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Title: Methods of identification employing antibody profiles

Abstract

An identification method, applicable to the identification of animals or inanimate objects, is described. The method takes advantage of the set of individual-specific antibodies that are part of the unique antibody repertoire present in animals, by reacting an effective amount of such antibodies with a particular panel, of n-dimensional array (where n is typically one or two) consisting of an effective amount of many different antigens (typically greater than one thousand), to give antibody-antigen complexes. The profile or pattern formed by the antigen-antibody complexes, termed an antibody fingerprint, when revealed by an effective amount of an appropriate detector molecule, is uniquely representative of a particular individual. The method can similarly be used to distinguish genetically, or otherwise similar individuals, or their body parts containing individual-specific antibodies.

Inventors:
Issue Date:
Research Org.:
Dicor Technologies, Inc., Lake Forest, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1245990
Patent Number(s):
5270167
Application Number:
07/435,962
Assignee:
Dicor Technologies, Inc. (Lake Forest, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G - PHYSICS G07 - CHECKING-DEVICES G07D - HANDLING OF COINS OR VALUABLE PAPERS, e.g. TESTING, SORTING BY DENOMINATIONS, COUNTING, DISPENSING, CHANGING OR DEPOSITING
Resource Type:
Patent
Resource Relation:
Patent File Date: 1989 Nov 13
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Francoeur, Ann-Michele. Methods of identification employing antibody profiles. United States: N. p., 1993. Web.
Francoeur, Ann-Michele. Methods of identification employing antibody profiles. United States.
Francoeur, Ann-Michele. Tue . "Methods of identification employing antibody profiles". United States. https://www.osti.gov/servlets/purl/1245990.
@article{osti_1245990,
title = {Methods of identification employing antibody profiles},
author = {Francoeur, Ann-Michele},
abstractNote = {An identification method, applicable to the identification of animals or inanimate objects, is described. The method takes advantage of the set of individual-specific antibodies that are part of the unique antibody repertoire present in animals, by reacting an effective amount of such antibodies with a particular panel, of n-dimensional array (where n is typically one or two) consisting of an effective amount of many different antigens (typically greater than one thousand), to give antibody-antigen complexes. The profile or pattern formed by the antigen-antibody complexes, termed an antibody fingerprint, when revealed by an effective amount of an appropriate detector molecule, is uniquely representative of a particular individual. The method can similarly be used to distinguish genetically, or otherwise similar individuals, or their body parts containing individual-specific antibodies.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1993},
month = {12}
}

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Works referenced in this record:

Demographic study of a wild house sparrow population by DNA fingerprinting
journal, May 1987


Immunoblotting and dot immunobinding — Current status and outlook
journal, September 1984


Individual-specific ‘fingerprints’ of human DNA
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A highly polymorphic locus in human DNA.
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Positive identification of an immigration test-case using human DNA fingerprints
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Hypervariable ‘minisatellite’ regions in human DNA
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Antibody Fingerprinting: A Novel Method for Identifying Individual People and Animals
journal, July 1988


Forensic application of DNA ‘fingerprints’
journal, December 1985


Variable number of tandem repeat (VNTR) markers for human gene mapping
journal, March 1987