DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Monodisperse microdroplet generation and stopping without coalescence

Abstract

A system for monodispersed microdroplet generation and trapping including providing a flow channel in a microchip; producing microdroplets in the flow channel, the microdroplets movable in the flow channel; providing carrier fluid in the flow channel using a pump or pressure source; controlling movement of the microdroplets in the flow channel and trapping the microdroplets in a desired location in the flow channel. The system includes a microchip; a flow channel in the microchip; a droplet maker that generates microdroplets, the droplet maker connected to the flow channel; a carrier fluid in the flow channel, the carrier fluid introduced to the flow channel by a source of carrier fluid, the source of carrier fluid including a pump or pressure source; a valve connected to the carrier fluid that controls flow of the carrier fluid and enables trapping of the microdroplets.

Inventors:
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1239825
Patent Number(s):
9266107
Application Number:
14/662,535
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
G - PHYSICS G05 - CONTROLLING G05D - SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Mar 19
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 42 ENGINEERING; 60 APPLIED LIFE SCIENCES

Citation Formats

Beer, Neil Reginald. Monodisperse microdroplet generation and stopping without coalescence. United States: N. p., 2016. Web.
Beer, Neil Reginald. Monodisperse microdroplet generation and stopping without coalescence. United States.
Beer, Neil Reginald. Tue . "Monodisperse microdroplet generation and stopping without coalescence". United States. https://www.osti.gov/servlets/purl/1239825.
@article{osti_1239825,
title = {Monodisperse microdroplet generation and stopping without coalescence},
author = {Beer, Neil Reginald},
abstractNote = {A system for monodispersed microdroplet generation and trapping including providing a flow channel in a microchip; producing microdroplets in the flow channel, the microdroplets movable in the flow channel; providing carrier fluid in the flow channel using a pump or pressure source; controlling movement of the microdroplets in the flow channel and trapping the microdroplets in a desired location in the flow channel. The system includes a microchip; a flow channel in the microchip; a droplet maker that generates microdroplets, the droplet maker connected to the flow channel; a carrier fluid in the flow channel, the carrier fluid introduced to the flow channel by a source of carrier fluid, the source of carrier fluid including a pump or pressure source; a valve connected to the carrier fluid that controls flow of the carrier fluid and enables trapping of the microdroplets.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {2}
}

Works referenced in this record:

Monodisperse droplet generation and rapid trapping for single molecule detection and reaction kinetics measurement
journal, January 2009


Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
patent-application, July 2008