Purification, Vol. 41, Issue 1, p. 27-37
Insertion of Membrane Proteins into Discoidal Membranes Using a Cell-Free Protein Expression Approach
journal, August 2008
- Katzen, Federico; Fletcher, Julia E.; Yang, Jian-Ping
- Journal of Proteome Research, Vol. 7, Issue 8
Biodegradation of Natural Rubber and Related Compounds: Recent Insights into a Hardly Understood Catabolic Capability of Microorganisms
journal, June 2005
- Rose, K.; Steinbuchel, A.
- Applied and Environmental Microbiology, Vol. 71, Issue 6
The Biosynthesis of Natural Rubber
journal, June 1990
- Paterson-Jones, J. C.; Gilliland, M. G.; Van Staden, J.
- Journal of Plant Physiology, Vol. 136, Issue 3, p. 257-263
Transcriptome and gene expression analysis in cold-acclimated guayule (Parthenium argentatum) rubber-producing tissue
journal, July 2012
- Ponciano, Grisel; McMahan, Colleen M.; Xie, Wenshuang
- Phytochemistry, Vol. 79, p. 57-66
Characterization of rubber particles and rubber chain elongation in Taraxacum koksaghyz
journal, January 2010
- Schmidt, Thomas; Lenders, Malte; Hillebrand, Andrea
- BMC Biochemistry, Vol. 11, Issue 1
Phospholipid phase transitions in homogeneous nanometer scale bilayer discs
journal, December 2003
- Shaw, Andrew W.; McLean, Mark A.; Sligar, Stephen G.
- FEBS Letters, Vol. 556, Issue 1-3, p. 260-264
The micromorphology and protein characterization of rubber particles in Ficus carica, Ficus benghalensis and Hevea brasiliensis
journal, March 2003
- Singh, A. P.; Wi, S. G.; Chung, G. C.
- Journal of Experimental Botany, Vol. 54, Issue 384
Indirect electrochemical reduction of nicotinamide coenzymes
journal, December 2004
- Vuorilehto, K.; Lütz, S.; Wandrey, C.
- Bioelectrochemistry, Vol. 65, Issue 1, p. 1-7
Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms
journal, April 1998
- Wallin, Erik; Heijne, Gunnar Von
- Protein Science, Vol. 7, Issue 4
Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species
journal, October 2008
- Xie, Wenshuang; McMahan, Colleen M.; DeGraw, Amanda J.
- Phytochemistry, Vol. 69, Issue 14, p. 2539-2545
The Major Protein of Guayule Rubber Particles Is a Cytochrome P450: CHARACTERIZATION BASED ON cDNA CLONING AND SPECTROSCOPIC ANALYSIS OF THE SOLUBILIZED ENZYME AND ITS REACTION PRODUCTS
journal, April 1995
- Pan, Zhiqiang; Durst, Francis; Werck-Reichhart, Daniele
- Journal of Biological Chemistry, Vol. 270, Issue 15
Gold Nanoparticle-Enhanced Secondary Ion Mass Spectrometry Imaging of Peptides on Self-Assembled Monolayers
journal, March 2006
- Kim, Young-Pil; Oh, Eunkeu; Hong, Mi-Young
- Analytical Chemistry, Vol. 78, Issue 6
Protein tolerance to random amino acid change
journal, June 2004
- Guo, H. H.; Choe, J.; Loeb, L. A.
- Proceedings of the National Academy of Sciences, Vol. 101, Issue 25, p. 9205-9210
Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.
journal, March 1988
- Lazar, E.; Watanabe, S.; Dalton, S.
- Molecular and Cellular Biology, Vol. 8, Issue 3, p. 1247-1252
Functional Analysis of Conserved Histidines in ADP-Glucose Pyrophosphorylase from Escherichia coli
journal, March 1998
- Hill, Margaret A.; Preiss, Jack
- Biochemical and Biophysical Research Communications, Vol. 244, Issue 2, p. 573-577
Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53
journal, February 1999
- Wacey, A. I.; Cooper, D. N.; Liney, D.
- Human Genetics, Vol. 104, Issue 1, p. 15-22
Rubber Elongation Factor (REF), a Major Allergen Component in Hevea brasiliensis Latex Has Amyloid Properties
journal, October 2012
- Berthelot, Karine; Lecomte, Sophie; Estevez, Yannick
- PLoS ONE, Vol. 7, Issue 10
Biochemistry of natural rubber, a vital raw material, emphasizing biosynthetic rate, molecular weight and compartmentalization, in evolutionarily divergent plant species (1963 to 2000)
journal, January 2001
- Cornish, Katrina
- Natural Product Reports, Vol. 18, Issue 2
Protein engineering methods applied to membrane protein targets
journal, October 2012
- Lluis, M. W.; Godfroy, J. I.; Yin, H.
- Protein Engineering Design and Selection, Vol. 26, Issue 2
The Soluble NAD+-Reducing [NiFe]-Hydrogenase from Ralstonia eutropha H16 Consists of Six Subunits and Can Be Specifically Activated by NADPH
journal, April 2005
- Burgdorf, T.; van der Linden, E.; Bernhard, M.
- Journal of Bacteriology, Vol. 187, Issue 9, p. 3122-3132
Hydrogen production by biological processes: a survey of literature
journal, January 2001
- Das, D.
- International Journal of Hydrogen Energy, Vol. 26, Issue 1
Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers
journal, April 2004
- Duan, Hui; Civjan, Natanya R; Sligar, Stephen G
- Archives of Biochemistry and Biophysics, Vol. 424, Issue 2, p. 141-153
Bio-hydrogen production from waste materials
journal, March 2006
- Kapdan, Ilgi Karapinar; Kargi, Fikret
- Enzyme and Microbial Technology, Vol. 38, Issue 5, p. 569-582
The membrane-bound [NiFe]-hydrogenase (Ech) from Methanosarcina barkeri: unusual properties of the iron-sulphur clusters: The membrane-bound [NiFe]-hydrogenase (Ech) from M. barkeri
journal, December 2002
- Kurkin, Sergei; Meuer, Jörn; Koch, Jürgen
- European Journal of Biochemistry, Vol. 269, Issue 24
Characterization of a HoxEFUYH type of [NiFe] hydrogenase from Allochromatium vinosum and some EPR and IR properties of the hydrogenase module
journal, September 2006
- Long, Minnan; Liu, Jingjing; Chen, Zhifeng
- JBIC Journal of Biological Inorganic Chemistry, Vol. 12, Issue 1
The [NiFe]-Hydrogenase of the Cyanobacterium Synechocystis sp. PCC 6803 Works Bidirectionally with a Bias to H 2 Production
journal, July 2011
- McIntosh, Chelsea L.; Germer, Frauke; Schulz, Rüdiger
- Journal of the American Chemical Society, Vol. 133, Issue 29
Intact Functional Fourteen-subunit Respiratory Membrane-bound [NiFe]-Hydrogenase Complex of the Hyperthermophilic Archaeon Pyrococcus furiosus
journal, May 2014
- McTernan, Patrick M.; Chandrayan, Sanjeev K.; Wu, Chang-Hao
- Journal of Biological Chemistry, Vol. 289, Issue 28
Purification and catalytic properties of Ech hydrogenase from Methanosarcina barkeri
journal, October 1999
- Meuer, Jorn; Bartoschek, Stefan; Koch, Jurgen
- European Journal of Biochemistry, Vol. 265, Issue 1
Cyanobacterial-Type, Heteropentameric, NAD+-Reducing NiFe Hydrogenase in the Purple Sulfur Photosynthetic Bacterium Thiocapsa roseopersicina
journal, February 2004
- Rakhely, G.; Kovacs, A. T.; Maroti, G.
- Applied and Environmental Microbiology, Vol. 70, Issue 2
HoxE—a subunit specific for the pentameric bidirectional hydrogenase complex (HoxEFUYH) of cyanobacteria
journal, April 2002
- Schmitz, Oliver; Boison, Gudrun; Salzmann, Heike
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1554, Issue 1-2, p. 66-74
Purification and catalytic properties of a CO-oxidizing:H2-evolving enzyme complex from Carboxydothermus hydrogenoformans: CO-oxidizing:H2-evolving enzyme complex
journal, October 2002
- Soboh, Basem; Linder, Dietmar; Hedderich, Reiner
- European Journal of Biochemistry, Vol. 269, Issue 22
A multisubunit membrane-bound [NiFe] hydrogenase and an NADH-dependent Fe-only hydrogenase in the fermenting bacterium Thermoanaerobacter tengcongensis
journal, July 2004
- Soboh, B.
- Microbiology, Vol. 150, Issue 7
Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C
journal, September 1998
- Barros, Francisco; Gómez-Varela, David; Viloria, Cristina G.
- The Journal of Physiology, Vol. 511, Issue 2, p. 333-346
Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells: role of ET B receptor, NADPH oxidase and caveolin-1
journal, June 2005
- Dong, Feng; Zhang, Xiaochun; Wold, Loren E.
- British Journal of Pharmacology, Vol. 145, Issue 3
Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice
journal, February 2000
- Dumartin, B.; Jaber, M.; Gonon, F.
- Proceedings of the National Academy of Sciences, Vol. 97, Issue 4, p. 1879-1884
Corticotropin Releasing Factor (CRF) Receptor Signaling in the Central Nervous System: New Molecular Targets
journal, August 2006
- Hauger, Richard; Risbrough, Victoria; Brauns, Olaf
- CNS & Neurological Disorders - Drug Targets, Vol. 5, Issue 4
G-Protein-Coupled Receptor Microarrays for Multiplexed Compound Screening
journal, June 2006
- Hong, Yulong; Webb, Brian L.; Pai, Sadashiva
- Journal of Biomolecular Screening, Vol. 11, Issue 4
The Effects of Deleting the Mouse Neurotensin Receptor NTR1 on Central and Peripheral Responses to Neurotensin
journal, January 2002
- Pettibone, Douglas J.; Hess, J. Fred; Hey, Patricia J.
- Journal of Pharmacology and Experimental Therapeutics, Vol. 300, Issue 1
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
journal, January 2005
- Ren, X.-R.; Reiter, E.; Ahn, S.
- Proceedings of the National Academy of Sciences, Vol. 102, Issue 5, p. 1448-1453
Molecular Dynamics Simulations of Discoidal Bilayers Assembled from Truncated Human Lipoproteins
journal, January 2005
- Shih, Amy Y.; Denisov, Ilia G.; Phillips, James C.
- Biophysical Journal, Vol. 88, Issue 1
Novel applications of liposomes
journal, July 1998
- Lasic, D.
- Trends in Biotechnology, Vol. 16, Issue 7
Osmotic shrinkage of giant egg-lecithin vesicles
journal, April 1981
- Boroske, E.; Elwenspoek, M.; Helfrich, W.
- Biophysical Journal, Vol. 34, Issue 1, p. 95-109
Surface changes induced by osmotic shrinkage on large unilamellar vesicles
journal, November 1996
- Disalvo, E. A.; Campos, A. M.; Abuin, E.
- Chemistry and Physics of Lipids, Vol. 84, Issue 1, p. 35-45
Stability of pressure-extruded liposomes made from archaeobacterial ether lipids
journal, November 1994
- Choquet, C. G.; Patel, G. B.; Sprott, G. D.
- Applied Microbiology and Biotechnology, Vol. 42, Issue 2-3, p. 375-384
Mechanical properties and stability measurement of cholesterol-containing liposome on mica by atomic force microscopy
journal, October 2004
- Liang, Xuemei; Mao, Guangzhao; Ng, K. Y. Simon
- Journal of Colloid and Interface Science, Vol. 278, Issue 1, p. 53-62
Steric stabilization of phospholipid vesicles by block copolymers Vesicle flocculation and osmotic swelling caused by monovalent and divalent cations
journal, January 1998
- Kostarelos, Kostas; Luckham, Paul F.; Tadros, Tharwat F.
- Journal of the Chemical Society, Faraday Transactions, Vol. 94, Issue 15
Adjuvants for human vaccines—current status, problems and future prospects
journal, January 1995
- Gupta, Rajesh K.; Siber, George R.
- Vaccine, Vol. 13, Issue 14, p. 1263-1276
The Vaccine Adjuvant Monophosphoryl Lipid A as a TRIF-Biased Agonist of TLR4
journal, June 2007
- Mata-Haro, V.; Cekic, C.; Martin, M.
- Science, Vol. 316, Issue 5831, p. 1628-1632
Taking toll: lipid A mimetics as adjuvants and immunomodulators
journal, October 2002
- Persing, David H.; Coler, Rhea N.; Lacy, Michael J.
- Trends in Microbiology, Vol. 10, Issue 10, p. s32-s37
Generation of immunoliposomes using recombinant single-chain Fv fragments bound to Ni-NTA-liposomes
journal, August 2005
- Rüger, Ronny; Müller, Dafne; Fahr, Alfred
- Journal of Drug Targeting, Vol. 13, Issue 7
Attaching histidine-tagged peptides and proteins to lipid-based carriers through use of metal-ion-chelating lipids
journal, December 2002
- Chikh, Ghania G.; Li, Wai Ming; Schutze-Redelmeier, Marie-Paule
- Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1567, p. 204-212
Vaccine manufacturing: challenges and solutions
journal, November 2006
- Ulmer, Jeffrey B.; Valley, Ulrich; Rappuoli, Rino
- Nature Biotechnology, Vol. 24, Issue 11
Characterization and Purification of Polydisperse Reconstituted Lipoproteins and Nanolipoprotein Particles
journal, July 2009
- Blanchette, Craig; Segelke, Brent; Fischer, Nicholas
- International Journal of Molecular Sciences, Vol. 10, Issue 7
Conjugation to Nickel-Chelating Nanolipoprotein Particles Increases the Potency and Efficacy of Subunit Vaccines to Prevent West Nile Encephalitis
journal, June 2010
- Fischer, Nicholas O.; Infante, Ernesto; Ishikawa, Tomohiro
- Bioconjugate Chemistry, Vol. 21, Issue 6, p. 1018-1022
Two-Dimensional Streptavidin Crystals on Giant Lipid Bilayer Vesicles
journal, May 2002
- Ratanabanangkoon, Pasut; Gropper, Michael; Merkel, Rudolf
- Langmuir, Vol. 18, Issue 11, p. 4270-4276
Specific Interaction and Two-Dimensional Crystallization of Histidine Tagged Yeast RNA Polymerase I on Nickel-Chelating Lipids
journal, March 1998
- Bischler, Nicolas; Balavoine, Fabrice; Milkereit, Philipp
- Biophysical Journal, Vol. 74, Issue 3, p. 1522-1532
Two-Dimensional Crystallization of Histidine-Tagged, HIV-1 Reverse Transcriptase Promoted by a Novel Nickel-Chelating Lipid
journal, September 1994
- Kubalek, Elizabeth W.; Le Grice, Stuart F. J.; Brown, Patrick O.
- Journal of Structural Biology, Vol. 113, Issue 2