Capillary absorption spectrometer and process for isotopic analysis of small samples
Abstract
A capillary absorption spectrometer and process are described that provide highly sensitive and accurate stable absorption measurements of analytes in a sample gas that may include isotopologues of carbon and oxygen obtained from gas and biological samples. It further provides isotopic images of microbial communities that allow tracking of nutrients at the single cell level. It further targets naturally occurring variations in carbon and oxygen isotopes that avoids need for expensive isotopically labeled mixtures which allows study of samples taken from the field without modification. The method also permits sampling in vivo permitting real-time ambient studies of microbial communities.
- Inventors:
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1244233
- Patent Number(s):
- 9297756
- Application Number:
- 13/757,460
- Assignee:
- BATTELLE MEMORIAL INSTITUTE (Richland, WA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01J - MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC05-76RL01830
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2013 Feb 01
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION; 54 ENVIRONMENTAL SCIENCES; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Alexander, M. Lizabeth, Kelly, James F., Sams, Robert L., Moran, James J., Newburn, Matthew K., and Blake, Thomas A. Capillary absorption spectrometer and process for isotopic analysis of small samples. United States: N. p., 2016.
Web.
Alexander, M. Lizabeth, Kelly, James F., Sams, Robert L., Moran, James J., Newburn, Matthew K., & Blake, Thomas A. Capillary absorption spectrometer and process for isotopic analysis of small samples. United States.
Alexander, M. Lizabeth, Kelly, James F., Sams, Robert L., Moran, James J., Newburn, Matthew K., and Blake, Thomas A. Tue .
"Capillary absorption spectrometer and process for isotopic analysis of small samples". United States. https://www.osti.gov/servlets/purl/1244233.
@article{osti_1244233,
title = {Capillary absorption spectrometer and process for isotopic analysis of small samples},
author = {Alexander, M. Lizabeth and Kelly, James F. and Sams, Robert L. and Moran, James J. and Newburn, Matthew K. and Blake, Thomas A.},
abstractNote = {A capillary absorption spectrometer and process are described that provide highly sensitive and accurate stable absorption measurements of analytes in a sample gas that may include isotopologues of carbon and oxygen obtained from gas and biological samples. It further provides isotopic images of microbial communities that allow tracking of nutrients at the single cell level. It further targets naturally occurring variations in carbon and oxygen isotopes that avoids need for expensive isotopically labeled mixtures which allows study of samples taken from the field without modification. The method also permits sampling in vivo permitting real-time ambient studies of microbial communities.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 29 00:00:00 EDT 2016},
month = {Tue Mar 29 00:00:00 EDT 2016}
}
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Works referenced in this record:
Laser ablation-combustion-GC-IRMS--a new method for online analysis of intra-annual variation of 13C in tree rings
journal, November 2004
- Schulze, B.; Wirth, C.; Linke, P.
- Tree Physiology, Vol. 24, Issue 11
Laser ablation isotope ratio mass spectrometry for enhanced sensitivity and spatial resolution in stable isotope analysis: LA-IRMS for enhanced sensitivity in stable isotope analysis
journal, April 2011
- Moran, James J.; Newburn, Matt K.; Alexander, M. Lizabeth
- Rapid Communications in Mass Spectrometry, Vol. 25, Issue 9
New method for isotopic ratio measurements of atmospheric carbon dioxide using a 4.3 μm pulsed quantum cascade laser
journal, January 2008
- Nelson, D. D.; McManus, J. B.; Herndon, S. C.
- Applied Physics B, Vol. 90, Issue 2
Absorption spectroscopy in hollow-glass waveguides using infrared diode lasers
conference, September 2002
- Blake, Thomas A.; Kelly, James F.; Stewart, Timothy L.
- International Symposium on Optical Science and Technology, SPIE Proceedings
High-precision optical measurements of 13C/12C isotope ratios in organic compounds at natural abundance
journal, June 2009
- Zare, R. N.; Kuramoto, D. S.; Haase, C.
- Proceedings of the National Academy of Sciences, Vol. 106, Issue 27, p. 10928-10932
A capillary absorption spectrometer for stable carbon isotope ratio (13C/12C) analysis in very small samples
journal, February 2012
- Kelly, J. F.; Sams, R. L.; Blake, T. A.
- Review of Scientific Instruments, Vol. 83, Issue 2, Article No. 023101
Systems and methods for monitoring relative concentrations of different isotopic forms of a chemical species
patent, September 1999
- Micheels, Ronald H.; Kaunitz, Jonathan D.
- US Patent Document 5,957,858