Device, array, and methods for disease detection and analysis

Rao, Rupa S.; Lane, Stephen M.; Matthews, Dennis L.; Coleman, Matthew A.

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A - human necessities
A01 - agriculture
A21 - baking
A22 - butchering
A23 - foods or foodstuffs
A24 - tobacco
A41 - wearing apparel
A42 - headwear
A43 - footwear
A44 - haberdashery
A45 - hand or travelling articles
A46 - brushware
A47 - furniture
A61 - medical or veterinary science
A62 - life-saving
A63 - sports
A99 - subject matter not otherwise provided for in this section
B - performing operations
B01 - physical or chemical processes or apparatus in general
B02 - crushing, pulverising, or disintegrating
B03 - separation of solid materials using liquids or using pneumatic tables or jigs
B04 - centrifugal apparatus or machines for carrying-out physical or chemical processes
B05 - spraying or atomising in general
B06 - generating or transmitting mechanical vibrations in general
B07 - separating solids from solids
B08 - cleaning
B09 - disposal of solid waste
B21 - mechanical metal-working without essentially removing material
B22 - casting
B23 - machine tools
B24 - grinding
B25 - hand tools
B26 - hand cutting tools
B27 - working or preserving wood or similar material
B28 - working cement, clay, or stone
B29 - working of plastics
B30 - presses
B31 - making articles of paper, cardboard or material worked in a manner analogous to paper
B32 - layered products
B33 - additive manufacturing technology
B41 - printing
B42 - bookbinding
B43 - writing or drawing implements
B44 - decorative arts
B60 - vehicles in general
B61 - railways
B62 - land vehicles for travelling otherwise than on rails
B63 - ships or other waterborne vessels
B64 - aircraft
B65 - conveying
B66 - hoisting
B67 - opening, closing {or cleaning} bottles, jars or similar containers
B68 - saddlery
B81 - microstructural technology
B82 - nanotechnology
B99 - subject matter not otherwise provided for in this section
C - chemistry
C01 - inorganic chemistry
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C03 - glass
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C14 - skins
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C22 - metallurgy
C23 - coating metallic material
C25 - electrolytic or electrophoretic processes
C30 - crystal growth
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D - textiles
D01 - natural or man-made threads or fibres
D02 - yarns
D03 - weaving
D04 - braiding
D05 - sewing
D06 - treatment of textiles or the like
D07 - ropes
D10 - indexing scheme associated with sublasses of section d, relating to textiles
D21 - paper-making
D99 - subject matter not otherwise provided for in this section
E - fixed constructions
E01 - construction of roads, railways, or bridges
E02 - hydraulic engineering
E03 - water supply
E04 - building
E05 - locks
E06 - doors, windows, shutters, or roller blinds in general
E21 - earth drilling
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F - mechanical engineering
F01 - machines or engines in general
F02 - combustion engines
F03 - machines or engines for liquids
F04 - positive - displacement machines for liquids
F05 - indexing schemes relating to engines or pumps in various subclasses of classes f01-f04
F15 - fluid-pressure actuators
F16 - engineering elements and units
F17 - storing or distributing gases or liquids
F21 - lighting
F22 - steam generation
F23 - combustion apparatus
F24 - heating
F25 - refrigeration or cooling
F26 - drying
F27 - furnaces
F28 - heat exchange in general
F41 - weapons
F42 - ammunition
F99 - subject matter not otherwise provided for in this section
G - physics
G01 - measuring
G02 - optics
G03 - photography
G04 - horology
G05 - controlling
G06 - computing
G07 - checking-devices
G08 - signalling
G09 - education
G10 - musical instruments
G11 - information storage
G12 - instrument details
G16 - information and communication technology [ict] specially adapted for specific application fields
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H01 - basic electric elements
H02 - generation
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Y02 - technologies or applications for mitigation or adaptation against climate change
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Title: Device, array, and methods for disease detection and analysis

Inventors:: Rao, Rupa S.; Lane, Stephen M.; Matthews, Dennis L.; Coleman, Matthew A.

Issue Date:: 2016-06-14

Research Org.:: Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1257337

Patent Number(s):: 9366668

Application Number:: 14/465,796

Assignee:: Lawrence Livermore National Security, LLC (Livermore, CA)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY

C - CHEMISTRY C40 - COMBINATORIAL TECHNOLOGY C40B - COMBINATORIAL CHEMISTRY

Show more

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00621 - by physical means, e.g. trenches, raised areas
B01J2219/00385 - Printing
B01J2219/00626 - Covalent

C - CHEMISTRY C40 - COMBINATORIAL TECHNOLOGY C40B - COMBINATORIAL CHEMISTRY
C40B60/12 - for screening libraries

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00725 - Peptides
B01J2219/00612 - the surface being inorganic

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L3/50273 - {characterised by the means or forces applied to move the fluids

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/543 - with an insoluble carrier for immobilising immunochemicals

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00637 - by coating it with another layer

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L3/5025 - {for parallel transport of multiple samples}
B01L3/5027 - {by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00549 - 2-dimensional
B01J19/0046 - {Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides

Show less

DOE Contract Number:: AC52-07NA27344

Resource Type:: Patent

Resource Relation:: Patent File Date: 2014 Aug 21

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION; 60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats


                    Rao, Rupa S., Lane, Stephen M., Matthews, Dennis L., and Coleman, Matthew A. Device, array, and methods for disease detection and analysis.  United States: N. p., 2016. 
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                    Rao, Rupa S., Lane, Stephen M., Matthews, Dennis L., & Coleman, Matthew A. Device, array, and methods for disease detection and analysis.  United States.

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                    Rao, Rupa S., Lane, Stephen M., Matthews, Dennis L., and Coleman, Matthew A. Tue .  
        "Device, array, and methods for disease detection and analysis".  United States.  https://www.osti.gov/servlets/purl/1257337.

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@article{osti_1257337,

  title        = {Device, array, and methods for disease detection and analysis},

  author       = {Rao, Rupa S. and Lane, Stephen M. and Matthews, Dennis L. and Coleman, Matthew A.},

  abstractNote = {},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2016},

  month        = {6}

}

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Works referenced in this record:

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Simultaneous quantitative determination of multiple analytes with fluorescence‐tagged probes by Immunochromatography
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Biologic and therapeutic role of HER2 in cancer
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A mathematical model of lateral flow bioreactions applied to sandwich assays
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Comparison of Multiplexed Techniques for Detection of Bacterial and Viral Proteins
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Title: Device, array, and methods for disease detection and analysis

Citation Formats

Osteopontin Reduces Polyspermy During In Vitro Fertilization of Porcine Oocytes1 journal, November 2006

Simultaneous detection of the tumor suppressor FHIT gene and protein using the multi-functional biochip journal, November 2002

Identification of chromatin-related protein interactions using protein microarrays journal, November 2003

Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma journal, March 2005

A Microarray Immunoassay for Simultaneous Detection of Proteins and Bacteria journal, November 2002

Simultaneous Detection of Multiple Cytokines from Conditioned Media and Patient's Sera by an Antibody-Based Protein Array System journal, July 2001

Simultaneous quantitative determination of multiple analytes with fluorescence‐tagged probes by Immunochromatography journal, January 2003

Kinetics of antigen binding to antibody microspots: Strong limitation by mass transport to the surface journal, February 2006

Surface plasmon resonance for gas detection and biosensing journal, January 1983

Biologic and therapeutic role of HER2 in cancer journal, September 2003

A mathematical model of lateral flow bioreactions applied to sandwich assays journal, November 2003

Comparison of Multiplexed Techniques for Detection of Bacterial and Viral Proteins journal, August 2004

Use of Surface Plasmon Resonance to Probe the Equilibrium and Dynamic Aspects of Interactions Between Biological Macromolecules journal, June 1997

Measuring proteins on microarrays journal, February 2002

Serum levels of matrix metalloproteinase 2 in patients with breast cancer journal, November 2001

Simultaneous multianalysis for tumor markers by antibody fragments microarray system journal, May 2004

Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins journal, May 1991

Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay Based on Polyclonal Antibodies for the Detection of Polychlorinated Dibenzo- p -dioxins journal, March 1998

A Portable Array Biosensor for Detecting Multiple Analytes in Complex Samples journal, February 2004

A Computational Reaction−Diffusion Model for the Analysis of Transport-Limited Kinetics journal, December 1999

Genetic and epigenetic regulation of human breast cancer progression and metastasis journal, September 1998

Multiplex Measurement of Seven Tumor Markers Using an Electrochemical Protein Chip journal, September 2006

Modeling and Optimization of High-Sensitivity, Low-Volume Microfluidic-Based Surface Immunoassays journal, June 2005

Array biosensor for detection of toxins journal, October 2003

Abstract: Transparent conducting films journal, January 1976

Osteopontin Reduces Polyspermy During In Vitro Fertilization of Porcine Oocytes1
journal, November 2006

Simultaneous detection of the tumor suppressor FHIT gene and protein using the multi-functional biochip
journal, November 2002

Identification of chromatin-related protein interactions using protein microarrays
journal, November 2003

Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma
journal, March 2005

A Microarray Immunoassay for Simultaneous Detection of Proteins and Bacteria
journal, November 2002

Simultaneous Detection of Multiple Cytokines from Conditioned Media and Patient's Sera by an Antibody-Based Protein Array System
journal, July 2001

Simultaneous quantitative determination of multiple analytes with fluorescence‐tagged probes by Immunochromatography
journal, January 2003

Kinetics of antigen binding to antibody microspots: Strong limitation by mass transport to the surface
journal, February 2006

Surface plasmon resonance for gas detection and biosensing
journal, January 1983

Biologic and therapeutic role of HER2 in cancer
journal, September 2003

A mathematical model of lateral flow bioreactions applied to sandwich assays
journal, November 2003

Comparison of Multiplexed Techniques for Detection of Bacterial and Viral Proteins
journal, August 2004

Use of Surface Plasmon Resonance to Probe the Equilibrium and Dynamic Aspects of Interactions Between Biological Macromolecules
journal, June 1997

Measuring proteins on microarrays
journal, February 2002

Serum levels of matrix metalloproteinase 2 in patients with breast cancer
journal, November 2001

Simultaneous multianalysis for tumor markers by antibody fragments microarray system
journal, May 2004

Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins
journal, May 1991

Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay Based on Polyclonal Antibodies for the Detection of Polychlorinated Dibenzo- p -dioxins
journal, March 1998

A Portable Array Biosensor for Detecting Multiple Analytes in Complex Samples
journal, February 2004

A Computational Reaction−Diffusion Model for the Analysis of Transport-Limited Kinetics
journal, December 1999

Genetic and epigenetic regulation of human breast cancer progression and metastasis
journal, September 1998

Multiplex Measurement of Seven Tumor Markers Using an Electrochemical Protein Chip
journal, September 2006

Modeling and Optimization of High-Sensitivity, Low-Volume Microfluidic-Based Surface Immunoassays
journal, June 2005

Array biosensor for detection of toxins
journal, October 2003

Abstract: Transparent conducting films
journal, January 1976