Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography
Abstract
Techniques for nanoflow serial femtosecond x-ray protein crystallography include providing a sample fluid by mixing a plurality of a first target of interest with a carrier fluid and injecting the sample fluid into a vacuum chamber at a rate less than about 4 microliters per minute. In some embodiments, the carrier fluid has a viscosity greater than about 3 centipoise.
- Inventors:
- Issue Date:
- Research Org.:
- SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1240690
- Patent Number(s):
- 9275844
- Application Number:
- 13/896,303
- Assignee:
- The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC02-76SF00515
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2013 May 16
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 36 MATERIALS SCIENCE
Citation Formats
Bogan, Michael J., Laksmono, Hartawan, and Sierra, Raymond G. Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography. United States: N. p., 2016.
Web.
Bogan, Michael J., Laksmono, Hartawan, & Sierra, Raymond G. Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography. United States.
Bogan, Michael J., Laksmono, Hartawan, and Sierra, Raymond G. Tue .
"Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography". United States. https://www.osti.gov/servlets/purl/1240690.
@article{osti_1240690,
title = {Apparatus and method for nanoflow liquid jet and serial femtosecond x-ray protein crystallography},
author = {Bogan, Michael J. and Laksmono, Hartawan and Sierra, Raymond G.},
abstractNote = {Techniques for nanoflow serial femtosecond x-ray protein crystallography include providing a sample fluid by mixing a plurality of a first target of interest with a carrier fluid and injecting the sample fluid into a vacuum chamber at a rate less than about 4 microliters per minute. In some embodiments, the carrier fluid has a viscosity greater than about 3 centipoise.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {3}
}
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