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Title: Host cells and methods for producing isoprenyl alkanoates

Abstract

The invention provides for a method of producing an isoprenyl alkanoate in a genetically modified host cell. In one embodiment, the method comprises culturing a genetically modified host cell which expresses an enzyme capable of catalyzing the esterification of an isoprenol and a straight-chain fatty acid, such as an alcohol acetyltransferase (AAT), wax ester synthase/diacylglycerol acyltransferase (WS/DGAT) or lipase, under a suitable condition so that the isoprenyl alkanoate is produced.

Inventors:
; ;
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1227365
Patent Number(s):
9200298
Application Number:
12/644,531
Assignee:
The Regents of the University of California
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2009 Dec 22
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Lee, Taek Soon, Fortman, Jeffrey L., and Keasling, Jay D. Host cells and methods for producing isoprenyl alkanoates. United States: N. p., 2015. Web.
Lee, Taek Soon, Fortman, Jeffrey L., & Keasling, Jay D. Host cells and methods for producing isoprenyl alkanoates. United States.
Lee, Taek Soon, Fortman, Jeffrey L., and Keasling, Jay D. Tue . "Host cells and methods for producing isoprenyl alkanoates". United States. https://www.osti.gov/servlets/purl/1227365.
@article{osti_1227365,
title = {Host cells and methods for producing isoprenyl alkanoates},
author = {Lee, Taek Soon and Fortman, Jeffrey L. and Keasling, Jay D.},
abstractNote = {The invention provides for a method of producing an isoprenyl alkanoate in a genetically modified host cell. In one embodiment, the method comprises culturing a genetically modified host cell which expresses an enzyme capable of catalyzing the esterification of an isoprenol and a straight-chain fatty acid, such as an alcohol acetyltransferase (AAT), wax ester synthase/diacylglycerol acyltransferase (WS/DGAT) or lipase, under a suitable condition so that the isoprenyl alkanoate is produced.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2015},
month = {12}
}

Patent:

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