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Title: Accurate and rapid micromixer for integrated microfluidic devices

The invention may provide a microfluidic mixer having a droplet generator and a droplet mixer in selective fluid connection with the droplet generator. The droplet generator comprises first and second fluid chambers that are structured to be filled with respective first and second fluids that can each be held in isolation for a selectable period of time. The first and second fluid chambers are further structured to be reconfigured into a single combined chamber to allow the first and second fluids in the first and second fluid chambers to come into fluid contact with each other in the combined chamber for a selectable period of time prior to being brought into the droplet mixer.
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Issue Date:
OSTI Identifier:
The Regents of the University of California (Oakland, CA) CHO
Patent Number(s):
Application Number:
Contract Number:
Resource Relation:
Patent File Date: 2009 Jan 21
Research Org:
The Regents of the University of California, Oakland, CA (United States)
Sponsoring Org:
Country of Publication:
United States

Works referenced in this record:

Micromixers—a review on passive and active mixing principles
journal, April 2005
  • Hessel, Volker; Löwe, Holger; Schönfeld, Friedhelm
  • Chemical Engineering Science, Vol. 60, Issue 8-9, p. 2479-2501
  • DOI: 10.1016/j.ces.2004.11.033

Reactions in Droplets in Microfluidic Channels
journal, November 2006
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Effects of viscosity on droplet formation and mixing in microfluidic channels
journal, April 2004
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  • DOI: 10.1016/j.aca.2003.11.024

From The Cover: Systematic investigation of protein phase behavior with a microfluidic formulator
journal, September 2004
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  • DOI: 10.1073/pnas.0405847101