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Title: Photosynthetic microorganisms expressing thermostable lipase


The present invention encompasses a photosynthetic microorganism that produces biofuels and biofuel precursors.

Issue Date:
Research Org.:
The Arizona Board of Regents for and on Behalf of Arizona State University, Tempe, AZ (United States)
Sponsoring Org.:
OSTI Identifier:
Patent Number(s):
Application Number:
The Arizona Board of Regents for and on Behalf of Arizona State University (Tempe, AZ)
Patent Classifications (CPCs):
DOE Contract Number:  
Resource Type:
Resource Relation:
Patent File Date: 2013 May 20
Country of Publication:
United States

Citation Formats

Curtiss, Roy, and Liu, Xinyao. Photosynthetic microorganisms expressing thermostable lipase. United States: N. p., 2016. Web.
Curtiss, Roy, & Liu, Xinyao. Photosynthetic microorganisms expressing thermostable lipase. United States.
Curtiss, Roy, and Liu, Xinyao. Tue . "Photosynthetic microorganisms expressing thermostable lipase". United States.
title = {Photosynthetic microorganisms expressing thermostable lipase},
author = {Curtiss, Roy and Liu, Xinyao},
abstractNote = {The present invention encompasses a photosynthetic microorganism that produces biofuels and biofuel precursors.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {4}

Works referenced in this record:

Lipase protein engineering
journal, December 2000

CO2-limitation-inducible Green Recovery of fatty acids from cyanobacterial biomass
journal, April 2011

Nickel-inducible lysis system in Synechocystis sp. PCC 6803
journal, December 2009

Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunit
journal, January 1994

Influenza A (H5N1): Will It Be the Next Pandemic Influenza? Are We Ready?
journal, September 2005

Planning for Avian Influenza
journal, July 2006

DNA repair is more important than catalase for Salmonella virulence in mice.
journal, March 1995

Enteric Pathogens as Vaccine Vectors for Foreign Antigen Delivery
journal, September 2004

Characterization of recent H5 subtype avian influenza viruses from US poultry
journal, June 2004

Mechanism of araC autoregulation and the domains of two overlapping promoters, Pc and PBAD, in the L-arabinose regulatory region of Escherichia coli.
journal, February 1981

Trigger Factor Retards Protein Export in Escherichia coli
journal, August 2002

Th1-Directing Adjuvants Increase the Immunogenicity of Oligosaccharide-Protein Conjugate Vaccines Related to Streptococcus pneumoniae Type 3
journal, November 2003

Differential effect of auxotrophies on the release of macromolecules by Salmonella enterica vaccine strains
journal, December 2006

Amplification, expression, and packaging of a foreign gene by influenza virus
journal, December 1989

CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization
journal, March 2005

Complete genome sequence of Salmonella enterica serovar Typhimurium LT2
journal, October 2001

Bacteriophage T4 Genome
journal, March 2003

The annual impact of seasonal influenza in the US: Measuring disease burden and costs
journal, June 2007

Localization of RNA polymerases on influenza viral ribonucleoproteins by immunogold labeling
journal, June 1988

An improved reverse genetics system for influenza A virus generation and its implications for vaccine production
journal, November 2005

Generation of influenza A viruses entirely from cloned cDNAs
journal, August 1999

RNA Polymerase I-Mediated Expression of Influenza Viral RNA Molecules
journal, July 1994

Architecture of ribonucleoprotein complexes in influenza A virus particles
journal, January 2006

Contributions of Pneumolysin, Pneumococcal Surface Protein A (PspA), and PspC to Pathogenicity of Streptococcus pneumoniae D39 in a Mouse Model
journal, January 2007

Preparing for the Next Pandemic
journal, May 2005

Engineered viral vaccine constructs with dual specificity: Avian influenza and Newcastle disease
journal, May 2006

Th1 dominance in the immune response to live Salmonella typhimurium requires bacterial invasiveness but not persistence
journal, April 1999

The bacterial signal molecule, ppGpp, regulates Salmonella virulence gene expression
journal, May 2004

Salmonella enterica Serovar Typhimurium Invasion Is Repressed in the Presence of Bile
journal, December 2000

Attenuation of Equine Influenza Viruses through Truncations of the NS1 Protein
journal, June 2005

Serum Samples from Infants Vaccinated with a Pneumococcal Conjugate Vaccine, PncT, Protect Mice against Invasive Infection Caused by Streptococcus pneumoniae Serotypes 6A and 6B
journal, January 2001

Construction of self-disruptive Bacillus megaterium in response to substrate exhaustion for polyhydroxybutyrate production
journal, July 2002

Bacterial Meningitis in the United States in 1995
journal, October 1997

The Impact of Influenza Epidemics on Hospitalizations
journal, March 2000

SseL, a Salmonella deubiquitinase required for macrophage killing and virulence
journal, February 2007

The role of polyadenylation signal secondary structures on the resistance of plasmid vectors to nucleases
journal, May 2004

Distinct types of T-cell help for the induction of a humoral immune response to Streptococcus pneumoniae
journal, June 2001

The Role of relA and spoT in Yersinia pestis KIM5+ Pathogenicity
journal, August 2009

The Bacterial Signal Molecule, ppGpp, Mediates the Environmental Regulation of Both the Invasion and Intracellular Virulence Gene Programs of Salmonella
journal, August 2006

Epitope tagging of chromosomal genes in Salmonella
journal, December 2001

YERSINIA OUTER PROTEINS: Role in Modulation of Host Cell Signaling Responses and Pathogenesis
journal, October 2005

Biosynthesis and Assembly of Capsular Polysaccharides in Escherichia coli
journal, June 2006

Transcription Activation Parameters atara pBAD
journal, April 1996

Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity
journal, April 1997

PspA, a protection-eliciting pneumococcal protein: immunogenicity of isolated native PspA in mice
journal, June 1996

Antibacterial activity of Bacillus amyloliquefaciens phage endolysin without holin conjugation
journal, January 2001

Immunization with the C‐Domain of α‐Toxin Prevents Lethal Infection, Localizes Tissue Injury, and Promotes Host Response to Challenge with Clostridium perfringens
journal, August 2004

Genetic Loci of Major Antigenic Protein Genes of Edwardsiella tarda
journal, September 2005

Defining epitopes: It's not as easy as it seems
journal, October 1999

RpoS and RpoN are involved in the growth-dependent regulation of rfaH transcription and O antigen expression in Salmonella enterica serovar typhi
journal, January 2004

Salmonella Synthesizing 1-Monophosphorylated Lipopolysaccharide Exhibits Low Endotoxic Activity while Retaining Its Immunogenicity
journal, June 2011

Salmonella as Live Trojan Horse for Vaccine Development and Cancer Gene Therapy
journal, February 2010

Type 1/Type 2 Immunity in Infectious Diseases
journal, January 2001

Sequence of the Genome of Salmonella Bacteriophage P22
journal, November 2000

1918 Influenza: the Mother of All Pandemics
journal, January 2006

The PhoP/PhoQ two-component system stabilizes the alternative sigma factor RpoS in Salmonella enterica
journal, August 2006

Host and Bacterial Factors Contributing to the Clearance of Colonization by Streptococcus pneumoniae in a Murine Model
journal, October 2005

RNA polymerase I catalysed transcription of insert viral cDNA
journal, January 1993

Leucine-Responsive Regulatory Protein (Lrp) Acts as a Virulence Repressor in Salmonella enterica Serovar Typhimurium
journal, December 2008

Stabilization of recombinant avirulent vaccine strains in vivo
journal, September 1990

A Regulatory Cascade in the Induction of rhaBAD
journal, November 1993

Recombinant avirulent Salmonellae as oral vaccine carriers
journal, January 1992

Oral Immunization with Attenuated Salmonella Expressing Human Sperm Antigen Induces Antibodies in Serum and the Reproductive Tract1
journal, August 1995

A Regulated, NFκB-Assisted Import of Plasmid DNA into Mammalian Cell Nuclei
journal, May 2001

Yersinia pestis caf1 Variants and the Limits of Plague Vaccine Protection
journal, March 2008

Temperature has reciprocal effects on colanic acid and polysialic acid biosynthesis in E. coli K92
journal, January 2009

Salmonella enterica Serovar Typhimurium Strains with Regulated Delayed Attenuation In Vivo
journal, December 2008

Bacterial infectious disease control by vaccine development
journal, October 2002

Import of Plasmid DNA into the Nucleus Is Sequence Specific
journal, February 1997

Introduction of site-specific mutations into the genome of influenza virus.
journal, May 1990

The epidemiology of pneumococcal infection in children in the developing world
journal, April 1999

Incidence of Pneumococcal Disease Due to Non–Pneumococcal Conjugate Vaccine (PCV7) Serotypes in the United States during the Era of Widespread PCV7 Vaccination, 1998–2004
journal, November 2007

“Ambisense” Approach for the Generation of Influenza A Virus: vRNA and mRNA Synthesis from One Template
journal, February 2000

Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity.
journal, March 1995

Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae
journal, October 2000

Immune responses dependent on antigen location in recombinant attenuated Salmonella typhimurium vaccines following oral immunization
journal, July 2003

Transduction-Mediated Transfer of Unmarked Deletion and Point Mutations through Use of Counterselectable Suicide Vectors
journal, January 2002

Invertebrate connective tissue. Isolation of d-arabinose from sponge acidic polysaccharide
journal, August 1970

A Proteinaceous Gene Regulatory Thermometer in Salmonella
journal, July 1997

Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment
journal, July 2008

Evaluation of a phoP/phoQ-deleted, aroA-deleted live oral Salmonella typhi vaccine strain in human volunteers
journal, January 1996

Genome-Wide Screen of Salmonella Genes Expressed during Infection in Pigs, Using In Vivo Expression Technology
journal, October 2007

Allelic variation in the highly polymorphic locus pspC of Streptococcus pneumoniae
journal, February 2002

Expression of a Porphyromonas gingivalis hemagglutinin on the surface of a Salmonella vaccine vector
journal, January 2007

Effects of recJ, recQ, and recFOR Mutations on Recombination in Nuclease-Deficient recB recD Double Mutants of Escherichia coli
journal, February 2005

Impact of intracellular location of and antigen display by intracellular bacteria: implications for vaccine development
journal, January 1999

Immunogenicity and protective efficacy of DnaJ (hsp40) of Streptococcus pneumoniae against lethal infection in mice
journal, September 2006

Direct Transcriptional Control of the Plasminogen Activator Gene of Yersinia pestis by the Cyclic AMP Receptor Protein
journal, October 2007

Regulation of the l-arabinose transport operons in Escherichia coli
journal, September 1981

Salmonella -based vaccines for infectious diseases
journal, April 2007

Identification of a central regulator of stationary-phase gene expression in Escherichia coli
journal, January 1991

Regulation of L-arabinose transport in Salmonella typhimurium LT2
journal, March 1982

Surface-displayed viral antigens on Salmonella carrier vaccine
journal, June 2000

The lac repressor
journal, June 2005

AraC-DNA looping: Orientation and distance-dependent loop breaking by the cyclic AMP receptor protein
journal, March 1991

Bacteria-mediated DNA transfer in gene therapy and vaccination
journal, February 2004

Use of live bacterial vaccine vectors for antigen delivery: potential and limitations
journal, February 2001

Expression of the low calcium response in Yersinia pestis
journal, March 1989

Enhanced protective immunity against pneumococcal infection with PspA DNA and protein
journal, July 2006

Upstream operators enhance repression of the lac promoter
journal, August 1986

Repression oflacPromoter as a Function of Distance, Phase and Quality of an AuxiliarylacOperator
journal, March 1996

Lac repressor and Lac operator
journal, January 1976

Antigen Sampling Across Epithelial Barriers and Induction of Mucosal Immune Responses
journal, April 1996

High efficiency transformation of Salmonella typhimurium and Salmonella typhi by electroporation
journal, August 1990

Randomised trial of 23-valent pneumococcal capsular polysaccharide vaccine in prevention of pneumonia in middle-aged and elderly people
journal, February 1998

Temperature Regulation of the Hemin Storage (Hms+) Phenotype of Yersinia pestis Is Posttranscriptional
journal, March 2004

Bacterial virulence, proinflammatory cytokines and host immunity: how to choose the appropriate Salmonella vaccine strain?
journal, November 2001

Altered cotransduction frequencies exhibited by HT-mutants of Salmonella-phage P22
journal, January 1976

Phage P22-mutants with increased or decreased transduction abilities
journal, January 1972

Universal chemical assay for the detection and determination of siderophores
journal, January 1987

A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells
journal, February 1983

Development of Oral Vaccines to Stimulate Mucosal and Systemic Immunity: Barriers and Novel Strategies
journal, February 1995

Tightly regulated tac promoter vectors useful for the expression of unfused and fused proteins in Escherichia coli
journal, September 1988

The HD domain defines a new superfamily of metal-dependent phosphohydrolases
journal, December 1998

Breaking through the acid barrier: An orchestrated response to proton stress by enteric bacteria
journal, January 2001

Acyl carrier protein/SpoT interaction, the switch linking SpoT-dependent stress response to fatty acid metabolism
journal, November 2006

The Complete Genome Sequence of Escherichia coli K-12
journal, September 1997

The potential for using protein vaccines to protect against otitis media caused by Streptococcus pneumoniae
journal, December 2000

Salmonella redirects phagosomal maturation
journal, February 2004

Oral immunization using live attenuated Salmonella spp. as carriers of foreign antigens.
journal, July 1992

Simultaneous Analyses of Neutral Carbohydrates and Amino Sugars in Freshwaters with HPLC-PAD
journal, September 2003

The ACT domain family
journal, December 2001

Proteomic Characterization of Yersinia pestis Virulence
journal, November 2005

Nonrecombinant and recombinant avirulent Salmonella vaccines for poultry
journal, November 1996

Live oral avirulent Salmonella vaccines
journal, November 1993

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
journal, May 2000

Towards safer vectors for the field release of recombinant bacteria
journal, October 2002

Homocysteine Antagonism of Nitric Oxide-Related Cytostasis in Salmonella typhimurium
journal, April 1996

Induction of immunoglobulin synthesis by CD4+ T cell clones
journal, December 1993

Bacteriology of acute otitis media: A new perspective
journal, January 1992

Genome Sequence of Yersinia pestis KIM
journal, August 2002

DNA Uptake in Bacteria
journal, October 1999

Improved allelic exchange vectors and their use to analyze 987P fimbria gene expression
journal, January 1998

How Salmonella Survive Against the Odds
journal, October 1995

Can a ‘flawless’ live vector vaccine strain be engineered?
journal, August 2001

The Use of Live Attenuated Bacteria as a Delivery System for Heterologous Antigens
journal, January 2003

recB recJ mutants ofSalmonella typhimurium are deficient in transductional recombination, DNA repair and plasmid maintenance
journal, March 1996

The E. coli α-hemolysin secretion system and its use in vaccine development
journal, January 2002

Gastric Acidity and Cholera
journal, May 1973

Characterization of the Yersinia pestis Yfu ABC Inorganic Iron Transport System
journal, May 2001

TH1-TH2: a Procrustean paradigm
journal, June 2003

Functional gene transfer from intracellular bacteria to mammalian cells
journal, September 1998

Magnitude and Impact of Diarrheal Diseases
journal, July 2002

Mechanisms of bacterial resistance and response to bile
journal, July 2000