Global to push GA events into
skip to main content

Title: Dendrimers and methods of preparing same through proportionate branching

The present invention provides for monodispersed dendrimers having a core, branches and periphery ends, wherein the number of branches increases exponentially from the core to the periphery end and the length of the branches increases exponentially from the periphery end to the core, thereby providing for attachment of chemical species at the periphery ends without exhibiting steric hindrance.
  1. (Bruce)
Issue Date:
OSTI Identifier:
University of Maryland, Baltimore (Baltimore, MD) CHO
Patent Number(s):
Application Number:
Contract Number:
Resource Relation:
Patent File Date: 2013 Jan 29
Research Org:
University of Maryland Baltimore, Baltimore, MD (United States)
Sponsoring Org:
Country of Publication:
United States

Works referenced in this record:

Synthesis and relaxometry of high-generation (G = 5, 7, 9, and 10) PAMAM dendrimer-DOTA-gadolinium chelates
journal, February 1999

Fluorinated dendrimers
journal, August 2003

Self-assembly of pH-responsive fluorinated dendrimer-based particulates for drug delivery and noninvasive imaging
journal, August 2009

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering
journal, January 2009
  • Franke, Daniel; Svergun, Dmitri I.
  • Journal of Applied Crystallography, Vol. 42, Issue 2, p. 342-346
  • DOI: 10.1107/S0021889809000338

The design and synthesis of highly branched and spherically symmetric fluorinated oils and amphiles
journal, May 2007

Symmetry-Guided Design and Fluorous Synthesis of a Stable and Rapidly Excreted Imaging Tracer for 19F MRI
journal, June 2009
  • Jiang, Zhong-Xing; Liu, Xin; Jeong, Eun-Kee
  • Angewandte Chemie International Edition, Vol. 48, Issue 26, p. 4755-4758
  • DOI: 10.1002/anie.200901005

PRIMUS: a Windows PC-based system for small-angle scattering data analysis
journal, September 2003
  • Konarev, Petr V.; Volkov, Vladimir V.; Sokolova, Anna V.
  • Journal of Applied Crystallography, Vol. 36, Issue 5, p. 1277-1282
  • DOI: 10.1107/S0021889803012779

Automated matching of high- and low-resolution structural models
journal, February 2001

Controlling polymer shape through the self-assembly of dendritic side-groups
journal, January 1998
  • Percec, V.; Ahn, C.-H.; Ungar, G.
  • Nature, Vol. 391, Issue 6663, p. 161-164
  • DOI: 10.1038/34384

Determination of the regularization parameter in indirect-transform methods using perceptual criteria
journal, August 1992

Novel generation ponytails in fluorous chemistry: Syntheses of primary, secondary, and tertiary (nonafluoro-tert-butyloxy)ethyl amines
journal, November 2006
  • Szabó, Dénes; Mohl, János; Bálint, Ana-Maria
  • Journal of Fluorine Chemistry, Vol. 127, Issue 11, p. 1496-1504
  • DOI: 10.1016/j.jfluchem.2006.06.020

Uniqueness of ab initio shape determination in small-angle scattering
journal, April 2003
  • Volkov, Vladimir V.; Svergun, Dmitri I.
  • Journal of Applied Crystallography, Vol. 36, Issue 3, p. 860-864
  • DOI: 10.1107/S0021889803000268

Rapid Construction of Large-size Phenylacetylene Dendrimers up to 12.5 Nanometers in Molecular Diameter
journal, September 1993
  • Xu, Zhifu; Moore, Jeffrey S.
  • Angewandte Chemie International Edition in English, Vol. 32, Issue 9, p. 1354-1357
  • DOI: 10.1002/anie.199313541