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Title: Beta-glucosidase I variants with improved properties

Abstract

The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.

Inventors:
; ; ; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
DANISCO US INC. Palo Alto, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1325778
Patent Number(s):
9447400
Application Number:
13/510,902
Assignee:
DANISCO US INC. (Palo Alto, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
FC36-08GO18078
Resource Type:
Patent
Resource Relation:
Patent File Date: 2010 Nov 19
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Bott, Richard R., Kaper, Thijs, Kelemen, Bradley, Goedegebuur, Frits, Hommes, Ronaldus Wilhelmus, Kralj, Slavko, Kruithof, Paulien, Nikolaev, Igor, Van Der Kley, Wilhelmus Antonious Hendricus, Van Lieshout, Johannes Franciscus Thomas, and Van Stigt Thans, Sander. Beta-glucosidase I variants with improved properties. United States: N. p., 2016. Web.
Bott, Richard R., Kaper, Thijs, Kelemen, Bradley, Goedegebuur, Frits, Hommes, Ronaldus Wilhelmus, Kralj, Slavko, Kruithof, Paulien, Nikolaev, Igor, Van Der Kley, Wilhelmus Antonious Hendricus, Van Lieshout, Johannes Franciscus Thomas, & Van Stigt Thans, Sander. Beta-glucosidase I variants with improved properties. United States.
Bott, Richard R., Kaper, Thijs, Kelemen, Bradley, Goedegebuur, Frits, Hommes, Ronaldus Wilhelmus, Kralj, Slavko, Kruithof, Paulien, Nikolaev, Igor, Van Der Kley, Wilhelmus Antonious Hendricus, Van Lieshout, Johannes Franciscus Thomas, and Van Stigt Thans, Sander. Tue . "Beta-glucosidase I variants with improved properties". United States. https://www.osti.gov/servlets/purl/1325778.
@article{osti_1325778,
title = {Beta-glucosidase I variants with improved properties},
author = {Bott, Richard R. and Kaper, Thijs and Kelemen, Bradley and Goedegebuur, Frits and Hommes, Ronaldus Wilhelmus and Kralj, Slavko and Kruithof, Paulien and Nikolaev, Igor and Van Der Kley, Wilhelmus Antonious Hendricus and Van Lieshout, Johannes Franciscus Thomas and Van Stigt Thans, Sander},
abstractNote = {The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {9}
}

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Works referenced in this record:

Fast identification of thermostable beta-glucosidase mutants on cellobiose by a novel combinatorial selection/screening approach
journal, August 2009


Crystal structure of intracellular family 1 β-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium
journal, March 2007


ACEII, a Novel Transcriptional Activator Involved in Regulation of Cellulase and Xylanase Genes of Trichoderma reesei
journal, April 2001


Separation of endo- and exo-type cellulases using a new affinity chromatography method
journal, April 1984


Outlook for cellulase improvement: Screening and selection strategies
journal, September 2006