Increasing cell culture population doublings for long-term growth of finite life span human cell cultures
Abstract
Cell culture media formulations for culturing human epithelial cells are herein described. Also described are methods of increasing population doublings in a cell culture of finite life span human epithelial cells and prolonging the life span of human cell cultures. Using the cell culture media disclosed alone and in combination with addition to the cell culture of a compound associated with anti-stress activity achieves extended growth of pre-stasis cells and increased population doublings and life span in human epithelial cell cultures.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1259682
- Patent Number(s):
- 9,376,662
- Application Number:
- 14/627,888
- Assignee:
- The Regents of the University of California (Oakland, CA)
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2015 Feb 20
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES
Citation Formats
Stampfer, Martha R., and Garbe, James C. Increasing cell culture population doublings for long-term growth of finite life span human cell cultures. United States: N. p., 2016.
Web.
Stampfer, Martha R., & Garbe, James C. Increasing cell culture population doublings for long-term growth of finite life span human cell cultures. United States.
Stampfer, Martha R., and Garbe, James C. Tue .
"Increasing cell culture population doublings for long-term growth of finite life span human cell cultures". United States. https://www.osti.gov/servlets/purl/1259682.
@article{osti_1259682,
title = {Increasing cell culture population doublings for long-term growth of finite life span human cell cultures},
author = {Stampfer, Martha R. and Garbe, James C.},
abstractNote = {Cell culture media formulations for culturing human epithelial cells are herein described. Also described are methods of increasing population doublings in a cell culture of finite life span human epithelial cells and prolonging the life span of human cell cultures. Using the cell culture media disclosed alone and in combination with addition to the cell culture of a compound associated with anti-stress activity achieves extended growth of pre-stasis cells and increased population doublings and life span in human epithelial cell cultures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {6}
}
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