skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Feruloyl-CoA:monolignol transferase

Abstract

The invention relates to nucleic acids encoding a feruloyl-CoA:monolignol transferase and the feruloyl-CoA:monolignol transferase enzyme that enables incorporation of monolignol ferulates, for example, including p-coumaryl ferulate, coniferyl ferulate, and sinapyl ferulate, into the lignin of plants.

Inventors:
; ; ;
Issue Date:
Research Org.:
WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1325010
Patent Number(s):
9,441,235
Application Number:
13/811,823
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, WI)
DOE Contract Number:  
FC02-07ER64494
Resource Type:
Patent
Resource Relation:
Patent File Date: 2011 Jul 22
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Wilkerson, Curtis, Ralph, John, Withers, Saunia, and Mansfield, Shawn D. Feruloyl-CoA:monolignol transferase. United States: N. p., 2016. Web.
Wilkerson, Curtis, Ralph, John, Withers, Saunia, & Mansfield, Shawn D. Feruloyl-CoA:monolignol transferase. United States.
Wilkerson, Curtis, Ralph, John, Withers, Saunia, and Mansfield, Shawn D. Tue . "Feruloyl-CoA:monolignol transferase". United States. https://www.osti.gov/servlets/purl/1325010.
@article{osti_1325010,
title = {Feruloyl-CoA:monolignol transferase},
author = {Wilkerson, Curtis and Ralph, John and Withers, Saunia and Mansfield, Shawn D.},
abstractNote = {The invention relates to nucleic acids encoding a feruloyl-CoA:monolignol transferase and the feruloyl-CoA:monolignol transferase enzyme that enables incorporation of monolignol ferulates, for example, including p-coumaryl ferulate, coniferyl ferulate, and sinapyl ferulate, into the lignin of plants.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {9}
}

Patent:

Save / Share:

Works referenced in this record:

Enzymatic Synthesis and Purification of Aromatic Coenzyme A Esters
journal, March 2002

  • Beuerle, Till; Pichersky, Eran
  • Analytical Biochemistry, Vol. 302, Issue 2, p. 305-312
  • DOI: 10.1006/abio.2001.5574

Coniferyl Ferulate Incorporation into Lignin Enhances the Alkaline Delignification and Enzymatic Degradation of Cell Walls
journal, September 2008

  • Grabber, John H.; Hatfield, Ronald D.; Lu, Fachuang
  • Biomacromolecules, Vol. 9, Issue 9, p. 2510-2516
  • DOI: 10.1021/bm800528f

Hydroxycinnamates in lignification
journal, August 2009


Advances in modifying lignin for enhanced biofuel production
journal, June 2010

  • Simmons, Blake A.; Loqué, Dominique; Ralph, John
  • Current Opinion in Plant Biology, Vol. 13, Issue 3, p. 312-319
  • DOI: 10.1016/j.pbi.2010.03.001

Optimization and Comparison of Five Methods for Extraction of Coniferyl Ferulate from Angelica sinensis
journal, January 2009


Lignin: Genetic Engineering and Impact on Pulping
journal, January 2003

  • Baucher, Marie; Halpin, Claire; Petit-Conil, Michel
  • Critical Reviews in Biochemistry and Molecular Biology, Vol. 38, Issue 4, p. 305-350
  • DOI: 10.1080/10409230391036757

Enzymatic Synthesis and Purification of Aromatic Coenzyme A Esters
journal, March 2002

  • Beuerle, Till; Pichersky, Eran
  • Analytical Biochemistry, Vol. 302, Issue 2, p. 305-312
  • DOI: 10.1006/abio.2001.5574

New method for quantitative determination of uronic acids
journal, August 1973


Highly Acylated (Acetylated and/or p-Coumaroylated) Native Lignins from Diverse Herbaceous Plants
journal, October 2008

  • del Río, José C.; Rencoret, Jorge; Marques, Gisela
  • Journal of Agricultural and Food Chemistry, Vol. 56, Issue 20, p. 9525-9534
  • DOI: 10.1021/jf800806h

Chemical composition and response to dilute-acid pretreatment and enzymatic saccharification of alfalfa, reed canarygrass, and switchgrass
journal, October 2006


Comparison of the Acetyl Bromide Spectrophotometric Method with Other Analytical Lignin Methods for Determining Lignin Concentration in Forage Samples
journal, June 2004

  • Fukushima, Romualdo S.; Hatfield, Ronald D.
  • Journal of Agricultural and Food Chemistry, Vol. 52, Issue 12, p. 3713-3720
  • DOI: 10.1021/jf035497l

p-coumaroylated syringyl units in maize lignin: Implications for β-ether cleavage by thioacidolysis
journal, December 1996


Apoplastic pH and Monolignol Addition Rate Effects on Lignin Formation and Cell Wall Degradability in Maize
journal, August 2003

  • Grabber, John H.; Hatfield, Ronald D.; Ralph, John
  • Journal of Agricultural and Food Chemistry, Vol. 51, Issue 17, p. 4984-4989
  • DOI: 10.1021/jf030027c

Coniferyl Ferulate Incorporation into Lignin Enhances the Alkaline Delignification and Enzymatic Degradation of Cell Walls
journal, September 2008

  • Grabber, John H.; Hatfield, Ronald D.; Lu, Fachuang
  • Biomacromolecules, Vol. 9, Issue 9, p. 2510-2516
  • DOI: 10.1021/bm800528f

Cross-Linking of Maize Walls by Ferulate Dimerization and Incorporation into Lignin
journal, December 2000

  • Grabber, John H.; Ralph, John; Hatfield, Ronald D.
  • Journal of Agricultural and Food Chemistry, Vol. 48, Issue 12, p. 6106-6113
  • DOI: 10.1021/jf0006978

Dehydrogenation Polymer−Cell Wall Complexes as a Model for Lignified Grass Walls
journal, January 1996

  • Grabber, John H.; Ralph, John; Hatfield, Ronald D.
  • Journal of Agricultural and Food Chemistry, Vol. 44, Issue 6, p. 1453-1459
  • DOI: 10.1021/jf9502717

Ferulate cross-linking in cell walls isolated from maize cell suspensions
journal, November 1995


Ferulate Cross-Links Limit the Enzymatic Degradation of Synthetically Lignified Primary Walls of Maize
journal, July 1998

  • Grabber, John H.; Ralph, John; Hatfield, Ronald D.
  • Journal of Agricultural and Food Chemistry, Vol. 46, Issue 7, p. 2609-2614
  • DOI: 10.1021/jf9800099

Formation of syringyl-rich lignins in maize as influenced by feruloylated xylans and p-coumaroylated monolignols
journal, April 2007


Model Studies of Ferulate−Coniferyl Alcohol Cross-Product Formation in Primary Maize Walls:  Implications for Lignification in Grasses
journal, October 2002

  • Grabber, John H.; Ralph, John; Hatfield, Ronald D.
  • Journal of Agricultural and Food Chemistry, Vol. 50, Issue 21, p. 6008-6016
  • DOI: 10.1021/jf0205312

Lignin-polysaccharide complexes of the plant cell wall and their effect on microbial degradation in the rumen
journal, October 1988


Monomeric and dimeric phenolic acids released from cell walls of grasses by sequential treatment with sodium hydroxide
journal, January 1991

  • Hartley, Roy D.; Morrison, W. Herbert
  • Journal of the Science of Food and Agriculture, Vol. 55, Issue 3, p. 365-375
  • DOI: 10.1002/jsfa.2740550305

Composition of cell walls isolated from cell types of grain sorghum stems
journal, May 1999


Degradation characteristics of isolated andin situ cell wall lucerne pectic polysaccharides by mixed ruminal microbes
journal, October 1995

  • Hatfield, R. D.; Weimer, P. J.
  • Journal of the Science of Food and Agriculture, Vol. 69, Issue 2, p. 185-196
  • DOI: 10.1002/jsfa.2740690208

Using the Acetyl Bromide Assay To Determine Lignin Concentrations in Herbaceous Plants:  Some Cautionary Notes
journal, February 1999

  • Hatfield, R. D.; Grabber, J.; Ralph, J.
  • Journal of Agricultural and Food Chemistry, Vol. 47, Issue 2, p. 628-632
  • DOI: 10.1021/jf9808776

A comparison of the insoluble residues produced by the Klason lignin and acid detergent lignin procedures
journal, May 1994

  • Hatfield, Ronald D.; Jung, Hans-Joachim G.; Ralph, John
  • Journal of the Science of Food and Agriculture, Vol. 65, Issue 1, p. 51-58
  • DOI: 10.1002/jsfa.2740650109

A potential role for sinapyl p-coumarate as a radical transfer mechanism in grass lignin formation
journal, July 2008


Synthesis of feruloylated and p-coumaroylated methyl glycosides
journal, May 1992


Lignocellulose biotechnology: issues of bioconversion and enzyme production
journal, December 2003

  • Howard, R. L.; Abotsi, E.; Jansen van Rensburg, E. L.
  • African Journal of Biotechnology, Vol. 2, Issue 12, p. 602-619
  • DOI: 10.5897/AJB2003.000-1115

Lignans from the wood of Aralia bipinnata
journal, July 1995


Solution-state 2D NMR of ball-milled plant cell wall gels in DMSO-d6/pyridine-d5
journal, January 2010

  • Kim, Hoon; Ralph, John
  • Org. Biomol. Chem., Vol. 8, Issue 3
  • DOI: 10.1039/B916070A

Time-Course Accumulation of Main Bioactive Components in the Rhizome of Ligusticum chuanxiong
journal, December 2006

  • Li, Song-Lin; Lin, Ge; Tam, Yun-Kau
  • Planta Medica, Vol. 72, Issue 3, p. 278-280
  • DOI: 10.1055/s-2005-916199

Detection and Determination of p-Coumaroylated Units in Lignins
journal, May 1999

  • Lu, Fachuang; Ralph, John
  • Journal of Agricultural and Food Chemistry, Vol. 47, Issue 5, p. 1988-1992
  • DOI: 10.1021/jf981140j

Facile Synthesis of 4-Hydroxycinnamyl p-Coumarates
journal, August 1998

  • Lu, Fachuang; Ralph, John
  • Journal of Agricultural and Food Chemistry, Vol. 46, Issue 8, p. 2911-2913
  • DOI: 10.1021/jf980440y

Highly Selective Syntheses of Coniferyl and Sinapyl Alcohols
journal, May 1998

  • Lu, Fachuang; Ralph, John
  • Journal of Agricultural and Food Chemistry, Vol. 46, Issue 5, p. 1794-1796
  • DOI: 10.1021/jf970953p

Novel tetrahydrofuran structures derived from β–β-coupling reactions involving sinapyl acetate in Kenaf lignins
journal, January 2008

  • Lu, Fachuang; Ralph, John
  • Organic & Biomolecular Chemistry, Vol. 6, Issue 20, p. 3681-3694
  • DOI: 10.1039/B809464K

Preliminary evidence for sinapyl acetate as a lignin monomer in kenaf
journal, December 2001

  • Lu, Fachuang; Ralph, John
  • Chemical Communications, Vol. 0, Issue 1, p. 90-91
  • DOI: 10.1039/B109876D

Size-exclusion chromatography of lignin as ion-pair complex
journal, March 1997


Modifications in Lignin and Accumulation of Phenolic Glucosides in Poplar Xylem upon Down-regulation of Caffeoyl-Coenzyme A O-Methyltransferase, an Enzyme Involved in Lignin Biosynthesis
journal, August 2000

  • Meyermans, Hugo; Morreel, Kris; Lapierre, Catherine
  • Journal of Biological Chemistry, Vol. 275, Issue 47, p. 36899-36909
  • DOI: 10.1074/jbc.M006915200

Optimization of Ammonia Fiber Expansion (AFEX) Pretreatment and Enzymatic Hydrolysis of Miscanthus x giganteus to Fermentable Sugars
journal, August 2007

  • Murnen, H. K.; Balan, V.; Chundawat, S. P. S.
  • Biotechnology Progress, Vol. 23, Issue 4
  • DOI: 10.1021/bp070098m