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Title: Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography

Abstract

Techniques for nanoflow serial femtosecond x-ray protein crystallography include providing a sample fluid by mixing a plurality of a first target of interest with a carrier fluid and injecting the sample fluid into a vacuum chamber at a rate less than about 4 microliters per minute. In some embodiments, the carrier fluid has a viscosity greater than about 3 centipoise.

Inventors:
; ;
Issue Date:
Research Org.:
SLAC National Accelerator Lab., Menlo Park, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1240690
Patent Number(s):
9,275,844
Application Number:
13/896,303
Assignee:
The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
DOE Contract Number:  
AC02-76SF00515
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 May 16
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE

Citation Formats

Bogan, Michael J., Laksmono, Hartawan, and Sierra, Raymond G. Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography. United States: N. p., 2016. Web.
Bogan, Michael J., Laksmono, Hartawan, & Sierra, Raymond G. Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography. United States.
Bogan, Michael J., Laksmono, Hartawan, and Sierra, Raymond G. Tue . "Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography". United States. https://www.osti.gov/servlets/purl/1240690.
@article{osti_1240690,
title = {Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography},
author = {Bogan, Michael J. and Laksmono, Hartawan and Sierra, Raymond G.},
abstractNote = {Techniques for nanoflow serial femtosecond x-ray protein crystallography include providing a sample fluid by mixing a plurality of a first target of interest with a carrier fluid and injecting the sample fluid into a vacuum chamber at a rate less than about 4 microliters per minute. In some embodiments, the carrier fluid has a viscosity greater than about 3 centipoise.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {3}
}

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