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Title: Microfluidic ultrasonic particle separators with engineered node locations and geometries

An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream.
Inventors:
; ; ; ; ; ; ; ;
Issue Date:
OSTI Identifier:
1248912
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA) LLNL
Patent Number(s):
9,321,050
Application Number:
14/659,825
Contract Number:
AC52-07NA27344
Resource Relation:
Patent File Date: 2015 Mar 17
Research Org:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS

Works referenced in this record:

Multi-modal particle manipulator to enhance bead-based bioassays
journal, February 2010

Micro-manipulation of small particles by node position control of an ultrasonic standing wave
journal, May 2002