DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Modular microfluidic system for biological sample preparation

Abstract

A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.

Inventors:
; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1221984
Patent Number(s):
9144799
Application Number:
12/943,677
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B - PERFORMING OPERATIONS B03 - SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS B03C - MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2010 Nov 10
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Rose, Klint A., Mariella, Jr., Raymond P., Bailey, Christopher G., and Ness, Kevin Dean. Modular microfluidic system for biological sample preparation. United States: N. p., 2015. Web.
Rose, Klint A., Mariella, Jr., Raymond P., Bailey, Christopher G., & Ness, Kevin Dean. Modular microfluidic system for biological sample preparation. United States.
Rose, Klint A., Mariella, Jr., Raymond P., Bailey, Christopher G., and Ness, Kevin Dean. Tue . "Modular microfluidic system for biological sample preparation". United States. https://www.osti.gov/servlets/purl/1221984.
@article{osti_1221984,
title = {Modular microfluidic system for biological sample preparation},
author = {Rose, Klint A. and Mariella, Jr., Raymond P. and Bailey, Christopher G. and Ness, Kevin Dean},
abstractNote = {A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 29 00:00:00 EDT 2015},
month = {Tue Sep 29 00:00:00 EDT 2015}
}

Works referenced in this record:

Microfluidic DNA sample preparation method and device
patent, March 2002


Multi-stage separations based on dielectrophoresis
patent, July 2004


Sample preparation: the weak link in microfluidics-based biodetection
journal, May 2008