Celluloytic enzymes, nucleic acids encoding them and methods for making and using them

Title: Celluloytic enzymes, nucleic acids encoding them and methods for making and using them

The invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, .beta.-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention.

Inventors:: Gray, Kevin A.; Zhao, Lishan; Cayouette, Michelle H.

Issue Date:: 2015-09-08

OSTI Identifier:: 1214148

Assignee:: BP Corporation North America Inc. (Houston, TX) GFO

Patent Number(s):: 9,127,263

Application Number:: 13/354,503

Contract Number:: FC36-03GO13146

Resource Relation:: Patent File Date: 2012 Jan 20

Research Org:: BP Corporation North America Inc., Houston, TX (United States)

Sponsoring Org:: USDOE

Country of Publication:: United States

Language:: English

Full Text
View Full Text

Have feedback or suggestions for a way to improve these results? !

Save / Share this Record no
Export Metadata
- Endnote
- RIS
- Excel
- CSV
- XML
Send to Email

Send to Email

Email address:

Content:

Works referenced in this record:

Basic local alignment search tool
journal, October 1990

Altschul, Stephen F.; Gish, Warren; Miller, Webb
Journal of Molecular Biology, Vol. 215, Issue 3, p. 403-410
DOI: 10.1016/S0022-2836(05)80360-2

Biotechnological applications of phage and cell display
journal, February 2001

Benhar, Itai
Biotechnology Advances, Vol. 19, Issue 1, p. 1-33
DOI: 10.1016/S0734-9750(00)00054-9

Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids
journal, November 1998

Broun, Pierre; Shanklin, John; Whittle, Ed
Science, Vol. 282, Issue 5392, p. 1315-1317
DOI: 10.1126/science.282.5392.1315

Practical limits of function prediction
journal, January 2000

Devos, Damien; Valencia, Alfonso
Proteins: Structure, Function, and Genetics, Vol. 41, Issue 1, p. 98-107
DOI: 10.1002/1097-0134(20001001)41:1<98::AID-PROT120>3.0.CO;2-S

Protein tolerance to random amino acid change
journal, June 2004

Guo, H. H.; Choe, J.; Loeb, L. A.
Proceedings of the National Academy of Sciences, Vol. 101, Issue 25, p. 9205-9210
DOI: 10.1073/pnas.0403255101

Cellulase for commodity products from cellulosic biomass
journal, August 1999

Himmel, Michael E.; Ruth, Mark F.; Wyman, Charles E.
Current Opinion in Biotechnology, Vol. 10, Issue 4, p. 358-364
DOI: 10.1016/S0958-1669(99)80065-2

The use of selection in recovery of transgenic targets for mutation analysis
journal, February 1993

Lundberg, Kelly S.; Kretz, Patricia L.; Scott Provost, G.
Mutation Research Letters, Vol. 301, Issue 2, p. 99-105
DOI: 10.1016/0165-7992(93)90031-P

Microbial Cellulose Utilization: Fundamentals and Biotechnology
journal, September 2002

Lynd, L. R.; Weimer, P. J.; van Zyl, W. H.
Microbiology and Molecular Biology Reviews, Vol. 66, Issue 3, p. 506-577
DOI: 10.1128/MMBR.66.3.506-577.2002

Developments in Directed Evolution for Improving Enzyme Functions
journal, August 2007

Sen, S.; Venkata Dasu, V.; Mandal, B.
Applied Biochemistry and Biotechnology, Vol. 143, Issue 3, p. 212-223
DOI: 10.1007/s12010-007-8003-4

Prediction of protein function from protein sequence and structure
journal, January 1999

Whisstock, James C.; Lesk, Arthur M.
Quarterly Reviews of Biophysics, Vol. 36, Issue 3, p. 307-340
DOI: 10.1017/S0033583503003901

Similar Records

Similar records in DOepatents and OSTI.GOV collections:

Celluloytic enzymes, nucleic acids encoding them and methods for making and using them

Patent Gray, Kevin A ; Zhao, Lishan ; Cayouette, Michelle H

The invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, .beta.-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention.
Full Text Available November 2015
Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them

Patent Gray, Kevin A ; Zhao, Lishan ; Cayouette, Michelle H

The invention provides polypeptides having any cellulolytic activity, e.g., a cellulase activity, a endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a .beta.-xylosidase, an arabinofuranosidase, and/or an oligomerase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, .beta.-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides having an oligomerasemore »« less
Full Text Available January 2012
Cellulases, nucleic acids encoding them and methods for making and using them

Patent Blum, David ; Gemsch Cuenca, Joslin ; Dycaico, Mark

This invention relates to molecular and cellular biology and biochemistry. In one aspect, the invention provides polypeptides having cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or .beta.-glucosidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides cellulase activity, e.g., endoglucanase, cellobiohydrolase, mannanase and/or .beta.-glucosidase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts.
Full Text Available April 2013
Xylanases, nucleic acids encoding them and methods for making and using them

Patent Gray, Kevin A ; Dirmeier, Reinhard

The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal .beta.-1,4-xylosidic linkages or endo-.beta.-1,4-glucanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanasesmore »« less
Full Text Available July 2013
Xylanases, nucleic acids encoding them and methods for making and using them

Patent Gray, Kevin A. ; Dirmeier, Richard

The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal .beta.-1,4-xylosidic linkages or endo-.beta.-1,4-glucanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanasesmore »« less
Full Text Available February 2018