Modular microfluidic system for biological sample preparation
Abstract
A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1221984
- Patent Number(s):
- 9144799
- Application Number:
- 12/943,677
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B - PERFORMING OPERATIONS B03 - SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS B03C - MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS
- DOE Contract Number:
- AC52-07NA27344
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2010 Nov 10
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Rose, Klint A., Mariella, Jr., Raymond P., Bailey, Christopher G., and Ness, Kevin Dean. Modular microfluidic system for biological sample preparation. United States: N. p., 2015.
Web.
Rose, Klint A., Mariella, Jr., Raymond P., Bailey, Christopher G., & Ness, Kevin Dean. Modular microfluidic system for biological sample preparation. United States.
Rose, Klint A., Mariella, Jr., Raymond P., Bailey, Christopher G., and Ness, Kevin Dean. Tue .
"Modular microfluidic system for biological sample preparation". United States. https://www.osti.gov/servlets/purl/1221984.
@article{osti_1221984,
title = {Modular microfluidic system for biological sample preparation},
author = {Rose, Klint A. and Mariella, Jr., Raymond P. and Bailey, Christopher G. and Ness, Kevin Dean},
abstractNote = {A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 29 00:00:00 EDT 2015},
month = {Tue Sep 29 00:00:00 EDT 2015}
}
Works referenced in this record:
Microfluidic DNA sample preparation method and device
patent, March 2002
- Krulevitch, Peter; Miles, Robin R.; Wang, Xiao-Bo
- US Patent Document 6,352,838
Three dimensional separation trap based on dielectrophoresis and use thereof
patent, May 2004
- Mariella, Jr., Raymond P.
- US Patent Document 6,730,204
Multi-stage separations based on dielectrophoresis
patent, July 2004
- Mariella, Jr., Raymond P.
- US Patent Document 6,761,811
Sample preparation: the weak link in microfluidics-based biodetection
journal, May 2008
- Mariella, Raymond
- Biomedical Microdevices, Vol. 10, Issue 6