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Title: Butanol tolerance in microorganisms

Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from a pyruvate utilizing pathway. Yeast host cells provided herein comprise reduced pyruvate decarboxylase activity and modified adenylate cyclase activity. In embodiments, yeast host cells provided herein comprise resistance to butanol and increased biomass production.
Inventors:
;
Issue Date:
OSTI Identifier:
1241024
Assignee:
Butamax Advanced Biofuels LLC (Wilmington, DE) ARPA-E
Patent Number(s):
9,273,330
Application Number:
14/045,506
Contract Number:
AR0000006
Resource Relation:
Patent File Date: 2013 Oct 03
Research Org:
Butamax Advanced Biofuels LLC, Wilmington, DE (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES

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