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Title: Butanol tolerance in microorganisms

Abstract

Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from a pyruvate utilizing pathway. Yeast host cells provided herein comprise reduced pyruvate decarboxylase activity and modified adenylate cyclase activity. In embodiments, yeast host cells provided herein comprise resistance to butanol and increased biomass production.

Inventors:
;
Issue Date:
Research Org.:
Butamax Advanced Biofuels LLC, Wilmington, DE (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1241024
Patent Number(s):
9273330
Application Number:
14/045,506
Assignee:
Butamax Advanced Biofuels LLC (Wilmington, DE)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
DOE Contract Number:  
AR0000006
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 Oct 03
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Bramucci, Michael G., and Nagarajan, Vasantha. Butanol tolerance in microorganisms. United States: N. p., 2016. Web.
Bramucci, Michael G., & Nagarajan, Vasantha. Butanol tolerance in microorganisms. United States.
Bramucci, Michael G., and Nagarajan, Vasantha. Tue . "Butanol tolerance in microorganisms". United States. https://www.osti.gov/servlets/purl/1241024.
@article{osti_1241024,
title = {Butanol tolerance in microorganisms},
author = {Bramucci, Michael G. and Nagarajan, Vasantha},
abstractNote = {Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from a pyruvate utilizing pathway. Yeast host cells provided herein comprise reduced pyruvate decarboxylase activity and modified adenylate cyclase activity. In embodiments, yeast host cells provided herein comprise resistance to butanol and increased biomass production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {3}
}

Patent:

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