Colloidal-gold electrosensor measuring device

Title: Colloidal-gold electrosensor measuring device

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Abstract

The present invention provides a new device for use in measuring lead levels in biological and environmental samples. Using square wave coulometry and colloidal gold particles impregnated on carbon electrodes, the present invention provides a rapid, reliable, portable and inexpensive means of detecting low lead levels. The colloidal gold modified electrodes have microelectrode array characteristics and produce significantly higher stripping detection signals for lead than are produced at bulk gold electrode surfaces. The method is effective in determining levels of lead down to at least 5 {micro}g/dL in blood samples as small as 10 {micro}L. 9 figs.

Inventors:: Wegner, S; Harpold, M A; McCaffrey, T M; Morris, S E; Wojciechowski, M; Zhao, J; Henkens, R W; Naser, N; O`Daly, J P

Issue Date:: 1995-11-21

Research Org.:: ANDCARE Inc

OSTI Identifier:: 131930

Patent Number(s):: 5,468,366

Application Number:: PAN: 8-316,433

Assignee:: Andcare, Inc., Durham, NC (United States)

DOE Contract Number:: FG05-94ER81657

Resource Type:: Patent

Resource Relation:: Other Information: PBD: 21 Nov 1995

Country of Publication:: United States

Language:: English

Subject:: 54 ENVIRONMENTAL SCIENCES; 56 BIOLOGY AND MEDICINE, APPLIED STUDIES; LEAD; MEASURING METHODS; MEASURING INSTRUMENTS; DESIGN; BIOLOGICAL MATERIALS; ECOLOGICAL CONCENTRATION; PORTABLE EQUIPMENT; COLLOIDS; BIOLOGICAL ACCUMULATION

Citation Formats


                    Wegner, S, Harpold, M A, McCaffrey, T M, Morris, S E, Wojciechowski, M, Zhao, J, Henkens, R W, Naser, N, and O`Daly, J P. Colloidal-gold electrosensor measuring device.  United States: N. p., 1995. 
        Web.

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                    Wegner, S, Harpold, M A, McCaffrey, T M, Morris, S E, Wojciechowski, M, Zhao, J, Henkens, R W, Naser, N, & O`Daly, J P. Colloidal-gold electrosensor measuring device.  United States.

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                    Wegner, S, Harpold, M A, McCaffrey, T M, Morris, S E, Wojciechowski, M, Zhao, J, Henkens, R W, Naser, N, and O`Daly, J P. Tue .  
        "Colloidal-gold electrosensor measuring device".  United States.

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@article{osti_131930,

  title        = {Colloidal-gold electrosensor measuring device},

  author       = {Wegner, S and Harpold, M A and McCaffrey, T M and Morris, S E and Wojciechowski, M and Zhao, J and Henkens, R W and Naser, N and O`Daly, J P},

  abstractNote = {The present invention provides a new device for use in measuring lead levels in biological and environmental samples. Using square wave coulometry and colloidal gold particles impregnated on carbon electrodes, the present invention provides a rapid, reliable, portable and inexpensive means of detecting low lead levels. The colloidal gold modified electrodes have microelectrode array characteristics and produce significantly higher stripping detection signals for lead than are produced at bulk gold electrode surfaces. The method is effective in determining levels of lead down to at least 5 {micro}g/dL in blood samples as small as 10 {micro}L. 9 figs.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1995},

  month        = {11}

}

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