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Title: Hydrogenase polypeptide and methods of use

Abstract

Provided herein are polypeptides having hydrogenase activity. The polypeptide may be multimeric, and may have hydrogenase activity of at least 0.05 micromoles H.sub.2 produced min.sup.-1 mg protein.sup.-1. Also provided herein are polynucleotides encoding the polypeptides, genetically modified microbes that include polynucleotides encoding one or more subunits of the multimeric polypeptide, and methods for making and using the polypeptides.

Inventors:
; ; ;
Issue Date:
Research Org.:
Univ. of Georgia, Athens, GA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1237279
Patent Number(s):
9249440
Application Number:
14/204,802
Assignee:
University of Georgia Research Foundation, Inc.
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
FG02-05ER15710
Resource Type:
Patent
Resource Relation:
Patent File Date: 2014 Mar 11
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; 08 HYDROGEN

Citation Formats

Adams, Michael W.W., Hopkins, Robert C., Jenney, JR, Francis E., and Sun, Junsong. Hydrogenase polypeptide and methods of use. United States: N. p., 2016. Web.
Adams, Michael W.W., Hopkins, Robert C., Jenney, JR, Francis E., & Sun, Junsong. Hydrogenase polypeptide and methods of use. United States.
Adams, Michael W.W., Hopkins, Robert C., Jenney, JR, Francis E., and Sun, Junsong. Tue . "Hydrogenase polypeptide and methods of use". United States. https://www.osti.gov/servlets/purl/1237279.
@article{osti_1237279,
title = {Hydrogenase polypeptide and methods of use},
author = {Adams, Michael W.W. and Hopkins, Robert C. and Jenney, JR, Francis E. and Sun, Junsong},
abstractNote = {Provided herein are polypeptides having hydrogenase activity. The polypeptide may be multimeric, and may have hydrogenase activity of at least 0.05 micromoles H.sub.2 produced min.sup.-1 mg protein.sup.-1. Also provided herein are polynucleotides encoding the polypeptides, genetically modified microbes that include polynucleotides encoding one or more subunits of the multimeric polypeptide, and methods for making and using the polypeptides.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {2}
}

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