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Title: Fluidics platform and method for sample preparation

Abstract

Provided herein are fluidics platforms and related methods for performing integrated sample collection and solid-phase extraction of a target component of the sample all in one tube. The fluidics platform comprises a pump, particles for solid-phase extraction and a particle-holding means. The method comprises contacting the sample with one or more reagents in a pump, coupling a particle-holding means to the pump and expelling the waste out of the pump while the particle-holding means retains the particles inside the pump. The fluidics platform and methods herein described allow solid-phase extraction without pipetting and centrifugation.

Inventors:
;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1258015
Patent Number(s):
9,372,135
Application Number:
13/228,370
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2011 Sep 08
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Benner, Henry W., and Dzenitis, John M. Fluidics platform and method for sample preparation. United States: N. p., 2016. Web.
Benner, Henry W., & Dzenitis, John M. Fluidics platform and method for sample preparation. United States.
Benner, Henry W., and Dzenitis, John M. Tue . "Fluidics platform and method for sample preparation". United States. https://www.osti.gov/servlets/purl/1258015.
@article{osti_1258015,
title = {Fluidics platform and method for sample preparation},
author = {Benner, Henry W. and Dzenitis, John M.},
abstractNote = {Provided herein are fluidics platforms and related methods for performing integrated sample collection and solid-phase extraction of a target component of the sample all in one tube. The fluidics platform comprises a pump, particles for solid-phase extraction and a particle-holding means. The method comprises contacting the sample with one or more reagents in a pump, coupling a particle-holding means to the pump and expelling the waste out of the pump while the particle-holding means retains the particles inside the pump. The fluidics platform and methods herein described allow solid-phase extraction without pipetting and centrifugation.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {6}
}

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Works referenced in this record:

An integrated portable hand-held analyser for real-time isothermal nucleic acid amplification
journal, August 2007

  • Smith, Matthew C.; Steimle, George; Ivanov, Stan
  • Analytica Chimica Acta, Vol. 598, Issue 2, p. 286-294
  • DOI: 10.1016/j.aca.2007.07.036