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Title: L-malate production by metabolically engineered escherichia coli

Abstract

A process for the production of malic acid in commercially significant quantities from the carbon compounds by genetically modified bacterial strains (GMBS; also referred to as biocatalysts or genetically modified microorganisms) is disclosed. Microorganisms suitable for the production of malic acid can be cultured in one or two-step processes as disclosed herein.

Inventors:
; ; ;
Issue Date:
Research Org.:
Univ. of Florida, Gainesville, FL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1226538
Patent Number(s):
9187772
Application Number:
13/819,773
Assignee:
University of Florida Research Foundation, Inc. (Gainesville, FL)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
FG36-08GO88142
Resource Type:
Patent
Resource Relation:
Patent File Date: 2011 Sep 01
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Zhang, Xueli, Wang, Xuan, Shanmugam, Keelnatham T., and Ingram, Lonnie O'Neal. L-malate production by metabolically engineered escherichia coli. United States: N. p., 2015. Web.
Zhang, Xueli, Wang, Xuan, Shanmugam, Keelnatham T., & Ingram, Lonnie O'Neal. L-malate production by metabolically engineered escherichia coli. United States.
Zhang, Xueli, Wang, Xuan, Shanmugam, Keelnatham T., and Ingram, Lonnie O'Neal. Tue . "L-malate production by metabolically engineered escherichia coli". United States. https://www.osti.gov/servlets/purl/1226538.
@article{osti_1226538,
title = {L-malate production by metabolically engineered escherichia coli},
author = {Zhang, Xueli and Wang, Xuan and Shanmugam, Keelnatham T. and Ingram, Lonnie O'Neal},
abstractNote = {A process for the production of malic acid in commercially significant quantities from the carbon compounds by genetically modified bacterial strains (GMBS; also referred to as biocatalysts or genetically modified microorganisms) is disclosed. Microorganisms suitable for the production of malic acid can be cultured in one or two-step processes as disclosed herein.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2015},
month = {11}
}

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Works referenced in this record:

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